Q8E6I5 (WHIA_STRA3) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative sporulation transcription regulator WhiA

Gene names

Name:	whiA
Ordered Locus Names:	gbs0578

Organism

Streptococcus agalactiae serotype III (strain NEM316) [Complete proteome] [HAMAP]

Taxonomic identifier

211110 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Bacilli › Lactobacillales › Streptococcaceae › Streptococcus › Streptococcus agalactiae › Streptococcus agalactiae serogroup III

Protein attributes

Sequence length	303 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	May be required for sporulation By similarity.
Sequence similarities	Belongs to the WhiA transcriptional regulatory family.

Ontologies

Keywords
Biological process	Transcription Transcription regulation
Ligand	DNA-binding
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	regulation of sporulation Inferred from electronic annotation. Source: HAMAP regulation of transcription, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW transcription, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	DNA binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 303	303	Putative sporulation transcription regulator WhiA HAMAP-Rule MF_01420		PRO_0000376571
Regions
	DNA binding	272 – 303	32	H-T-H motif Potential

Sequences

	Sequence		Length	Mass (Da)
	Q8E6I5 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: DB494200EBB4FD39	FASTA	303	34,381
	10 20 30 40 50 60 MSFTVKVKEE LLGHKSENKM ELSAIIKMSG SLGLANHGLN LSITTENAKI ARHIYSMLEE 70 80 90 100 110 120 HYHLQPEIKY HQKTNLRKNR VYTVFIEEKV DVILADLKLA DAFFGIETGI EHSILDNDEN 130 140 150 160 170 180 GRAYLRGAFL STGTVREPDS GKYQLEIFSV YLDHAQDLAN LMKKFMLDAK VIEHKHGAVT 190 200 210 220 230 240 YLQKAEDIMD FLIVIDAMEA RDAFEEIKMI RETRNDINRA NNVETANIAR TITASMKTIN 250 260 270 280 290 300 NIIKIMDTIG FDALPSDLRQ VAQVRVAHPD YSIQQIADSL ETPLSKSGVN HRLRKINKIA DEL

References

[1]

"Genome sequence of Streptococcus agalactiae, a pathogen causing invasive neonatal disease." Glaser P., Rusniok C., Buchrieser C., Chevalier F., Frangeul L., Msadek T., Zouine M., Couve E., Lalioui L., Poyart C., Trieu-Cuot P., Kunst F. Mol. Microbiol. 45:1499-1513(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: NEM316.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL766846 Genomic DNA. Translation: CAD46222.1.
RefSeq	NP_735042.1. NC_004368.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	211110.gbs0578.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CAD46222; CAD46222; CAD46222.
GeneID	1031411.
KEGG	san:gbs0578.
PATRIC	19637004. VBIStrAga3577_0594.
Organism-specific databases
GenoList	gbs0578.
CMR	Search...
Phylogenomic databases
eggNOG	COG1481.
HOGENOM	HOG000040187.
KO	K09762.
OMA	DSFFGIE.
ProtClustDB	CLSK877081.
Family and domain databases
HAMAP	MF_01420. HTH-type_WhiA.
InterPro	IPR003802. Sporulation_regulator_WhiA. IPR023054. Sporulation_regulator_WhiA_C. IPR018478. Sporulation_regulator_WhiA_N. [Graphical view]
Pfam	PF02650. HTH_WhiA. 1 hit. PF10298. WhiA_N. 1 hit. [Graphical view]
TIGRFAMs	TIGR00647. MG103. 1 hit.
ProtoNet	Search...

Entry information

Entry name

WHIA_STRA3

Accession

Primary (citable) accession number: Q8E6I5

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 26, 2009
Last sequence update:	March 1, 2003
Last modified:	May 1, 2013
This is version 55 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program