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Q8E0A8

- URK_STRA5

UniProt

Q8E0A8 - URK_STRA5

Protein

Uridine kinase

Gene

udk

Organism
Streptococcus agalactiae serotype V (strain ATCC BAA-611 / 2603 V/R)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 74 (01 Oct 2014)
      Sequence version 1 (01 Mar 2003)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + uridine = ADP + UMP.UniRule annotation
    ATP + cytidine = ADP + CMP.UniRule annotation

    Pathwayi

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi12 – 198ATPUniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-HAMAP
    2. phosphotransferase activity, alcohol group as acceptor Source: InterPro
    3. uridine kinase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. CTP salvage Source: UniProtKB-UniPathway
    2. UMP salvage Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Kinase, Transferase

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciSAGA208435:GHVY-917-MONOMER.
    UniPathwayiUPA00574; UER00637.
    UPA00579; UER00640.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Uridine kinaseUniRule annotation (EC:2.7.1.48UniRule annotation)
    Alternative name(s):
    Cytidine monophosphokinaseUniRule annotation
    Uridine monophosphokinaseUniRule annotation
    Gene namesi
    Name:udkUniRule annotation
    Ordered Locus Names:SAG0826
    OrganismiStreptococcus agalactiae serotype V (strain ATCC BAA-611 / 2603 V/R)
    Taxonomic identifieri208435 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
    ProteomesiUP000000821: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 209209Uridine kinasePRO_1000017907Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi208435.SAG0826.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8E0A8.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the uridine kinase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0572.
    HOGENOMiHOG000262756.
    KOiK00876.
    OMAiEGVIDQY.
    OrthoDBiEOG6KMBCH.

    Family and domain databases

    Gene3Di3.40.50.300. 1 hit.
    HAMAPiMF_00551. Uridine_kinase.
    InterProiIPR027417. P-loop_NTPase.
    IPR006083. PRK/URK.
    IPR026008. Uridine_kinase_.
    IPR000764. Uridine_kinase_like.
    [Graphical view]
    PANTHERiPTHR10285:SF6. PTHR10285:SF6. 1 hit.
    PfamiPF00485. PRK. 1 hit.
    [Graphical view]
    PRINTSiPR00988. URIDINKINASE.
    SUPFAMiSSF52540. SSF52540. 1 hit.
    TIGRFAMsiTIGR00235. udk. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q8E0A8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MRKKPIIIGV TGGSGGGKTS VSRAILSNFP DQKITMIEHD SYYKDQSHLT    50
    FEERVKTNYD HPLAFDTNLM IEQLNELIEG RPVDIPVYDY TKHTRSDRTI 100
    RQEPQDVIIV EGILVLEDQR LRDLMDIKLF VDTDDDIRII RRIKRDMEER 150
    DRSLDSIIEQ YTEVVKPMYH QFIEPTKRYA DIVIPEGVSN IVAIDLINTK 200
    VASILNEAK 209
    Length:209
    Mass (Da):24,217
    Last modified:March 1, 2003 - v1
    Checksum:i79253A0FFADDABD2
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE009948 Genomic DNA. Translation: AAM99713.1.
    RefSeqiNP_687841.1. NC_004116.1.

    Genome annotation databases

    EnsemblBacteriaiAAM99713; AAM99713; SAG0826.
    GeneIDi1013630.
    KEGGisag:SAG0826.
    PATRICi19628482. VBIStrAga72745_0832.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE009948 Genomic DNA. Translation: AAM99713.1 .
    RefSeqi NP_687841.1. NC_004116.1.

    3D structure databases

    ProteinModelPortali Q8E0A8.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 208435.SAG0826.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAM99713 ; AAM99713 ; SAG0826 .
    GeneIDi 1013630.
    KEGGi sag:SAG0826.
    PATRICi 19628482. VBIStrAga72745_0832.

    Phylogenomic databases

    eggNOGi COG0572.
    HOGENOMi HOG000262756.
    KOi K00876.
    OMAi EGVIDQY.
    OrthoDBi EOG6KMBCH.

    Enzyme and pathway databases

    UniPathwayi UPA00574 ; UER00637 .
    UPA00579 ; UER00640 .
    BioCyci SAGA208435:GHVY-917-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.300. 1 hit.
    HAMAPi MF_00551. Uridine_kinase.
    InterProi IPR027417. P-loop_NTPase.
    IPR006083. PRK/URK.
    IPR026008. Uridine_kinase_.
    IPR000764. Uridine_kinase_like.
    [Graphical view ]
    PANTHERi PTHR10285:SF6. PTHR10285:SF6. 1 hit.
    Pfami PF00485. PRK. 1 hit.
    [Graphical view ]
    PRINTSi PR00988. URIDINKINASE.
    SUPFAMi SSF52540. SSF52540. 1 hit.
    TIGRFAMsi TIGR00235. udk. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC BAA-611 / 2603 V/R.

    Entry informationi

    Entry nameiURK_STRA5
    AccessioniPrimary (citable) accession number: Q8E0A8
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 15, 2008
    Last sequence update: March 1, 2003
    Last modified: October 1, 2014
    This is version 74 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3