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Q8EDW2

- Q8EDW2_SHEON

UniProt

Q8EDW2 - Q8EDW2_SHEON

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Protein
Submitted name:

Isocitrate dehydrogenase NADP-dependent Icd

Gene
icd, SO_2629
Organism
Shewanella oneidensis (strain MR-1)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein predictedi

Functioni

Cofactori

Binds 1 magnesium or manganese ion per subunit By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei147 – 1471Substrate By similarity
Sitei257 – 2571Critical for catalysis By similarityUniRule annotation
Metal bindingi352 – 3521Magnesium or manganese By similarityUniRule annotation
Sitei422 – 4221Critical for catalysis By similarityUniRule annotation
Binding sitei549 – 5491Substrate By similarityUniRule annotation
Metal bindingi550 – 5501Magnesium or manganese By similarityUniRule annotation
Metal bindingi554 – 5541Magnesium or manganese By similarityUniRule annotation

GO - Molecular functioni

  1. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC
  2. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseImported

Keywords - Ligandi

MagnesiumUniRule annotation, Metal-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Isocitrate dehydrogenase NADP-dependent IcdImported (EC:1.1.1.42Imported)
Gene namesi
Name:icdImported
Ordered Locus Names:SO_2629Imported
OrganismiShewanella oneidensis (strain MR-1)Imported
Taxonomic identifieri211586 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella
ProteomesiUP000008186: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi211586.SO_2629.

Structurei

3D structure databases

ProteinModelPortaliQ8EDW2.
SMRiQ8EDW2. Positions 5-739.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni134 – 1418Substrate binding By similarity

Phylogenomic databases

HOGENOMiHOG000240860.
KOiK00031.
OMAiEEQRIGD.
OrthoDBiEOG6DVJPP.
PhylomeDBiQ8EDW2.

Family and domain databases

Gene3Di3.40.718.10. 3 hits.
InterProiIPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PfamiPF03971. IDH. 1 hit.
[Graphical view]
PIRSFiPIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsiTIGR00178. monomer_idh. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8EDW2-1 [UniParc]FASTAAdd to Basket

« Hide

MKDNSPTIIY TETDEAPALA TLSLLPIIKT FTNAADVAVE TRDISLSGRV    50
IANFPEKLTD AQKIGDHLAE LGDLANQPEA NIIKLPNISA SIPQLKACIL 100
ELQQKGYDIP NYPDEPKTDE EKSIKARYDK IKGSAVNPVL REGNSDRRAP 150
LSVKNFAKKN PHSMGKWVKD SKSHVAHMSE GDFYGSELSV TLSNADTVNI 200
VLAQKDGQEV VLKSGLKLLA GEIIDASVMS KKALVSFFER EIANAKAENV 250
LLSLHLKATM MKVSDPIMFG HAVKVFFKPV FDKHAALFAE LGVDVNNGFG 300
DVYAKIASLP TDVRSQIEAD IAAVYAEGPA LAMVDSDKGI TNLHVPSDII 350
IDASMPAAIR SSGQMWGPDG KLHDTKALIP DRCYAGVYQE TIAFCKEHGA 400
FDPSTMGSVP NVGLMAQKAE EYGSHDKTFE IPADGVVNVI DASGKVLMSH 450
NVEAGDIWRM CQVKDAPIRD WVKLAVRRAR LSNTPAVFWL DANRAHDAQL 500
IVKVKQYLPE HDTSGLDISI MSPEEATRFS LARIKEGKDT ISVTGNVLRD 550
YLTDLFPILE LGTSAKMLSI VPLMNGGGLF ETGAGGSAPK HVQQVEKEGH 600
LRWDSLGEFL ALAASLEHLS QTVGNPKAQV LADTLDQAIG QFLDSNKSPS 650
RRVGELDNRG SHFYLAMYWA QALAVQTKDE QLQAHFIPLA HALSANEQVI 700
VAELNNAQGA PVDLGGYYRL DAVKAEKAMR PSETLNKLLI A 741
Length:741
Mass (Da):80,501
Last modified:March 1, 2003 - v1
Checksum:iA9F17C40A617ECE7
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE014299 Genomic DNA. Translation: AAN55658.1.
RefSeqiNP_718214.1. NC_004347.2.

Genome annotation databases

EnsemblBacteriaiAAN55658; AAN55658; SO_2629.
GeneIDi1170331.
KEGGison:SO_2629.
PATRICi23524885. VBISheOne101494_2532.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE014299 Genomic DNA. Translation: AAN55658.1 .
RefSeqi NP_718214.1. NC_004347.2.

3D structure databases

ProteinModelPortali Q8EDW2.
SMRi Q8EDW2. Positions 5-739.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 211586.SO_2629.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAN55658 ; AAN55658 ; SO_2629 .
GeneIDi 1170331.
KEGGi son:SO_2629.
PATRICi 23524885. VBISheOne101494_2532.

Phylogenomic databases

HOGENOMi HOG000240860.
KOi K00031.
OMAi EEQRIGD.
OrthoDBi EOG6DVJPP.
PhylomeDBi Q8EDW2.

Family and domain databases

Gene3Di 3.40.718.10. 3 hits.
InterProi IPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view ]
Pfami PF03971. IDH. 1 hit.
[Graphical view ]
PIRSFi PIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsi TIGR00178. monomer_idh. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MR-1Imported.

Entry informationi

Entry nameiQ8EDW2_SHEON
AccessioniPrimary (citable) accession number: Q8EDW2
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: July 9, 2014
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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