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Q8E8Q9 (PLSB_SHEON) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 58. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Glycerol-3-phosphate acyltransferase
Short name=GPAT
EC=2.3.1.15
Gene names
Name:plsB
Ordered Locus Names:SO_4602
OrganismShewanella oneidensis
Taxonomic identifier70863 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Shewanellaceae › Shewanella

Protein attributes

Sequence length809 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Acyl-CoA + sn-glycerol 3-phosphate = CoA + 1-acyl-sn-glycerol 3-phosphate. HAMAP MF_00393

Pathway

Phospholipid metabolism; CDP-diacylglycerol biosynthesis; CDP-diacylglycerol from sn-glycerol 3-phosphate: step 1/3. HAMAP MF_00393

Subcellular location

Cell inner membrane; Peripheral membrane protein; Cytoplasmic side By similarity HAMAP MF_00393.

Domain

The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate By similarity. HAMAP MF_00393

Sequence similarities

Belongs to the GPAT/DAPAT family.

Ontologies

Keywords
   Biological processPhospholipid biosynthesis
   Cellular componentCell inner membrane
Cell membrane
Membrane
   Molecular functionAcyltransferase
Transferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological processphospholipid biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentplasma membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionglycerol-3-phosphate O-acyltransferase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 809809Glycerol-3-phosphate acyltransferase HAMAP MF_00393
PRO_0000195233

Regions

Motif309 – 3146HXXXXD motif HAMAP MF_00393

Sequences

Sequence LengthMass (Da)Tools
Q8E8Q9 [UniParc].

Last modified March 1, 2003. Version 1.
Checksum: 9E5DD163FAB93DD3

FASTA80991,562
        10         20         30         40         50         60 
MPKQDSLWLK SLRWIQKYLV HTIVVPQDPF ADLNLDASRP LAYVMKTESL SDIAALSEIT 

        70         80         90        100        110        120 
AKLGLPSPYE PLVVNGVVAP RVVCLEGRKP LFGDRASNEP FLECFMRLLA VHKEKPELDI 

       130        140        150        160        170        180 
QLVPVSLYWG RTPGKEDDTM KAAVLERENP TWLRKCLMIL FLGRHNFVQF SNAVSLRYMA 

       190        200        210        220        230        240 
DEHGTDMGIA HKLARVARVH FRRQRKVMTG PVLPNRQALF DSLLKSESLR KAIQEEAASK 

       250        260        270        280        290        300 
KISETQARET AIEYLDEIAA NYSDSLVRIA ERFLTWLWNK LYSGINIKGA EQIRQLHHDG 

       310        320        330        340        350        360 
HEIVYVPCHR SHMDYLLLSY ILYYQGMVPP HIAAGINLNF WPAGPLFRRG GAFFIRRSFN 

       370        380        390        400        410        420 
GNKLYTAVFR EYLDQLFAKG YSVEYFSEGG RSRTGRLLAP KTGMIAMTIN SVLRGIERPV 

       430        440        450        460        470        480 
TLVPVYLGYD HVMEVATYHK ELSGKKKQKE SVWQVFGAIR KLGNFGQGYV NFGEPITLQN 

       490        500        510        520        530        540 
FLNETAPNWR SEVADDPEQK PTWLTPAVNV LANRVMTRIN DAAAASSITL TSLVLLASEQ 

       550        560        570        580        590        600 
NALERCLLER QLDLYLTLLK RVPYTSFTSV AEGDGKHLVQ QGLELNKFSI SADPLGEIVS 

       610        620        630        640        650        660 
IDDKQAISMT YYRNNIIHLF IIPSLIASCL INNKQISRAQ IFGVVNDFYP LLKAELFMGI 

       670        680        690        700        710        720 
KDLPSYVDQV LDLFIEQGLV EETELLSVAT ERASQMLLLA GSVNETLQRY AIIFNLLAHR 

       730        740        750        760        770        780 
PKMERSDLES ESHLLAQRLG ALHGITAPEF YDKKLYNTLS VKLKELGYFS GKEDKSDVER 

       790        800 
IREQANNLLR ASVRQTIVAS VTAEQSFNG

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE014299 Genomic DNA. Translation: AAN57562.1.
RefSeqNP_720118.1. NC_004347.1.

3D structure databases

ProteinModelPortalQ8E8Q9.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1172186.
GenomeReviewsGene locus SO_4602 in contig AE014299_GR.
KEGGson:SO_4602.
NMPDRfig|211586.1.peg.4176.
PATRIC23528869. VBISheOne101494_4460.
TIGRSO_4602.

Phylogenomic databases

HOGENOMHBG296590.
OMAWNKLYQG.
ProtClustDBPRK04974.

Enzyme and pathway databases

BioCycSONE211586:SO_4602-MONOMER.

Family and domain databases

HAMAPMF_00393. Glyc3P_acyltrans.
[Tree]
InterProIPR002123. Acyltransferase.
IPR022284. G3P_O-AcylTrfase.
[Graphical view]
KOK00631.
PfamPF01553. Acyltransferase. 1 hit.
[Graphical view]
PIRSFPIRSF000437. GPAT_DHAPAT. 1 hit.
SMARTSM00563. PlsC. 1 hit.
[Graphical view]
TIGRFAMsTIGR03703. PlsB. 1 hit.
ProtoNetSearch...

Entry information

Entry namePLSB_SHEON
AccessionPrimary (citable) accession number: Q8E8Q9
Entry history
Integrated into UniProtKB/Swiss-Prot: May 24, 2004
Last sequence update: March 1, 2003
Last modified: January 25, 2012
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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