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Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Shewanella oneidensis (strain MR-1)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathway:iglycolysis

This protein is involved in step 2 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose.UniRule annotation
Proteins known to be involved in the 4 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Glucose-6-phosphate isomerase (pgi)
  3. no protein annotated in this organism
  4. no protein annotated in this organism
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose, the pathway glycolysis and in Carbohydrate degradation.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei351 – 3511Proton donorUniRule annotation
Active sitei382 – 3821UniRule annotation
Active sitei510 – 5101UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

UniPathwayiUPA00109; UER00181.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgiUniRule annotation
Ordered Locus Names:SO_3547
OrganismiShewanella oneidensis (strain MR-1)
Taxonomic identifieri211586 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella
ProteomesiUP000008186 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 545545Glucose-6-phosphate isomerasePRO_0000180724Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi211586.SO_3547.

Structurei

3D structure databases

ProteinModelPortaliQ8EBH1.
SMRiQ8EBH1. Positions 3-544.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000261370.
KOiK01810.
OMAiSHLIAPY.
OrthoDBiEOG64R61J.
PhylomeDBiQ8EBH1.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8EBH1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTILTQSTTW QALSAHSQDI PHMRELFAAD PARFTKMSLS SCGLFLDYSK
60 70 80 90 100
NRATPETLNL LFALAQEAKL DAKIKAMFAG DIINTTEKRA VLHTALRNTA
110 120 130 140 150
EQCIIAEGQD IVPEVQQTLN KMQQFVTSVT SGQWKGYTGK AITDIVSIGI
160 170 180 190 200
GGSFLGPKIV SQALRPYWIT GLNCHFVANV DGTSISEKLK LLDPETTLFI
210 220 230 240 250
MSSKSFGTQE TLTNTLTAKA WFLAKGGSQS DVAKHFAAVT SNVVKATGFG
260 270 280 290 300
IDANNIFPMW DWVGGRYSLW SAIGLPIALL IGMDNFRALL KGAHQMDTHF
310 320 330 340 350
ANAPLTENMP VIMGLLSLWY GNFFNAQSHV VLTYDHYLRG LPAYFQQLDM
360 370 380 390 400
ESNGKSVTLN GTHVDYSTGP VIWGGEGTNG QHAYHQLLHQ GTALIPADFI
410 420 430 440 450
MPLQSHNPIG EHHDQLASNC FGQTQALMQG RTLDEALAEL SKSALSNEEK
460 470 480 490 500
LLIAKHKVMS GNKPSNTLLM DKLTPETLGA LIALYEHRTF VQGAIWDINS
510 520 530 540
FDQWGVELGK TLGNDVLTRI GADQEATVLD ASSNGLINLY RRGKI
Length:545
Mass (Da):59,662
Last modified:March 1, 2003 - v1
Checksum:i8135086AFB8F8DE9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014299 Genomic DNA. Translation: AAN56538.1.
RefSeqiNP_719094.1. NC_004347.2.
WP_011073376.1. NC_004347.2.

Genome annotation databases

EnsemblBacteriaiAAN56538; AAN56538; SO_3547.
GeneIDi1171218.
KEGGison:SO_3547.
PATRICi23526780. VBISheOne101494_3441.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014299 Genomic DNA. Translation: AAN56538.1.
RefSeqiNP_719094.1. NC_004347.2.
WP_011073376.1. NC_004347.2.

3D structure databases

ProteinModelPortaliQ8EBH1.
SMRiQ8EBH1. Positions 3-544.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi211586.SO_3547.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAN56538; AAN56538; SO_3547.
GeneIDi1171218.
KEGGison:SO_3547.
PATRICi23526780. VBISheOne101494_3441.

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000261370.
KOiK01810.
OMAiSHLIAPY.
OrthoDBiEOG64R61J.
PhylomeDBiQ8EBH1.

Enzyme and pathway databases

UniPathwayiUPA00109; UER00181.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MR-1.

Entry informationi

Entry nameiG6PI_SHEON
AccessioniPrimary (citable) accession number: Q8EBH1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 23, 2003
Last sequence update: March 1, 2003
Last modified: July 22, 2015
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.