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Q8EDW2 (Q8EDW2_SHEON) Unreviewed, UniProtKB/TrEMBL

Last modified December 11, 2013. Version 73. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein names
EC=1.1.1.42 EMBL AAN55658.1
Gene names
Name:icd EMBL AAN55658.1
Ordered Locus Names:SO_2629 EMBL AAN55658.1
OrganismShewanella oneidensis (strain MR-1) [Reference proteome] [HAMAP] EMBL AAN55658.1
Taxonomic identifier211586 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella

Protein attributes

Sequence length741 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Cofactor

Binds 1 magnesium or manganese ion per subunit By similarity. PIRSR PIRSR009407-3

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Region134 – 1418Substrate binding By similarity PIRSR PIRSR009407-2

Sites

Metal binding3521Magnesium or manganese By similarity PIRSR PIRSR009407-3
Metal binding5501Magnesium or manganese By similarity PIRSR PIRSR009407-3
Metal binding5541Magnesium or manganese By similarity PIRSR PIRSR009407-3
Binding site1471Substrate By similarity PIRSR PIRSR009407-2
Binding site5491Substrate By similarity PIRSR PIRSR009407-2
Site2571Critical for catalysis By similarity
Site4221Critical for catalysis By similarity

Sequences

Sequence LengthMass (Da)Tools
Q8EDW2 [UniParc].

Last modified March 1, 2003. Version 1.
Checksum: A9F17C40A617ECE7

FASTA74180,501
        10         20         30         40         50         60 
MKDNSPTIIY TETDEAPALA TLSLLPIIKT FTNAADVAVE TRDISLSGRV IANFPEKLTD 

        70         80         90        100        110        120 
AQKIGDHLAE LGDLANQPEA NIIKLPNISA SIPQLKACIL ELQQKGYDIP NYPDEPKTDE 

       130        140        150        160        170        180 
EKSIKARYDK IKGSAVNPVL REGNSDRRAP LSVKNFAKKN PHSMGKWVKD SKSHVAHMSE 

       190        200        210        220        230        240 
GDFYGSELSV TLSNADTVNI VLAQKDGQEV VLKSGLKLLA GEIIDASVMS KKALVSFFER 

       250        260        270        280        290        300 
EIANAKAENV LLSLHLKATM MKVSDPIMFG HAVKVFFKPV FDKHAALFAE LGVDVNNGFG 

       310        320        330        340        350        360 
DVYAKIASLP TDVRSQIEAD IAAVYAEGPA LAMVDSDKGI TNLHVPSDII IDASMPAAIR 

       370        380        390        400        410        420 
SSGQMWGPDG KLHDTKALIP DRCYAGVYQE TIAFCKEHGA FDPSTMGSVP NVGLMAQKAE 

       430        440        450        460        470        480 
EYGSHDKTFE IPADGVVNVI DASGKVLMSH NVEAGDIWRM CQVKDAPIRD WVKLAVRRAR 

       490        500        510        520        530        540 
LSNTPAVFWL DANRAHDAQL IVKVKQYLPE HDTSGLDISI MSPEEATRFS LARIKEGKDT 

       550        560        570        580        590        600 
ISVTGNVLRD YLTDLFPILE LGTSAKMLSI VPLMNGGGLF ETGAGGSAPK HVQQVEKEGH 

       610        620        630        640        650        660 
LRWDSLGEFL ALAASLEHLS QTVGNPKAQV LADTLDQAIG QFLDSNKSPS RRVGELDNRG 

       670        680        690        700        710        720 
SHFYLAMYWA QALAVQTKDE QLQAHFIPLA HALSANEQVI VAELNNAQGA PVDLGGYYRL 

       730        740 
DAVKAEKAMR PSETLNKLLI A 

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE014299 Genomic DNA. Translation: AAN55658.1.
RefSeqNP_718214.1. NC_004347.2.

3D structure databases

ProteinModelPortalQ8EDW2.
SMRQ8EDW2. Positions 5-739.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING211586.SO_2629.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAN55658; AAN55658; SO_2629.
GeneID1170331.
KEGGson:SO_2629.
PATRIC23524885. VBISheOne101494_2532.

Phylogenomic databases

HOGENOMHOG000240860.
KOK00031.
OMAGYLRWDS.
OrthoDBEOG6DVJPP.
ProtClustDBCLSK867411.

Family and domain databases

Gene3D3.40.718.10. 3 hits.
InterProIPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PfamPF03971. IDH. 1 hit.
[Graphical view]
PIRSFPIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsTIGR00178. monomer_idh. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ8EDW2_SHEON
AccessionPrimary (citable) accession number: Q8EDW2
Entry history
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: December 11, 2013
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)