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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Shewanella oneidensis (strain MR-1)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciSONE211586:G1GMP-3809-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:SO_4123
OrganismiShewanella oneidensis (strain MR-1)
Taxonomic identifieri211586 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella
Proteomesi
  • UP000008186 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001516031 – 581Arginine--tRNA ligaseAdd BLAST581

Proteomic databases

PaxDbiQ8E9Y7

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi211586.SO_4123

Structurei

3D structure databases

ProteinModelPortaliQ8E9Y7
SMRiQ8E9Y7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi126 – 136"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C75 Bacteria
COG0018 LUCA
HOGENOMiHOG000247212
KOiK01887
OMAiNKPLHLG
OrthoDBiPOG091H01RF
PhylomeDBiQ8E9Y7

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.30.1360.70, 1 hit
3.40.50.620, 1 hit
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 1 hit
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit

Sequencei

Sequence statusi: Complete.

Q8E9Y7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKSHIQSLLE QTIESFKQQG ILPADFEARI QVDRTKDKSH GDLATNVAMM
60 70 80 90 100
LTKAAGKNPR ELAQLIIDNL PASAYVAKVE IAGPGFINFF IDDSALANQL
110 120 130 140 150
QAAIGDEHLG IKLPAPQTVV VDYSSPNLAK EMHVGHLRST IIGDSVVRTL
160 170 180 190 200
EFLGHKVIRQ NHVGDWGTQF GMLLAYMEEL RAANGEQAQL ELSDLETFYR
210 220 230 240 250
AAKLRFDESA EFATRARQLV VALQSGDEYC NKLWREFNDI SLSHCHEVYE
260 270 280 290 300
RLGVSLTRAD VHGESAYNAD LEQVVNDLAA KGLLTESNGA KVVFQEEFRT
310 320 330 340 350
KEGEPLPVII QKADGGYLYA TTDLAAMRYR SNVLKADRVL YFVDLRQALH
360 370 380 390 400
FQQVFSLAKL AKFVREDMSL EHLGFGTMNG EDGRPFKTRT GGVVKLVDLL
410 420 430 440 450
DEANTRALEL VRSKNPDMDE ATLAEIARVV GISAVKYADL SKNRTSDYIF
460 470 480 490 500
SFEQMLSFEG NTAPYLLYAY TRVAGIFKRA TDVDLSQAKI VLEHEKEKDL
510 520 530 540 550
GNKLAQFGEI LSRVVDKGQP HVLCGYLYEL AGAFSSFYEA CPVLAADNDE
560 570 580
QKHSRLLLSQ LTASTLQKGL NLLGIETLER M
Length:581
Mass (Da):64,638
Last modified:March 1, 2003 - v1
Checksum:i068665A3ABE42902
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014299 Genomic DNA Translation: AAN57096.1
RefSeqiNP_719652.1, NC_004347.2
WP_011073824.1, NC_004347.2

Genome annotation databases

EnsemblBacteriaiAAN57096; AAN57096; SO_4123
GeneIDi1171736
KEGGison:SO_4123
PATRICifig|211586.12.peg.3988

Similar proteinsi

Entry informationi

Entry nameiSYR_SHEON
AccessioniPrimary (citable) accession number: Q8E9Y7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 14, 2003
Last sequence update: March 1, 2003
Last modified: April 25, 2018
This is version 97 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health