Q8E3B1 (TAL_STRA3) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable transaldolase
EC=2.2.1.2

Gene names

Name:	tal
Ordered Locus Names:	gbs1850

Organism

Streptococcus agalactiae serotype III [Complete proteome] [HAMAP]

Taxonomic identifier

216495 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Lactobacillales › Streptococcaceae › Streptococcus

Protein attributes

Sequence length	215 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway By similarity. HAMAP MF_00494
Catalytic activity	Sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + D-fructose 6-phosphate. HAMAP MF_00494
Pathway	Carbohydrate degradation; pentose phosphate pathway; D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage): step 2/3. HAMAP MF_00494
Subcellular location	Cytoplasm By similarity HAMAP MF_00494.
Sequence similarities	Belongs to the transaldolase family. Type 3B subfamily.

Ontologies

Keywords
Biological process	Pentose shunt
Cellular component	Cytoplasm
Molecular function	Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	pentose-phosphate shunt Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 215	215	Probable transaldolase HAMAP MF_00494		PRO_0000173681
Sites
	Active site	83	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q8E3B1 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: AEDE4F44799DB35D	FASTA	215	23,549
	10 20 30 40 50 60 MKYFLDTADV SEIRRLNRLG IVDGVTTNPT IISREGRDFK EVINEICQIV DGPVSAEVTG 70 80 90 100 110 120 LTCDEMVTEA REIAKWSPNV VVKIPMTEEG LAAVSQLSKE GIKTNVTLIF TVAQGLSAMK 130 140 150 160 170 180 AGATFISPFV GRLEDIGTDA YALIRDLRHI IDFYGFQSEI IAASIRGLAH VEGVAKCGAH 190 200 210 IATIPDKTFA SLFTHPLTDK GIETFLKDWD SFKKK

References

[1]	"Genome sequence of Streptococcus agalactiae, a pathogen causing invasive neonatal disease." Glaser P., Rusniok C., Buchrieser C., Chevalier F., Frangeul L., Msadek T., Zouine M., Couve E., Lalioui L., Poyart C., Trieu-Cuot P., Kunst F. Mol. Microbiol. 45:1499-1513(2002) [PubMed: 12354221] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: NEM316 / Serotype III.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL766853 Genomic DNA. Translation: CAD47509.1.
RefSeq	NP_736284.1. NC_004368.1.
3D structure databases
ProteinModelPortal	Q8E3B1.
SMR	Q8E3B1. Positions 1-214.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBSTRT00000003774; EBSTRP00000003692; EBSTRG00000003774.
GeneID	1030936.
GenomeReviews	Gene locus gbs1850 in contig AL732656_GR.
KEGG	san:gbs1850.
PATRIC	19639621. VBIStrAga3577_1897.
Organism-specific databases
GenoList	gbs1850.
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000027173.
HOGENOM	HBG533000.
OMA	HIRRICE.
ProtClustDB	PRK01362.
Enzyme and pathway databases
BioCyc	SAGA211110:GBS1850-MONOMER.
Family and domain databases
HAMAP	MF_00494. Transaldolase_3b. [Tree]
InterPro	IPR013785. Aldolase_TIM. IPR001585. Transaldolase. IPR004731. Transaldolase_3A/3B. IPR022999. Transaldolase_3B. IPR018225. Transaldolase_AS. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KO	K00616.
PANTHER	PTHR10683. Transaldolase. 1 hit.
Pfam	PF00923. Transaldolase. 1 hit. [Graphical view]
TIGRFAMs	TIGR00875. Fsa_talC_mipB. 1 hit.
PROSITE	PS01054. TRANSALDOLASE_1. 1 hit. PS00958. TRANSALDOLASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

TAL_STRA3

Accession

Primary (citable) accession number: Q8E3B1

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 16, 2004
Last sequence update:	March 1, 2003
Last modified:	January 25, 2012
This is version 55 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program