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Q8E081 (GLGB_STRA5) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 83. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
1,4-alpha-glucan branching enzyme GlgB

EC=2.4.1.18
Alternative name(s):
1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase
Alpha-(1->4)-glucan branching enzyme
Glycogen branching enzyme
Short name=BE
Gene names
Name:glgB
Ordered Locus Names:SAG0853
OrganismStreptococcus agalactiae serotype V (strain ATCC BAA-611 / 2603 V/R) [Complete proteome] [HAMAP]
Taxonomic identifier208435 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus

Protein attributes

Sequence length622 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position By similarity. HAMAP-Rule MF_00685

Catalytic activity

Transfers a segment of a (1->4)-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain. HAMAP-Rule MF_00685

Pathway

Glycan biosynthesis; glycogen biosynthesis. HAMAP-Rule MF_00685

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00685

Sequence similarities

Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 6226221,4-alpha-glucan branching enzyme GlgB HAMAP-Rule MF_00685
PRO_0000188745

Sites

Active site3001Nucleophile By similarity
Active site3511Proton donor By similarity

Sequences

Sequence LengthMass (Da)Tools
Q8E081 [UniParc].

Last modified March 1, 2003. Version 1.
Checksum: 9533F1F3EADB5D26

FASTA62273,342
        10         20         30         40         50         60 
MSNKDELYTF GIGENFHLQN YLGVHSENGS FCFRVWAPNA ENVQVIGDFT DWRNRPLQMN 

        70         80         90        100        110        120 
KNQAGVWEAN SLDAREGDLY KYLVTRKGGQ VVEKIDPMAV YMERRPGTAS VIKVLRNKKW 

       130        140        150        160        170        180 
EDGLWMGRRK RLGFQKRPIN IYEVHAGSWK KDDFGHPMTF SQLKDYLIPY LVEMNYTHVE 

       190        200        210        220        230        240 
FMPLMAHPLD MSWGYQLMGY FAFEHTYGTP EEFQDFVEAC HKNNIGVLVD WVPGHFIQND 

       250        260        270        280        290        300 
DALAYFDGTA TYEYQNHDRA HNYRWGALNF DLGKNQVQSF LISSALFWIE HYHIDGIRVD 

       310        320        330        340        350        360 
AVSNMLYLDY DEGPWEANQF GDNRNLEGYH FLRKLNKVIK ERHPNVMMIA EESTASTPIT 

       370        380        390        400        410        420 
KDLESGGLGF DFKWNMGWMN DILRFYEEDP LYRQYDFNLV TFSFMYIFNE NFVLAFSHDE 

       430        440        450        460        470        480 
VVHGKKSMMH KMWGDRYNQF AGLRNLYAYQ MCHPGKKLLF MGSEFGQFLE WKYNDQLEWE 

       490        500        510        520        530        540 
NLNDDMNQKM QRYTKQLNQF YKDHKCLWRI DDSFDGLEII DADNKSETVL SFIRKDDKGD 

       550        560        570        580        590        600 
LLLCVFNMTP VERPNFTIGV PQAGIYEEVL NTEMEEFGGV WKNHNPVTKT QVATWKDYDH 

       610        620 
TLSFTLPALG ASVWRIKRRL RK 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE009948 Genomic DNA. Translation: AAM99740.1.
RefSeqNP_687868.1. NC_004116.1.

3D structure databases

ProteinModelPortalQ8E081.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING208435.SAG0853.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAM99740; AAM99740; SAG0853.
GeneID1013657.
KEGGsag:SAG0853.
PATRIC19628536. VBIStrAga72745_0859.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0296.
HOGENOMHOG000283037.
KOK00700.
OMAPIGVAYK.
OrthoDBEOG6JX7GT.

Enzyme and pathway databases

BioCycSAGA208435:GHVY-944-MONOMER.
UniPathwayUPA00164.

Family and domain databases

Gene3D2.60.40.10. 1 hit.
2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
HAMAPMF_00685. GlgB.
InterProIPR006048. A-amylase_b_C.
IPR006407. GlgB.
IPR015902. Glyco_hydro_13.
IPR013780. Glyco_hydro_13_b.
IPR006047. Glyco_hydro_13_cat_dom.
IPR004193. Glyco_hydro_13_N.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
[Graphical view]
PANTHERPTHR10357. PTHR10357. 1 hit.
PfamPF00128. Alpha-amylase. 2 hits.
PF02806. Alpha-amylase_C. 1 hit.
PF02922. CBM_48. 1 hit.
[Graphical view]
PIRSFPIRSF000463. GlgB. 1 hit.
SUPFAMSSF51445. SSF51445. 1 hit.
SSF81296. SSF81296. 1 hit.
TIGRFAMsTIGR01515. branching_enzym. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGLGB_STRA5
AccessionPrimary (citable) accession number: Q8E081
Entry history
Integrated into UniProtKB/Swiss-Prot: August 15, 2003
Last sequence update: March 1, 2003
Last modified: June 11, 2014
This is version 83 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries