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Q8DW17 (AGUA_STRMU) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 53. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Putative agmatine deiminase
EC=3.5.3.12
Alternative name(s):
Agmatine iminohydrolase
Gene names
Name:aguA
Ordered Locus Names:SMU_264
OrganismStreptococcus mutans [Complete proteome] [HAMAP]
Taxonomic identifier1309 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Lactobacillales › Streptococcaceae › Streptococcus

Protein attributes

Sequence length369 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

Agmatine + H2O = N-carbamoylputrescine + NH3. HAMAP MF_01841

Sequence similarities

Belongs to the agmatine deiminase family.

Ontologies

Keywords
   Molecular functionHydrolase
   Technical term3D-structure
Complete proteome
Gene Ontology (GO)
   Biological processputrescine biosynthetic process

Inferred from electronic annotation. Source: InterPro

   Molecular functionagmatine deiminase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 369369Putative agmatine deiminase HAMAP MF_01841
PRO_0000194344

Sites

Active site3611Amidino-cysteine intermediate By similarity

Secondary structure

1 ........................................................................ 369
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
Q8DW17 [UniParc].

Last modified March 1, 2003. Version 1.
Checksum: 568713173C4AA7D7

FASTA36941,837
        10         20         30         40         50         60 
MAKRIKNTTP KQDGFRMPGE FEKQKQIWML WPWRNDNWRL GAKPAQKAFL EVAEAISEFE 

        70         80         90        100        110        120 
PVSLCVPPLQ YENALARVSE LGSHNIRIIE MTNDDAWIRD CGPTFLVNDK GDLRAVDWEF 

       130        140        150        160        170        180 
NAWGGLVDGL YFPWDQDALV ARKVCEIEGV DSYKTKDFVL EGGSIHVDGE GTVLVTEMCL 

       190        200        210        220        230        240 
LHPSRNPHLT KEDIEDKLKD YLNCVKVLWV KDGIDPYETN GHIDDVACFI RPGEVACIYT 

       250        260        270        280        290        300 
DDKEHPFYQE AKAAYDFLSQ QTDAKGRPLK VHKMCVTKEP CYLQEAATID YVEGSIPREE 

       310        320        330        340        350        360 
GEMAIASYLN FLIVNGGIIL PQYGDENDQL AKQQVQEMFP DRKVVGVRTE EIAYGGGNIH 


CITQQQPAT

« Hide

References

« Hide 'large scale' references
[1]"Genome sequence of Streptococcus mutans UA159, a cariogenic dental pathogen."
Ajdic D.J., McShan W.M., McLaughlin R.E., Savic G., Chang J., Carson M.B., Primeaux C., Tian R., Kenton S., Jia H.G., Lin S.P., Qian Y., Li S., Zhu H., Najar F.Z., Lai H., White J., Roe B.A., Ferretti J.J.
Proc. Natl. Acad. Sci. U.S.A. 99:14434-14439(2002) [PubMed: 12397186] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 700610 / UA159 / Serotype c.
[2]"Analysis of an agmatine deiminase gene cluster in Streptococcus mutans UA159."
Griswold A.R., Chen Y.-Y.M., Burne R.A.
J. Bacteriol. 186:1902-1904(2004) [PubMed: 14996823] [Abstract]
Cited for: IDENTIFICATION.
Strain: ATCC 700610 / UA159 / Serotype c.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE014133 Genomic DNA. Translation: AAN58033.1.
BK004003 Genomic DNA. Translation: DAA04558.1.
RefSeqNP_720727.1. NC_004350.2.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
2EWOX-ray2.90A/B/C/D/E/F/G/H/I/J/K/L1-369[»]
ProteinModelPortalQ8DW17.
SMRQ8DW17. Positions 2-369.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBSTRT00000014145; EBSTRP00000013627; EBSTRG00000014145.
GeneID1027853.
GenomeReviewsGene locus SMU_264 in contig AE014133_GR.
KEGGsmu:SMU_264.
NMPDRfig|210007.1.peg.240.
PATRIC19662789. VBIStrMut61772_0230.

Organism-specific databases

CMRSearch...

Phylogenomic databases

GeneTreeEBGT00050000029528.
HOGENOMHBG668771.
OMAFLIVNGG.
ProtClustDBPRK13551.

Enzyme and pathway databases

BioCycSMUT210007:SMU_264-MONOMER.

Family and domain databases

HAMAPMF_01841. Agmatine_deimin.
[Tree]
InterProIPR017754. Agmatine_deiminase.
IPR007466. Peptidyl-Arg-deiminase_porph.
[Graphical view]
KOK10536.
PfamPF04371. PAD_porph. 1 hit.
[Graphical view]
TIGRFAMsTIGR03380. Agmatine_aguA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameAGUA_STRMU
AccessionPrimary (citable) accession number: Q8DW17
Secondary accession number(s): Q6IFZ0
Entry history
Integrated into UniProtKB/Swiss-Prot: August 16, 2005
Last sequence update: March 1, 2003
Last modified: January 25, 2012
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families

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