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Q8E9Y7 (SYR_SHEON) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 73. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:SO_4123
OrganismShewanella oneidensis (strain MR-1) [Reference proteome] [HAMAP]
Taxonomic identifier211586 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella

Protein attributes

Sequence length581 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 581581Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_0000151603

Regions

Motif126 – 13611"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
Q8E9Y7 [UniParc].

Last modified March 1, 2003. Version 1.
Checksum: 068665A3ABE42902

FASTA58164,638
        10         20         30         40         50         60 
MKSHIQSLLE QTIESFKQQG ILPADFEARI QVDRTKDKSH GDLATNVAMM LTKAAGKNPR 

        70         80         90        100        110        120 
ELAQLIIDNL PASAYVAKVE IAGPGFINFF IDDSALANQL QAAIGDEHLG IKLPAPQTVV 

       130        140        150        160        170        180 
VDYSSPNLAK EMHVGHLRST IIGDSVVRTL EFLGHKVIRQ NHVGDWGTQF GMLLAYMEEL 

       190        200        210        220        230        240 
RAANGEQAQL ELSDLETFYR AAKLRFDESA EFATRARQLV VALQSGDEYC NKLWREFNDI 

       250        260        270        280        290        300 
SLSHCHEVYE RLGVSLTRAD VHGESAYNAD LEQVVNDLAA KGLLTESNGA KVVFQEEFRT 

       310        320        330        340        350        360 
KEGEPLPVII QKADGGYLYA TTDLAAMRYR SNVLKADRVL YFVDLRQALH FQQVFSLAKL 

       370        380        390        400        410        420 
AKFVREDMSL EHLGFGTMNG EDGRPFKTRT GGVVKLVDLL DEANTRALEL VRSKNPDMDE 

       430        440        450        460        470        480 
ATLAEIARVV GISAVKYADL SKNRTSDYIF SFEQMLSFEG NTAPYLLYAY TRVAGIFKRA 

       490        500        510        520        530        540 
TDVDLSQAKI VLEHEKEKDL GNKLAQFGEI LSRVVDKGQP HVLCGYLYEL AGAFSSFYEA 

       550        560        570        580 
CPVLAADNDE QKHSRLLLSQ LTASTLQKGL NLLGIETLER M 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE014299 Genomic DNA. Translation: AAN57096.1.
RefSeqNP_719652.1. NC_004347.2.

3D structure databases

ProteinModelPortalQ8E9Y7.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING211586.SO_4123.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAN57096; AAN57096; SO_4123.
GeneID1171736.
KEGGson:SO_4123.
PATRIC23527888. VBISheOne101494_3988.

Phylogenomic databases

eggNOGCOG0018.
HOGENOMHOG000247212.
KOK01887.
OMANPNGPLH.
OrthoDBEOG6JB13C.
ProtClustDBPRK01611.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYR_SHEON
AccessionPrimary (citable) accession number: Q8E9Y7
Entry history
Integrated into UniProtKB/Swiss-Prot: November 14, 2003
Last sequence update: March 1, 2003
Last modified: April 16, 2014
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries