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Q8E0M8

- UXUA_STRA5

UniProt

Q8E0M8 - UXUA_STRA5

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Protein

Mannonate dehydratase

Gene
uxuA, SAG0702
Organism
Streptococcus agalactiae serotype V (strain ATCC BAA-611 / 2603 V/R)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the dehydration of D-mannonate By similarity.UniRule annotation

Catalytic activityi

D-mannonate = 2-dehydro-3-deoxy-D-gluconate + H2O.UniRule annotation

Cofactori

Fe2+ or Mn2+ ion By similarity.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. mannonate dehydratase activity Source: UniProtKB-EC

GO - Biological processi

  1. glucuronate catabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Lyase

Keywords - Ligandi

Iron, Manganese

Enzyme and pathway databases

BioCyciSAGA208435:GHVY-793-MONOMER.
UniPathwayiUPA00246.

Names & Taxonomyi

Protein namesi
Recommended name:
Mannonate dehydratase (EC:4.2.1.8)
Alternative name(s):
D-mannonate hydro-lyase
Gene namesi
Name:uxuA
Ordered Locus Names:SAG0702
OrganismiStreptococcus agalactiae serotype V (strain ATCC BAA-611 / 2603 V/R)
Taxonomic identifieri208435 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
ProteomesiUP000000821: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 348348Mannonate dehydrataseUniRule annotationPRO_0000170688Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi208435.SAG0702.

Structurei

3D structure databases

ProteinModelPortaliQ8E0M8.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG1312.
HOGENOMiHOG000195381.
KOiK01686.
OMAiDFYESAH.
OrthoDBiEOG6ZSP6Z.

Family and domain databases

Gene3Di3.20.20.150. 1 hit.
HAMAPiMF_00106. UxuA.
InterProiIPR004628. Man_deHydtase.
IPR013022. Xyl_isomerase-like_TIM-brl.
[Graphical view]
PfamiPF03786. UxuA. 1 hit.
[Graphical view]
PIRSFiPIRSF016049. Man_dehyd. 1 hit.
SUPFAMiSSF51658. SSF51658. 1 hit.
TIGRFAMsiTIGR00695. uxuA. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8E0M8-1 [UniParc]FASTAAdd to Basket

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MEMSFRWYGE DDPVTLENIG QIPTMKGIVT AIYDVPVGEV WSRERIQQLK    50
EKVEAAGLKI SVIESVPVHE DIKLGRPTRD LLIDNYIQTV KNLAAEGIDT 100
ICYNFMPVFD WTRTDLAYQY PDGSTALIFD ETVSKKMDPV NGELSLPGWD 150
ASYSKEEMKA IMDAYAEIDE EKLWENLTYF IKRIIPEAEA VGVKMAIHPD 200
DPPYSIFGLP RIITGLEAIE RFVKLYDSKS NGITLCVGSY ASDPQNDVLE 250
ISRRAFELDR VNFVHARNIK LGDGKSFKES AHPSEYGSID MYEVIKLCHE 300
FGFEGAIRPD HGRMIWGETG RPGYGLYDRA LGATYVSGLY EAVIKGSK 348
Length:348
Mass (Da):39,249
Last modified:March 1, 2003 - v1
Checksum:i2D135E69BB3BC4DA
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE009948 Genomic DNA. Translation: AAM99589.1.
RefSeqiNP_687717.1. NC_004116.1.

Genome annotation databases

EnsemblBacteriaiAAM99589; AAM99589; SAG0702.
GeneIDi1013506.
KEGGisag:SAG0702.
PATRICi19628234. VBIStrAga72745_0708.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE009948 Genomic DNA. Translation: AAM99589.1 .
RefSeqi NP_687717.1. NC_004116.1.

3D structure databases

ProteinModelPortali Q8E0M8.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 208435.SAG0702.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAM99589 ; AAM99589 ; SAG0702 .
GeneIDi 1013506.
KEGGi sag:SAG0702.
PATRICi 19628234. VBIStrAga72745_0708.

Phylogenomic databases

eggNOGi COG1312.
HOGENOMi HOG000195381.
KOi K01686.
OMAi DFYESAH.
OrthoDBi EOG6ZSP6Z.

Enzyme and pathway databases

UniPathwayi UPA00246 .
BioCyci SAGA208435:GHVY-793-MONOMER.

Family and domain databases

Gene3Di 3.20.20.150. 1 hit.
HAMAPi MF_00106. UxuA.
InterProi IPR004628. Man_deHydtase.
IPR013022. Xyl_isomerase-like_TIM-brl.
[Graphical view ]
Pfami PF03786. UxuA. 1 hit.
[Graphical view ]
PIRSFi PIRSF016049. Man_dehyd. 1 hit.
SUPFAMi SSF51658. SSF51658. 1 hit.
TIGRFAMsi TIGR00695. uxuA. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-611 / 2603 V/R.

Entry informationi

Entry nameiUXUA_STRA5
AccessioniPrimary (citable) accession number: Q8E0M8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 11, 2003
Last sequence update: March 1, 2003
Last modified: May 14, 2014
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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