Q8DY14 (Q8DY14_STRA5) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Shikimate 5-dehydrogenase EMBL AAN00544.1

Gene names

Name:	aroE EMBL AAN00544.1
Ordered Locus Names:	SAG1680

Organism

Streptococcus agalactiae serotype V [Complete proteome] [HAMAP]

Taxonomic identifier

216466 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Lactobacillales › Streptococcaceae › Streptococcus

Protein attributes

Sequence length	292 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Shikimate + NADP+ = 3-dehydroshikimate + NADPH. SAAS SAAS011342
Pathway	Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 4/7. SAAS SAAS011342

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis SAAS SAAS011342
Ligand	NADP SAAS SAAS011342
Molecular function	Oxidoreductase RuleBase RU004037 SAAS SAAS011342
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	aromatic amino acid family biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	NADP binding Inferred from electronic annotation. Source: InterPro shikimate 3-dehydrogenase (NADP+) activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8DY14 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: 8533FE4D58A7EF47	FASTA	292	31,966
	10 20 30 40 50 60 MNSLNGETLL TGLIANPARH SLSPLMWNTS FQEKNMNYAY LTFEVEEGKL TEAVRGVRAL 70 80 90 100 110 120 GIRGVNVSMP FKQSVIPLLD DLSPQAKLVG AVNTIVNQGG TGRLVGHMTD GIGCFKALAA 130 140 150 160 170 180 QGFSAKNKII TIAGIGGSGK AVAVQAAMEG VAEIRLFNRN SSNYDKVIDL SDKIKKQFQI 190 200 210 220 230 240 KVVVDYLENK TAFKDAIRTS HFYIDATSLG MRPLDNYSLI NDPEILTPNL VVVDLVYKPK 250 260 270 280 290 ETALLRFVRQ NGVKHAYNGL GMLIYQGAEA FQLITNQEMP ISSVERVLQT EN

References

[1]

"Complete genome sequence and comparative genomic analysis of an emerging human pathogen, serotype V Streptococcus agalactiae." Tettelin H., Masignani V., Cieslewicz M.J., Eisen J.A., Peterson S.N., Wessels M.R., Paulsen I.T., Nelson K.E., Margarit I., Read T.D., Madoff L.C., Wolf A.M., Beanan M.J., Brinkac L.M., Daugherty S.C., DeBoy R.T., Durkin A.S., Kolonay J.F. , Madupu R., Lewis M.R., Radune D., Fedorova N.B., Scanlan D., Khouri H.M., Mulligan S., Carty H.A., Cline R.T., Van Aken S.E., Gill J., Scarselli M., Mora M., Iacobini E.T., Brettoni C., Galli G., Mariani M., Vegni F., Maione D., Rinaudo D., Rappuoli R., Telford J.L., Kasper D.L., Grandi G., Fraser C.M. Proc. Natl. Acad. Sci. U.S.A. 99:12391-12396(2002) [PubMed: 12200547] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-611 / 2603 V/R / Serotype V.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE009948 Genomic DNA. Translation: AAN00544.1.
RefSeq	NP_688671.1. NC_004116.1.
3D structure databases
HSSP	HSSP built from PDB template 1VI2 based on UniProtKB P28244.
ProteinModelPortal	Q8DY14.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBSTRT00000007426; EBSTRP00000007093; EBSTRG00000007426.
GeneID	1014489.
GenomeReviews	Gene locus SAG1680 in contig AE009948_GR.
KEGG	sag:SAG1680.
PATRIC	19630209. VBIStrAga72745_1689.
TIGR	SAG1680.
Phylogenomic databases
GeneTree	EBGT00050000027337.
HOGENOM	HBG553408.
OMA	SIYIDAT.
ProtClustDB	CLSK2297835.
Enzyme and pathway databases
BioCyc	SAGA208435:SAG_1680-MONOMER.
Family and domain databases
HAMAP	MF_00222. Shikimate_DH_AroE. [Tree]
InterPro	IPR016040. NAD(P)-bd_dom. IPR011342. Shikimate_DH. IPR013708. Shikimate_DH-bd_N. IPR022893. Shikimate_quinate_DH. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KO	K00014.
Pfam	PF08501. Shikimate_dh_N. 1 hit. [Graphical view]
TIGRFAMs	TIGR00507. AroE. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q8DY14_STRA5

Accession

Primary (citable) accession number: Q8DY14

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2003
Last sequence update:	March 1, 2003
Last modified:	December 14, 2011
This is version 63 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)