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Q8EB78

- UNG_SHEON

UniProt

Q8EB78 - UNG_SHEON

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Protein

Uracil-DNA glycosylase

Gene
ung, SO_3654
Organism
Shewanella oneidensis (strain MR-1)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine By similarity.UniRule annotation

Catalytic activityi

Hydrolyzes single-stranded DNA or mismatched double-stranded DNA and polynucleotides, releasing free uracil.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei60 – 601Proton acceptor By similarity

GO - Molecular functioni

  1. uracil DNA N-glycosylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. base-excision repair Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Glycosidase, Hydrolase

Keywords - Biological processi

DNA damage, DNA repair

Names & Taxonomyi

Protein namesi
Recommended name:
Uracil-DNA glycosylase (EC:3.2.2.27)
Short name:
UDG
Gene namesi
Name:ung
Ordered Locus Names:SO_3654
OrganismiShewanella oneidensis (strain MR-1)
Taxonomic identifieri211586 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella
ProteomesiUP000008186: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 218218Uracil-DNA glycosylaseUniRule annotationPRO_0000176135Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi211586.SO_3654.

Structurei

3D structure databases

ProteinModelPortaliQ8EB78.
SMRiQ8EB78. Positions 1-217.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0692.
HOGENOMiHOG000229528.
KOiK03648.
OMAiQNIFKEM.
OrthoDBiEOG6MSS63.
PhylomeDBiQ8EB78.

Family and domain databases

Gene3Di3.40.470.10. 1 hit.
HAMAPiMF_00148. UDG.
InterProiIPR018085. Ura-DNA_Glyclase_AS.
IPR002043. Ura_DNA_glycsylse.
IPR005122. Uracil-DNA_glycosylase-like.
[Graphical view]
PANTHERiPTHR11264. PTHR11264. 1 hit.
PfamiPF03167. UDG. 1 hit.
[Graphical view]
SMARTiSM00986. UDG. 1 hit.
[Graphical view]
SUPFAMiSSF52141. SSF52141. 1 hit.
TIGRFAMsiTIGR00628. ung. 1 hit.
PROSITEiPS00130. U_DNA_GLYCOSYLASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8EB78-1 [UniParc]FASTAAdd to Basket

« Hide

MTWPAFIDHQ RTQPYYQQLI AFVNQERQVG KVIYPPKEDV FNAFKTTPLE    50
QVRVVLIGQD PYHGPDQAHG LCFSVKRGVK APPSLANMYK ELVNDIPGFH 100
IPNHGDLTQW AEQGILMLNT VLTVEQGQAH SHANAGWEIF TTEALKLLNA 150
QERPIIFVLW GSHAIKKGAV ITAPQHQILS GPHPSPLSAY RGFFGCGHFS 200
KVNQLLMARG EAPIQWQI 218
Length:218
Mass (Da):24,434
Last modified:March 1, 2003 - v1
Checksum:i751FF4DC183851B3
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE014299 Genomic DNA. Translation: AAN56640.1.
RefSeqiNP_719196.1. NC_004347.2.

Genome annotation databases

EnsemblBacteriaiAAN56640; AAN56640; SO_3654.
GeneIDi1171313.
KEGGison:SO_3654.
PATRICi23526994. VBISheOne101494_3542.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE014299 Genomic DNA. Translation: AAN56640.1 .
RefSeqi NP_719196.1. NC_004347.2.

3D structure databases

ProteinModelPortali Q8EB78.
SMRi Q8EB78. Positions 1-217.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 211586.SO_3654.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAN56640 ; AAN56640 ; SO_3654 .
GeneIDi 1171313.
KEGGi son:SO_3654.
PATRICi 23526994. VBISheOne101494_3542.

Phylogenomic databases

eggNOGi COG0692.
HOGENOMi HOG000229528.
KOi K03648.
OMAi QNIFKEM.
OrthoDBi EOG6MSS63.
PhylomeDBi Q8EB78.

Family and domain databases

Gene3Di 3.40.470.10. 1 hit.
HAMAPi MF_00148. UDG.
InterProi IPR018085. Ura-DNA_Glyclase_AS.
IPR002043. Ura_DNA_glycsylse.
IPR005122. Uracil-DNA_glycosylase-like.
[Graphical view ]
PANTHERi PTHR11264. PTHR11264. 1 hit.
Pfami PF03167. UDG. 1 hit.
[Graphical view ]
SMARTi SM00986. UDG. 1 hit.
[Graphical view ]
SUPFAMi SSF52141. SSF52141. 1 hit.
TIGRFAMsi TIGR00628. ung. 1 hit.
PROSITEi PS00130. U_DNA_GLYCOSYLASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MR-1.

Entry informationi

Entry nameiUNG_SHEON
AccessioniPrimary (citable) accession number: Q8EB78
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 20, 2003
Last sequence update: March 1, 2003
Last modified: July 9, 2014
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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