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Q8E0M8

- UXUA_STRA5

UniProt

Q8E0M8 - UXUA_STRA5

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Protein

Mannonate dehydratase

Gene

uxuA

Organism
Streptococcus agalactiae serotype V (strain ATCC BAA-611 / 2603 V/R)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the dehydration of D-mannonate.UniRule annotation

Catalytic activityi

D-mannonate = 2-dehydro-3-deoxy-D-gluconate + H2O.UniRule annotation

Cofactori

Fe2+ or Mn2+ ion.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. mannonate dehydratase activity Source: UniProtKB-EC

GO - Biological processi

  1. glucuronate catabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Lyase

Keywords - Ligandi

Iron, Manganese

Enzyme and pathway databases

BioCyciSAGA208435:GHVY-793-MONOMER.
UniPathwayiUPA00246.

Names & Taxonomyi

Protein namesi
Recommended name:
Mannonate dehydrataseUniRule annotation (EC:4.2.1.8UniRule annotation)
Alternative name(s):
D-mannonate hydro-lyaseUniRule annotation
Gene namesi
Name:uxuAUniRule annotation
Ordered Locus Names:SAG0702
OrganismiStreptococcus agalactiae serotype V (strain ATCC BAA-611 / 2603 V/R)
Taxonomic identifieri208435 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
ProteomesiUP000000821: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 348348Mannonate dehydratasePRO_0000170688Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi208435.SAG0702.

Structurei

3D structure databases

ProteinModelPortaliQ8E0M8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the mannonate dehydratase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG1312.
HOGENOMiHOG000195381.
KOiK01686.
OMAiDFYESAH.
OrthoDBiEOG6ZSP6Z.

Family and domain databases

Gene3Di3.20.20.150. 1 hit.
HAMAPiMF_00106. UxuA.
InterProiIPR004628. Man_deHydtase.
IPR013022. Xyl_isomerase-like_TIM-brl.
[Graphical view]
PfamiPF03786. UxuA. 1 hit.
[Graphical view]
PIRSFiPIRSF016049. Man_dehyd. 1 hit.
SUPFAMiSSF51658. SSF51658. 1 hit.
TIGRFAMsiTIGR00695. uxuA. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8E0M8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MEMSFRWYGE DDPVTLENIG QIPTMKGIVT AIYDVPVGEV WSRERIQQLK
60 70 80 90 100
EKVEAAGLKI SVIESVPVHE DIKLGRPTRD LLIDNYIQTV KNLAAEGIDT
110 120 130 140 150
ICYNFMPVFD WTRTDLAYQY PDGSTALIFD ETVSKKMDPV NGELSLPGWD
160 170 180 190 200
ASYSKEEMKA IMDAYAEIDE EKLWENLTYF IKRIIPEAEA VGVKMAIHPD
210 220 230 240 250
DPPYSIFGLP RIITGLEAIE RFVKLYDSKS NGITLCVGSY ASDPQNDVLE
260 270 280 290 300
ISRRAFELDR VNFVHARNIK LGDGKSFKES AHPSEYGSID MYEVIKLCHE
310 320 330 340
FGFEGAIRPD HGRMIWGETG RPGYGLYDRA LGATYVSGLY EAVIKGSK
Length:348
Mass (Da):39,249
Last modified:March 1, 2003 - v1
Checksum:i2D135E69BB3BC4DA
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE009948 Genomic DNA. Translation: AAM99589.1.
RefSeqiNP_687717.1. NC_004116.1.

Genome annotation databases

EnsemblBacteriaiAAM99589; AAM99589; SAG0702.
GeneIDi1013506.
KEGGisag:SAG0702.
PATRICi19628234. VBIStrAga72745_0708.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE009948 Genomic DNA. Translation: AAM99589.1 .
RefSeqi NP_687717.1. NC_004116.1.

3D structure databases

ProteinModelPortali Q8E0M8.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 208435.SAG0702.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAM99589 ; AAM99589 ; SAG0702 .
GeneIDi 1013506.
KEGGi sag:SAG0702.
PATRICi 19628234. VBIStrAga72745_0708.

Phylogenomic databases

eggNOGi COG1312.
HOGENOMi HOG000195381.
KOi K01686.
OMAi DFYESAH.
OrthoDBi EOG6ZSP6Z.

Enzyme and pathway databases

UniPathwayi UPA00246 .
BioCyci SAGA208435:GHVY-793-MONOMER.

Family and domain databases

Gene3Di 3.20.20.150. 1 hit.
HAMAPi MF_00106. UxuA.
InterProi IPR004628. Man_deHydtase.
IPR013022. Xyl_isomerase-like_TIM-brl.
[Graphical view ]
Pfami PF03786. UxuA. 1 hit.
[Graphical view ]
PIRSFi PIRSF016049. Man_dehyd. 1 hit.
SUPFAMi SSF51658. SSF51658. 1 hit.
TIGRFAMsi TIGR00695. uxuA. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-611 / 2603 V/R.

Entry informationi

Entry nameiUXUA_STRA5
AccessioniPrimary (citable) accession number: Q8E0M8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 11, 2003
Last sequence update: March 1, 2003
Last modified: October 1, 2014
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3