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Q8E0A8

- URK_STRA5

UniProt

Q8E0A8 - URK_STRA5

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Protein

Uridine kinase

Gene

udk

Organism
Streptococcus agalactiae serotype V (strain ATCC BAA-611 / 2603 V/R)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + uridine = ADP + UMP.UniRule annotation
ATP + cytidine = ADP + CMP.UniRule annotation

Pathwayi

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi12 – 198ATPUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. phosphotransferase activity, alcohol group as acceptor Source: InterPro
  3. uridine kinase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. CTP salvage Source: UniProtKB-UniPathway
  2. UMP salvage Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciSAGA208435:GHVY-917-MONOMER.
UniPathwayiUPA00574; UER00637.
UPA00579; UER00640.

Names & Taxonomyi

Protein namesi
Recommended name:
Uridine kinaseUniRule annotation (EC:2.7.1.48UniRule annotation)
Alternative name(s):
Cytidine monophosphokinaseUniRule annotation
Uridine monophosphokinaseUniRule annotation
Gene namesi
Name:udkUniRule annotation
Ordered Locus Names:SAG0826
OrganismiStreptococcus agalactiae serotype V (strain ATCC BAA-611 / 2603 V/R)
Taxonomic identifieri208435 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
ProteomesiUP000000821: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 209209Uridine kinasePRO_1000017907Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi208435.SAG0826.

Structurei

3D structure databases

ProteinModelPortaliQ8E0A8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the uridine kinase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0572.
HOGENOMiHOG000262756.
KOiK00876.
OMAiEGVIDQY.
OrthoDBiEOG6KMBCH.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00551. Uridine_kinase.
InterProiIPR027417. P-loop_NTPase.
IPR006083. PRK/URK.
IPR026008. Uridine_kinase_.
IPR000764. Uridine_kinase_like.
[Graphical view]
PANTHERiPTHR10285:SF6. PTHR10285:SF6. 1 hit.
PfamiPF00485. PRK. 1 hit.
[Graphical view]
PRINTSiPR00988. URIDINKINASE.
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00235. udk. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8E0A8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MRKKPIIIGV TGGSGGGKTS VSRAILSNFP DQKITMIEHD SYYKDQSHLT
60 70 80 90 100
FEERVKTNYD HPLAFDTNLM IEQLNELIEG RPVDIPVYDY TKHTRSDRTI
110 120 130 140 150
RQEPQDVIIV EGILVLEDQR LRDLMDIKLF VDTDDDIRII RRIKRDMEER
160 170 180 190 200
DRSLDSIIEQ YTEVVKPMYH QFIEPTKRYA DIVIPEGVSN IVAIDLINTK

VASILNEAK
Length:209
Mass (Da):24,217
Last modified:March 1, 2003 - v1
Checksum:i79253A0FFADDABD2
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE009948 Genomic DNA. Translation: AAM99713.1.
RefSeqiNP_687841.1. NC_004116.1.

Genome annotation databases

EnsemblBacteriaiAAM99713; AAM99713; SAG0826.
GeneIDi1013630.
KEGGisag:SAG0826.
PATRICi19628482. VBIStrAga72745_0832.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE009948 Genomic DNA. Translation: AAM99713.1 .
RefSeqi NP_687841.1. NC_004116.1.

3D structure databases

ProteinModelPortali Q8E0A8.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 208435.SAG0826.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAM99713 ; AAM99713 ; SAG0826 .
GeneIDi 1013630.
KEGGi sag:SAG0826.
PATRICi 19628482. VBIStrAga72745_0832.

Phylogenomic databases

eggNOGi COG0572.
HOGENOMi HOG000262756.
KOi K00876.
OMAi EGVIDQY.
OrthoDBi EOG6KMBCH.

Enzyme and pathway databases

UniPathwayi UPA00574 ; UER00637 .
UPA00579 ; UER00640 .
BioCyci SAGA208435:GHVY-917-MONOMER.

Family and domain databases

Gene3Di 3.40.50.300. 1 hit.
HAMAPi MF_00551. Uridine_kinase.
InterProi IPR027417. P-loop_NTPase.
IPR006083. PRK/URK.
IPR026008. Uridine_kinase_.
IPR000764. Uridine_kinase_like.
[Graphical view ]
PANTHERi PTHR10285:SF6. PTHR10285:SF6. 1 hit.
Pfami PF00485. PRK. 1 hit.
[Graphical view ]
PRINTSi PR00988. URIDINKINASE.
SUPFAMi SSF52540. SSF52540. 1 hit.
TIGRFAMsi TIGR00235. udk. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-611 / 2603 V/R.

Entry informationi

Entry nameiURK_STRA5
AccessioniPrimary (citable) accession number: Q8E0A8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: March 1, 2003
Last modified: October 29, 2014
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3