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Q8EBH1 (G6PI_SHEON) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 70. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucose-6-phosphate isomerase

Short name=GPI
EC=5.3.1.9
Alternative name(s):
Phosphoglucose isomerase
Short name=PGI
Phosphohexose isomerase
Short name=PHI
Gene names
Name:pgi
Ordered Locus Names:SO_3547
OrganismShewanella oneidensis (strain MR-1) [Reference proteome] [HAMAP]
Taxonomic identifier211586 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella

Protein attributes

Sequence length545 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP-Rule MF_00473

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP-Rule MF_00473

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00473.

Sequence similarities

Belongs to the GPI family.

Ontologies

Keywords
   Biological processGluconeogenesis
Glycolysis
   Cellular componentCytoplasm
   Molecular functionIsomerase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processgluconeogenesis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glycolytic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionglucose-6-phosphate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 545545Glucose-6-phosphate isomerase HAMAP-Rule MF_00473
PRO_0000180724

Sites

Active site3511Proton donor By similarity
Active site3821 By similarity
Active site5101 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q8EBH1 [UniParc].

Last modified March 1, 2003. Version 1.
Checksum: 8135086AFB8F8DE9

FASTA54559,662
        10         20         30         40         50         60 
MTILTQSTTW QALSAHSQDI PHMRELFAAD PARFTKMSLS SCGLFLDYSK NRATPETLNL 

        70         80         90        100        110        120 
LFALAQEAKL DAKIKAMFAG DIINTTEKRA VLHTALRNTA EQCIIAEGQD IVPEVQQTLN 

       130        140        150        160        170        180 
KMQQFVTSVT SGQWKGYTGK AITDIVSIGI GGSFLGPKIV SQALRPYWIT GLNCHFVANV 

       190        200        210        220        230        240 
DGTSISEKLK LLDPETTLFI MSSKSFGTQE TLTNTLTAKA WFLAKGGSQS DVAKHFAAVT 

       250        260        270        280        290        300 
SNVVKATGFG IDANNIFPMW DWVGGRYSLW SAIGLPIALL IGMDNFRALL KGAHQMDTHF 

       310        320        330        340        350        360 
ANAPLTENMP VIMGLLSLWY GNFFNAQSHV VLTYDHYLRG LPAYFQQLDM ESNGKSVTLN 

       370        380        390        400        410        420 
GTHVDYSTGP VIWGGEGTNG QHAYHQLLHQ GTALIPADFI MPLQSHNPIG EHHDQLASNC 

       430        440        450        460        470        480 
FGQTQALMQG RTLDEALAEL SKSALSNEEK LLIAKHKVMS GNKPSNTLLM DKLTPETLGA 

       490        500        510        520        530        540 
LIALYEHRTF VQGAIWDINS FDQWGVELGK TLGNDVLTRI GADQEATVLD ASSNGLINLY 


RRGKI 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE014299 Genomic DNA. Translation: AAN56538.1.
RefSeqNP_719094.1. NC_004347.2.

3D structure databases

ProteinModelPortalQ8EBH1.
SMRQ8EBH1. Positions 3-544.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING211586.SO_3547.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAN56538; AAN56538; SO_3547.
GeneID1171218.
KEGGson:SO_3547.
PATRIC23526780. VBISheOne101494_3441.

Phylogenomic databases

eggNOGCOG0166.
HOGENOMHOG000261370.
KOK01810.
OMANCHFVAN.
OrthoDBEOG64R61J.
PhylomeDBQ8EBH1.

Enzyme and pathway databases

UniPathwayUPA00109; UER00181.

Family and domain databases

Gene3D1.10.1390.10. 1 hit.
HAMAPMF_00473. G6P_isomerase.
InterProIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERPTHR11469. PTHR11469. 1 hit.
PfamPF00342. PGI. 1 hit.
[Graphical view]
PRINTSPR00662. G6PISOMERASE.
PROSITEPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG6PI_SHEON
AccessionPrimary (citable) accession number: Q8EBH1
Entry history
Integrated into UniProtKB/Swiss-Prot: May 23, 2003
Last sequence update: March 1, 2003
Last modified: July 9, 2014
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways