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Protein

Uronate isomerase

Gene

uxaC

Organism
Streptococcus agalactiae serotype V (strain ATCC BAA-611 / 2603 V/R)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucuronate = D-fructuronate.UniRule annotation
D-galacturonate = D-tagaturonate.UniRule annotation

Pathwayi: pentose and glucuronate interconversion

This protein is involved in the pathway pentose and glucuronate interconversion, which is part of Carbohydrate metabolism.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway pentose and glucuronate interconversion and in Carbohydrate metabolism.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Enzyme and pathway databases

BioCyciSAGA208435:GHVY-792-MONOMER.
UniPathwayiUPA00246.

Names & Taxonomyi

Protein namesi
Recommended name:
Uronate isomeraseUniRule annotation (EC:5.3.1.12UniRule annotation)
Alternative name(s):
Glucuronate isomeraseUniRule annotation
Uronic isomeraseUniRule annotation
Gene namesi
Name:uxaCUniRule annotation
Ordered Locus Names:SAG0701
OrganismiStreptococcus agalactiae serotype V (strain ATCC BAA-611 / 2603 V/R)
Taxonomic identifieri208435 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
Proteomesi
  • UP000000821 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 466466Uronate isomerasePRO_0000172788Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliQ8E0M9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the uronate isomerase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000224075.
KOiK01812.
OMAiMAWAKTV.
OrthoDBiEOG6J1D95.

Family and domain databases

Gene3Di1.10.2020.10. 1 hit.
HAMAPiMF_00675. UxaC.
InterProiIPR032466. Metal_Hydrolase.
IPR003766. Uronate_isomerase.
IPR023177. Uronate_isomerase_dom2.
[Graphical view]
PfamiPF02614. UxaC. 1 hit.
[Graphical view]
SUPFAMiSSF51556. SSF51556. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8E0M9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAFNTETFML KNQAAIQLYE EVKRQPIFDY HCHLDPKDIF EDHIFDNIVD
60 70 80 90 100
LWLGGDHYKW RLMRANGISE AEITGPASNL EKFKAFARTL ERAYGNPVYH
110 120 130 140 150
WSAMELKNVF GVNEILTESN AEEIYHRLNH FLKEHKISPR RLIADSKVMF
160 170 180 190 200
IGTTDHPLDT LEWHKKLAAD ESFKTVVAPT FRPDEAFIEH RHFVDFITKL
210 220 230 240 250
GDITQKEITD FSTFIAAMEE RIAYFAQNGC RASDISFTEI VFEQTDELEL
260 270 280 290 300
NDLFNKVCEG YIPNQSEISK WQTAVFMELC RLYKKYGFVT QVHFGALRNN
310 320 330 340 350
HSTIFEKLGA DVGVDSLGDQ VALTVNMNRL LDSLVKKDSL PKMIWYNLNP
360 370 380 390 400
AYNIAVANTL ANFQANELGV RSYLQFGAGW WFADTKLGMI SQMNALAEQG
410 420 430 440 450
MLANFIGMLT DSRSFLSYQR HDYFRRILCT YLGEWIEEGE VPEDYQALGS
460
MAKDIAYQNA VNYFKN
Length:466
Mass (Da):53,804
Last modified:March 1, 2003 - v1
Checksum:iF248002E2BADFC41
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE009948 Genomic DNA. Translation: AAM99588.1.
RefSeqiNP_687716.1. NC_004116.1.
WP_000885296.1. NC_004116.1.

Genome annotation databases

EnsemblBacteriaiAAM99588; AAM99588; SAG0701.
GeneIDi1013505.
KEGGisag:SAG0701.
PATRICi19628232. VBIStrAga72745_0707.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE009948 Genomic DNA. Translation: AAM99588.1.
RefSeqiNP_687716.1. NC_004116.1.
WP_000885296.1. NC_004116.1.

3D structure databases

ProteinModelPortaliQ8E0M9.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAM99588; AAM99588; SAG0701.
GeneIDi1013505.
KEGGisag:SAG0701.
PATRICi19628232. VBIStrAga72745_0707.

Phylogenomic databases

HOGENOMiHOG000224075.
KOiK01812.
OMAiMAWAKTV.
OrthoDBiEOG6J1D95.

Enzyme and pathway databases

UniPathwayiUPA00246.
BioCyciSAGA208435:GHVY-792-MONOMER.

Family and domain databases

Gene3Di1.10.2020.10. 1 hit.
HAMAPiMF_00675. UxaC.
InterProiIPR032466. Metal_Hydrolase.
IPR003766. Uronate_isomerase.
IPR023177. Uronate_isomerase_dom2.
[Graphical view]
PfamiPF02614. UxaC. 1 hit.
[Graphical view]
SUPFAMiSSF51556. SSF51556. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-611 / 2603 V/R.

Entry informationi

Entry nameiUXAC_STRA5
AccessioniPrimary (citable) accession number: Q8E0M9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 11, 2003
Last sequence update: March 1, 2003
Last modified: November 11, 2015
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.