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Q8EE60

- DEF3_SHEON

UniProt

Q8EE60 - DEF3_SHEON

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Protein
Peptide deformylase 3
Gene
def3, SO_2530
Organism
Shewanella oneidensis (strain MR-1)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions By similarity.UniRule annotation

Catalytic activityi

Formyl-L-methionyl peptide + H2O = formate + methionyl peptide.UniRule annotation

Cofactori

Binds 1 Fe2+ ion By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi91 – 911Iron By similarity
Metal bindingi133 – 1331Iron By similarity
Active sitei134 – 1341 By similarity
Metal bindingi137 – 1371Iron By similarity

GO - Molecular functioni

  1. iron ion binding Source: InterPro
  2. peptide deformylase activity Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

  1. translation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Peptide deformylase 3 (EC:3.5.1.88)
Short name:
PDF 3
Alternative name(s):
Polypeptide deformylase 3
Gene namesi
Name:def3
Ordered Locus Names:SO_2530
OrganismiShewanella oneidensis (strain MR-1)
Taxonomic identifieri211586 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella
ProteomesiUP000008186: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 163163Peptide deformylase 3UniRule annotation
PRO_0000082836Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi211586.SO_2530.

Structurei

3D structure databases

ProteinModelPortaliQ8EE60.
SMRiQ8EE60. Positions 2-162.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0242.
HOGENOMiHOG000243509.
KOiK01462.
OMAiHPENDAD.
OrthoDBiEOG664CMF.
PhylomeDBiQ8EE60.

Family and domain databases

Gene3Di3.90.45.10. 1 hit.
HAMAPiMF_00163. Pep_deformylase.
InterProiIPR000181. Fmet_deformylase.
IPR023635. Peptide_deformylase.
[Graphical view]
PANTHERiPTHR10458. PTHR10458. 1 hit.
PfamiPF01327. Pep_deformylase. 1 hit.
[Graphical view]
PIRSFiPIRSF004749. Pep_def. 1 hit.
PRINTSiPR01576. PDEFORMYLASE.
SUPFAMiSSF56420. SSF56420. 1 hit.
TIGRFAMsiTIGR00079. pept_deformyl. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8EE60-1 [UniParc]FASTAAdd to Basket

« Hide

MAVLDILTIP DERLKRKAQP VKDIEAIQGF IDDLIETMYH TDDGIGLAST    50
QVGSTDAVIV IDLSETRDQP LVLVNPEIVE KSGEYVGEEG CLSIPGYRAK 100
VTRFEKVKVT ALDRQGKAIE IETDDFLAIV LQHEIDHLHG KVFIEHLSTL 150
KQQIALKKVR KYA 163
Length:163
Mass (Da):18,221
Last modified:March 1, 2003 - v1
Checksum:iA4A06C2952DB92EE
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE014299 Genomic DNA. Translation: AAN55560.1.
RefSeqiNP_718116.1. NC_004347.2.

Genome annotation databases

EnsemblBacteriaiAAN55560; AAN55560; SO_2530.
GeneIDi1170239.
KEGGison:SO_2530.
PATRICi23524691. VBISheOne101494_2437.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE014299 Genomic DNA. Translation: AAN55560.1 .
RefSeqi NP_718116.1. NC_004347.2.

3D structure databases

ProteinModelPortali Q8EE60.
SMRi Q8EE60. Positions 2-162.
ModBasei Search...

Protein-protein interaction databases

STRINGi 211586.SO_2530.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAN55560 ; AAN55560 ; SO_2530 .
GeneIDi 1170239.
KEGGi son:SO_2530.
PATRICi 23524691. VBISheOne101494_2437.

Phylogenomic databases

eggNOGi COG0242.
HOGENOMi HOG000243509.
KOi K01462.
OMAi HPENDAD.
OrthoDBi EOG664CMF.
PhylomeDBi Q8EE60.

Family and domain databases

Gene3Di 3.90.45.10. 1 hit.
HAMAPi MF_00163. Pep_deformylase.
InterProi IPR000181. Fmet_deformylase.
IPR023635. Peptide_deformylase.
[Graphical view ]
PANTHERi PTHR10458. PTHR10458. 1 hit.
Pfami PF01327. Pep_deformylase. 1 hit.
[Graphical view ]
PIRSFi PIRSF004749. Pep_def. 1 hit.
PRINTSi PR01576. PDEFORMYLASE.
SUPFAMi SSF56420. SSF56420. 1 hit.
TIGRFAMsi TIGR00079. pept_deformyl. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MR-1.

Entry informationi

Entry nameiDEF3_SHEON
AccessioniPrimary (citable) accession number: Q8EE60
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 27, 2003
Last sequence update: March 1, 2003
Last modified: July 9, 2014
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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