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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Streptococcus agalactiae serotype III (strain NEM316)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:gbs2056
OrganismiStreptococcus agalactiae serotype III (strain NEM316)
Taxonomic identifieri211110 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
Proteomesi
  • UP000000823 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001516131 – 563Arginine--tRNA ligaseAdd BLAST563

Proteomic databases

PRIDEiQ8E2R1

Interactioni

Subunit structurei

Monomer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliQ8E2R1
SMRiQ8E2R1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi121 – 131"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C75 Bacteria
COG0018 LUCA
HOGENOMiHOG000247211
KOiK01887
OMAiNKPLHLG

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.30.1360.70, 1 hit
3.40.50.620, 1 hit
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 1 hit
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit

Sequencei

Sequence statusi: Complete.

Q8E2R1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDTKHLIASE IQKVVPDMEQ STILSLLETP KNSSMGDLAF PAFSLAKTLR
60 70 80 90 100
KAPQIIASDI AEQIKSDQFE KVEAVGPYVN FFLDKAAISS QVLKQVLSDG
110 120 130 140 150
SAYATQNIGE GRNVAIDMSS PNIAKPFSIG HLRSTVIGDS LANIFDKIGY
160 170 180 190 200
HPVKINHLGD WGKQFGMLIV AYKKWGNEEA VRAHPIDELL KLYVRINAEA
210 220 230 240 250
ETDPSVDEEA REWFRKLEAN DPEATELWQW FRDESLLEFN RLYDQMNVTF
260 270 280 290 300
DSYNGEAFYN DKMDEVLELL ESKNLLVESK GAQVVNLEKY GIEHPALIKK
310 320 330 340 350
SDGATLYITR DLAAALYRKR TYDFAKSIYV VGNEQSAHFK QLKAVLKEMD
360 370 380 390 400
YDWSDDMTHV PFGLVTKGGA KLSTRKGNVI LLEPTVAEAI NRAASQIEAK
410 420 430 440 450
NPNLADKDKV AQAVGVGAIK FYDLKTDRTN GYDFDLEAMV SFEGETGPYV
460 470 480 490 500
QYAHARIQSI LRKANFNPSN SDNYSLNDVE SWEIIKLIQD FPRIIVRAAD
510 520 530 540 550
NFEPSIIAKF AINLAQCFNK YYAHTRILDE DAEISSRLAL CYATATVLKE
560
SLRLLGVDAP NEM
Length:563
Mass (Da):63,188
Last modified:March 1, 2003 - v1
Checksum:i50520F4FFA657A77
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL766856 Genomic DNA Translation: CAD47715.1
RefSeqiWP_000379867.1, NC_004368.1

Genome annotation databases

EnsemblBacteriaiCAD47715; CAD47715; CAD47715
KEGGisan:argS

Similar proteinsi

Entry informationi

Entry nameiSYR_STRA3
AccessioniPrimary (citable) accession number: Q8E2R1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 14, 2003
Last sequence update: March 1, 2003
Last modified: May 23, 2018
This is version 93 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

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