Q8EDK9 (Q8EDK9_SHEON) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Dethiobiotin synthase EMBL AAN55765.1

Gene names

Name:	bioD EMBL AAN55765.1
Ordered Locus Names:	SO_2737

Organism

Shewanella oneidensis

Taxonomic identifier

70863 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Shewanellaceae › Shewanella

Protein attributes

Sequence length	231 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring By similarity. SAAS SAAS004472
Catalytic activity	ATP + 7,8-diaminononanoate + CO2 = ADP + phosphate + dethiobiotin. SAAS SAAS004472
Cofactor	Magnesium By similarity. SAAS SAAS004472
Pathway	Cofactor biosynthesis; biotin biosynthesis; biotin from 7,8-diaminononanoate: step 1/2. SAAS SAAS004472
Subcellular location	Cytoplasm By similarity SAAS SAAS004472.

Ontologies

Keywords
Biological process	Biotin biosynthesis SAAS SAAS004472
Cellular component	Cytoplasm SAAS SAAS004472
Ligand	ATP-binding SAAS SAAS004472 Magnesium SAAS SAAS004472 Metal-binding SAAS SAAS004472 Nucleotide-binding
Molecular function	Ligase SAAS SAAS004472
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	biotin biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW dethiobiotin synthase activity Inferred from electronic annotation. Source: InterPro magnesium ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8EDK9 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: 8FB7C34CDEF88A8F	FASTA	231	24,875
	10 20 30 40 50 60 MFFVTGTDTD SGKTLVSTAL LTAFNRDVLR AGSSRLSLGV KPVASGCEIT EKGLRNSDAL 70 80 90 100 110 120 KLMSASSLKL SYEQVNPISF EPAIAPHIAA KQQRVNLSPE AILAKLDRQA WAQADFCLIE 130 140 150 160 170 180 GAGGWRLPLG EGRYLSELVQ QLNLPVILVV GMKLGCLNHA LLTQEAILAD GLTVAGWVAN 190 200 210 220 230 CVDPNMSVFD ENLASLKEMM VSPFLGCIPH LKQADAEHAA NFMNIQPLLM K

References

[1]

"Genome sequence of the dissimilatory metal ion-reducing bacterium Shewanella oneidensis." Heidelberg J.F., Paulsen I.T., Nelson K.E., Gaidos E.J., Nelson W.C., Read T.D., Eisen J.A., Seshadri R., Ward N.L., Methe B.A., Clayton R.A., Meyer T., Tsapin A., Scott J., Beanan M.J., Brinkac L.M., Daugherty S.C., DeBoy R.T. , Dodson R.J., Durkin A.S., Haft D.H., Kolonay J.F., Madupu R., Peterson J.D., Umayam L.A., White O., Wolf A.M., Vamathevan J.J., Weidman J.F., Impraim M., Lee K., Berry K.J., Lee C., Mueller J., Khouri H.M., Gill J., Utterback T.R., McDonald L.A., Feldblyum T.V., Smith H.O., Venter J.C., Nealson K.H., Fraser C.M. Nat. Biotechnol. 20:1118-1123(2002) [PubMed: 12368813] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: MR-1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE014299 Genomic DNA. Translation: AAN55765.1.
RefSeq	NP_718321.1. NC_004347.1.
3D structure databases
HSSP	HSSP built from PDB template 1DTS based on UniProtKB P13000.
ProteinModelPortal	Q8EDK9.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1170435.
GenomeReviews	Gene locus SO_2737 in contig AE014299_GR.
KEGG	son:SO_2737.
NMPDR	fig|211586.1.peg.2487.
PATRIC	23525093. VBISheOne101494_2636.
TIGR	SO_2737.
Phylogenomic databases
HOGENOM	HBG650065.
OMA	ANCVDPN.
ProtClustDB	PRK00090.
Enzyme and pathway databases
BioCyc	SONE211586:SO_2737-MONOMER.
Family and domain databases
HAMAP	MF_00336. BioD. [Tree]
InterPro	IPR002586. CbiA_P_synth. IPR004472. DTB_synth_BioD. [Graphical view]
KO	K01935.
Pfam	PF01656. CbiA. 1 hit. [Graphical view]
PIRSF	PIRSF006755. DTB_synth. 1 hit.
TIGRFAMs	TIGR00347. BioD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q8EDK9_SHEON

Accession

Primary (citable) accession number: Q8EDK9

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2003
Last sequence update:	March 1, 2003
Last modified:	December 14, 2011
This is version 63 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)