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Protein

Sensor protein DltS

Gene

dltS

Organism
Streptococcus agalactiae serotype V (strain ATCC BAA-611 / 2603 V/R)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Member of the two-component regulatory system DltS/DltR. Regulates the expression of the dlt operon. Probably phosphorylates DltR (By similarity).By similarity

Catalytic activityi

ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.

GO - Molecular functioni

Keywordsi

Molecular functionKinase, Transferase
Biological processTwo-component regulatory system
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Sensor protein DltS (EC:2.7.13.3)
Gene namesi
Name:dltS
Ordered Locus Names:SAG1791
OrganismiStreptococcus agalactiae serotype V (strain ATCC BAA-611 / 2603 V/R)
Taxonomic identifieri208435 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
Proteomesi
  • UP000000821 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei9 – 29HelicalSequence analysisAdd BLAST21
Transmembranei136 – 156HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000747311 – 395Sensor protein DltSAdd BLAST395

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei180Phosphohistidine; by autocatalysisPROSITE-ProRule annotation1

Keywords - PTMi

Phosphoprotein

Structurei

3D structure databases

ProteinModelPortaliQ8DXQ8.
SMRiQ8DXQ8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini177 – 387Histidine kinasePROSITE-ProRule annotationAdd BLAST211

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

HOGENOMiHOG000112224.
OMAiFVLINMS.

Family and domain databases

CDDicd00075. HATPase_c. 1 hit.
cd00082. HisKA. 1 hit.
Gene3Di3.30.565.10. 1 hit.
InterProiView protein in InterPro
IPR003594. HATPase_C.
IPR036890. HATPase_C_sf.
IPR005467. His_kinase_dom.
IPR003661. HisK_dim/P.
IPR036097. HisK_dim/P_sf.
PfamiView protein in Pfam
PF02518. HATPase_c. 1 hit.
PF00512. HisKA. 1 hit.
SMARTiView protein in SMART
SM00387. HATPase_c. 1 hit.
SM00388. HisKA. 1 hit.
SUPFAMiSSF47384. SSF47384. 1 hit.
SSF55874. SSF55874. 1 hit.
PROSITEiView protein in PROSITE
PS50109. HIS_KIN. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8DXQ8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFSDLRKKFV FLTMSILIVV VLFLFAVSNR YNQYWDEYDA YRIVKLVAKN
60 70 80 90 100
DYLGIPGDEP IALVTIDNQK MVKIQSNNTD LTNDVIEKSS LKLLEQGKKS
110 120 130 140 150
RKWKSFIYSI KEYKDKTYTI AIMDLASYEV PYARRFLILV FTIFGFCLLA
160 170 180 190 200
AVSLYLSRFI VGPVETEMTR EKQFVSDASH ELKTPIAAIR ANVQVLEQQI
210 220 230 240 250
PGNRYLDHVV SETKRMEFLI EDLLNLSRLD EKRSKVNFKK LNLSVLCQEV
260 270 280 290 300
LLTYESLAYE EEKCLNDTIE DDVWIVGEES QIKQILIILL DNAIRHSLSK
310 320 330 340 350
SAIQFSLKQA RRKAILTISN PSAIYSKEVM DNLFERFYQA KDDHADSLSF
360 370 380 390
GLGLSIAKAI VERHKGRIRA YQEKDQLRLE VQLPIDGFWT NTMIN
Length:395
Mass (Da):45,764
Last modified:March 1, 2003 - v1
Checksum:i6FEDFE55E5A2CC15
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE009948 Genomic DNA. Translation: AAN00654.1.
RefSeqiNP_688781.1. NC_004116.1.
WP_000490535.1. NC_004116.1.

Genome annotation databases

EnsemblBacteriaiAAN00654; AAN00654; SAG1791.
GeneIDi1014600.
KEGGisag:SAG1791.
PATRICifig|208435.3.peg.1799.

Similar proteinsi

Entry informationi

Entry nameiDLTS_STRA5
AccessioniPrimary (citable) accession number: Q8DXQ8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 23, 2003
Last sequence update: March 1, 2003
Last modified: October 25, 2017
This is version 97 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome