Q8DZ08 (Q8DZ08_STRA5) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Dihydrofolate reductase EMBL AAN00185.1

Gene names

Name:	folA EMBL AAN00185.1
Ordered Locus Names:	SAG1314

Organism

Streptococcus agalactiae serotype V [Complete proteome] [HAMAP]

Taxonomic identifier

216466 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Lactobacillales › Streptococcaceae › Streptococcus

Protein attributes

Sequence length	164 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the dihydrofolate reductase family. RuleBase RU004474

Ontologies

Keywords
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycine biosynthetic process Inferred from electronic annotation. Source: InterPro nucleotide biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	NADP binding Inferred from electronic annotation. Source: InterPro dihydrofolate reductase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8DZ08 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: 06BD1D9B85DA724A	FASTA	164	18,943
	10 20 30 40 50 60 MTKQIIAIWA EDEDHLIGVN GGLPWRLPKE LHHFKETTMG QALLMGRKTF DGMNRRVLPG 70 80 90 100 110 120 RETIILTKDE QFQADGVTVL NSVEQVIKWF QEHNKTLFIV GGASIYKAFL PYCEAIIKTK 130 140 150 160 VHGKFKGDTY FPDVNLSEFK VISRDYFEKD EQNAHAFTVT YFEK

References

[1]

"Complete genome sequence and comparative genomic analysis of an emerging human pathogen, serotype V Streptococcus agalactiae." Tettelin H., Masignani V., Cieslewicz M.J., Eisen J.A., Peterson S.N., Wessels M.R., Paulsen I.T., Nelson K.E., Margarit I., Read T.D., Madoff L.C., Wolf A.M., Beanan M.J., Brinkac L.M., Daugherty S.C., DeBoy R.T., Durkin A.S., Kolonay J.F. , Madupu R., Lewis M.R., Radune D., Fedorova N.B., Scanlan D., Khouri H.M., Mulligan S., Carty H.A., Cline R.T., Van Aken S.E., Gill J., Scarselli M., Mora M., Iacobini E.T., Brettoni C., Galli G., Mariani M., Vegni F., Maione D., Rinaudo D., Rappuoli R., Telford J.L., Kasper D.L., Grandi G., Fraser C.M. Proc. Natl. Acad. Sci. U.S.A. 99:12391-12396(2002) [PubMed: 12200547] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-611 / 2603 V/R / Serotype V.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE009948 Genomic DNA. Translation: AAN00185.1.
RefSeq	NP_688312.1. NC_004116.1.
3D structure databases
HSSP	HSSP built from PDB template 1DIU based on UniProtKB P00381.
ProteinModelPortal	Q8DZ08.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBSTRT00000006194; EBSTRP00000005861; EBSTRG00000006194.
GeneID	1014121.
GenomeReviews	Gene locus SAG1314 in contig AE009948_GR.
KEGG	sag:SAG1314.
PATRIC	19629469. VBIStrAga72745_1322.
TIGR	SAG1314.
Phylogenomic databases
GeneTree	EBGT00050000027355.
HOGENOM	HBG665708.
OMA	QDEEGVI.
ProtClustDB	CLSK813711.
Enzyme and pathway databases
BioCyc	SAGA208435:SAG_1314-MONOMER.
Family and domain databases
InterPro	IPR012259. DHFR. IPR024072. DHFR-like_dom. IPR017925. DHFR_CS. IPR001796. DHFR_dom. [Graphical view]
Gene3D	G3DSA:3.40.430.10. G3DSA:3.40.430.10. 1 hit.
KO	K00287.
PANTHER	PTHR11549:SF1. DHFR. 1 hit.
Pfam	PF00186. DHFR_1. 1 hit. [Graphical view]
PIRSF	PIRSF000194. DHFR. 1 hit.
PRINTS	PR00070. DHFR.
SUPFAM	SSF53597. SSF53597. 1 hit.
PROSITE	PS00075. DHFR_1. 1 hit. PS51330. DHFR_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q8DZ08_STRA5

Accession

Primary (citable) accession number: Q8DZ08

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2003
Last sequence update:	March 1, 2003
Last modified:	January 25, 2012
This is version 48 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)