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Q8E4H8 (FENR_STRA3) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 59. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ferredoxin--NADP reductase
Short name=FNR
Short name=Fd-NADP+ reductase
EC=1.18.1.2
Gene names
Ordered Locus Names:gbs1423
OrganismStreptococcus agalactiae serotype III [Complete proteome] [HAMAP]
Taxonomic identifier216495 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Lactobacillales › Streptococcaceae › Streptococcus

Protein attributes

Sequence length330 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

2 reduced ferredoxin + NADP+ + H+ = 2 oxidized ferredoxin + NADPH. HAMAP MF_01685

Cofactor

Binds 1 FAD per subunit By similarity. HAMAP MF_01685

Subunit structure

Homodimer By similarity. HAMAP MF_01685

Sequence similarities

Belongs to the ferredoxin--NADP reductase type 2 family.

Ontologies

Keywords
   LigandFAD
Flavoprotein
NADP
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Molecular functionferredoxin-NADP+ reductase activity

Inferred from electronic annotation. Source: EC

flavin adenine dinucleotide binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 330330Ferredoxin--NADP reductase HAMAP MF_01685
PRO_0000364951

Sites

Binding site351FAD By similarity
Binding site431FAD By similarity
Binding site481FAD By similarity
Binding site901FAD; via amide nitrogen and carbonyl oxygen By similarity
Binding site1231FAD; via amide nitrogen By similarity
Binding site2851FAD By similarity
Binding site3261FAD By similarity

Sequences

Sequence LengthMass (Da)Tools
Q8E4H8 [UniParc].

Last modified March 1, 2003. Version 1.
Checksum: 879B028823786140

FASTA33036,387
        10         20         30         40         50         60 
MNKTIYDITI VGGGPVGLFA AFYAGLRGVS VKIIESLSEL GGQPAILYPE KKIYDIPGYP 

        70         80         90        100        110        120 
VITGRELIDK HIEQLERFKD SIEICLKEEV LSFEKVDDVF TIQTDKDQHL SRAIVFACGN 

       130        140        150        160        170        180 
GAFAPRLLGL ENEENYADNN LFYNVTKLEQ FAGKHVVICG GGDSAVDWAN ELDKIAASVA 

       190        200        210        220        230        240 
IVHRRDAFRA HEHSVDILKA SGVRILTPYV PIGLNGDSQR VSSLVVQKVK GDEVIELPLD 

       250        260        270        280        290        300 
NLIVSFGFST SNKNLRYWNL DYKRSSINVS SLFETTQEGV YAIGDAANYP GKVELIATGY 

       310        320        330 
GEAPVAINQA INYIYPDRDN RVVHSTSLIK

« Hide

References

[1]"Genome sequence of Streptococcus agalactiae, a pathogen causing invasive neonatal disease."
Glaser P., Rusniok C., Buchrieser C., Chevalier F., Frangeul L., Msadek T., Zouine M., Couve E., Lalioui L., Poyart C., Trieu-Cuot P., Kunst F.
Mol. Microbiol. 45:1499-1513(2002) [PubMed: 12354221] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: NEM316 / Serotype III.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AL766850 Genomic DNA. Translation: CAD47082.1.
RefSeqNP_735860.1. NC_004368.1.

3D structure databases

ProteinModelPortalQ8E4H8.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBSTRT00000002402; EBSTRP00000002320; EBSTRG00000002402.
GeneID1030473.
GenomeReviewsGene locus gbs1423 in contig AL732656_GR.
KEGGsan:gbs1423.
PATRIC19638731. VBIStrAga3577_1454.

Organism-specific databases

GenoListgbs1423.
CMRSearch...

Phylogenomic databases

GeneTreeEBGT00050000027206.
HOGENOMHBG669726.
OMAYPNKQKL.
ProtClustDBCLSK698502.

Enzyme and pathway databases

BioCycSAGA211110:GBS1423-MONOMER.

Family and domain databases

HAMAPMF_01685. FENR2.
[Tree]
InterProIPR013027. FAD_pyr_nucl-diS_OxRdtase.
IPR022890. Fd--NADP_Rdtase_type_2.
IPR023753. Pyr_nucl-diS_OxRdtase_FAD/NAD.
IPR001327. Pyr_OxRdtase_NAD-bd_dom.
IPR000103. Pyridine_nuc-diS_OxRdtase_2.
[Graphical view]
KOK00384.
PANTHERPTHR22912:SF53. PTHR22912:SF53. 1 hit.
PfamPF00070. Pyr_redox. 1 hit.
PF07992. Pyr_redox_2. 1 hit.
[Graphical view]
PRINTSPR00368. FADPNR.
PR00469. PNDRDTASEII.
ProtoNetSearch...

Entry information

Entry nameFENR_STRA3
AccessionPrimary (citable) accession number: Q8E4H8
Entry history
Integrated into UniProtKB/Swiss-Prot: March 3, 2009
Last sequence update: March 1, 2003
Last modified: January 25, 2012
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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