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Q8DVF4

- TRPF_STRMU

UniProt

Q8DVF4 - TRPF_STRMU

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Protein
N-(5'-phosphoribosyl)anthranilate isomerase
Gene
trpF, SMU_536
Organism
Streptococcus mutans serotype c (strain ATCC 700610 / UA159)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. phosphoribosylanthranilate isomerase activity Source: UniProtKB-EC

GO - Biological processi

  1. tryptophan biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Amino-acid biosynthesis, Aromatic amino acid biosynthesis, Tryptophan biosynthesis

Enzyme and pathway databases

BioCyciSMUT210007:GC7Z-529-MONOMER.
UniPathwayiUPA00035; UER00042.

Names & Taxonomyi

Protein namesi
Recommended name:
N-(5'-phosphoribosyl)anthranilate isomerase (EC:5.3.1.24)
Short name:
PRAI
Gene namesi
Name:trpF
Ordered Locus Names:SMU_536
OrganismiStreptococcus mutans serotype c (strain ATCC 700610 / UA159)
Taxonomic identifieri210007 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
ProteomesiUP000002512: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 193193N-(5'-phosphoribosyl)anthranilate isomeraseUniRule annotation
PRO_0000154385Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi210007.SMU.536.

Structurei

3D structure databases

ProteinModelPortaliQ8DVF4.

Family & Domainsi

Sequence similaritiesi

Belongs to the TrpF family.

Phylogenomic databases

eggNOGiCOG0135.
KOiK01817.
OMAiTHDWEIS.
OrthoDBiEOG6N94DF.
PhylomeDBiQ8DVF4.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00135. PRAI.
InterProiIPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamiPF00697. PRAI. 1 hit.
[Graphical view]
SUPFAMiSSF51366. SSF51366. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8DVF4-1 [UniParc]FASTAAdd to Basket

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MTKVKICGLS TQEAVTAAVS SGADYIGFVF AKSKRQVSLE QAQKLAKMIP    50
EKVKKVGVFV SPTLEELKIA IKTVPLDLVQ VHGDYDEDLQ TDFSVPLIRA 100
VQIKKGKENL TSKADYLLFD APIAGSGETF DWQQLETEQL QKPFFIAGGL 150
TSDNVKECIE HFAPYAVDVS SGVETNGRKD IEKIKRFIES VKK 193
Length:193
Mass (Da):21,313
Last modified:March 1, 2003 - v1
Checksum:i8FC3FA0A77282B64
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE014133 Genomic DNA. Translation: AAN58279.1.
RefSeqiNP_720973.1. NC_004350.2.

Genome annotation databases

EnsemblBacteriaiAAN58279; AAN58279; SMU_536.
GeneIDi1028012.
KEGGismu:SMU_536.
PATRICi19663281. VBIStrMut61772_0473.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE014133 Genomic DNA. Translation: AAN58279.1 .
RefSeqi NP_720973.1. NC_004350.2.

3D structure databases

ProteinModelPortali Q8DVF4.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 210007.SMU.536.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAN58279 ; AAN58279 ; SMU_536 .
GeneIDi 1028012.
KEGGi smu:SMU_536.
PATRICi 19663281. VBIStrMut61772_0473.

Phylogenomic databases

eggNOGi COG0135.
KOi K01817.
OMAi THDWEIS.
OrthoDBi EOG6N94DF.
PhylomeDBi Q8DVF4.

Enzyme and pathway databases

UniPathwayi UPA00035 ; UER00042 .
BioCyci SMUT210007:GC7Z-529-MONOMER.

Family and domain databases

Gene3Di 3.20.20.70. 1 hit.
HAMAPi MF_00135. PRAI.
InterProi IPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view ]
Pfami PF00697. PRAI. 1 hit.
[Graphical view ]
SUPFAMi SSF51366. SSF51366. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700610 / UA159.

Entry informationi

Entry nameiTRPF_STRMU
AccessioniPrimary (citable) accession number: Q8DVF4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 25, 2003
Last sequence update: March 1, 2003
Last modified: July 9, 2014
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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