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Q8DVF4

- TRPF_STRMU

UniProt

Q8DVF4 - TRPF_STRMU

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Protein

N-(5'-phosphoribosyl)anthranilate isomerase

Gene

trpF

Organism
Streptococcus mutans serotype c (strain ATCC 700610 / UA159)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. phosphoribosylanthranilate isomerase activity Source: UniProtKB-EC

GO - Biological processi

  1. tryptophan biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Amino-acid biosynthesis, Aromatic amino acid biosynthesis, Tryptophan biosynthesis

Enzyme and pathway databases

BioCyciSMUT210007:GC7Z-529-MONOMER.
UniPathwayiUPA00035; UER00042.

Names & Taxonomyi

Protein namesi
Recommended name:
N-(5'-phosphoribosyl)anthranilate isomeraseUniRule annotation (EC:5.3.1.24UniRule annotation)
Short name:
PRAIUniRule annotation
Gene namesi
Name:trpFUniRule annotation
Ordered Locus Names:SMU_536
OrganismiStreptococcus mutans serotype c (strain ATCC 700610 / UA159)
Taxonomic identifieri210007 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
ProteomesiUP000002512: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 193193N-(5'-phosphoribosyl)anthranilate isomerasePRO_0000154385Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi210007.SMU.536.

Structurei

3D structure databases

ProteinModelPortaliQ8DVF4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the TrpF family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0135.
KOiK01817.
OMAiTHDWEIS.
OrthoDBiEOG6N94DF.
PhylomeDBiQ8DVF4.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00135. PRAI.
InterProiIPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamiPF00697. PRAI. 1 hit.
[Graphical view]
SUPFAMiSSF51366. SSF51366. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8DVF4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTKVKICGLS TQEAVTAAVS SGADYIGFVF AKSKRQVSLE QAQKLAKMIP
60 70 80 90 100
EKVKKVGVFV SPTLEELKIA IKTVPLDLVQ VHGDYDEDLQ TDFSVPLIRA
110 120 130 140 150
VQIKKGKENL TSKADYLLFD APIAGSGETF DWQQLETEQL QKPFFIAGGL
160 170 180 190
TSDNVKECIE HFAPYAVDVS SGVETNGRKD IEKIKRFIES VKK
Length:193
Mass (Da):21,313
Last modified:March 1, 2003 - v1
Checksum:i8FC3FA0A77282B64
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014133 Genomic DNA. Translation: AAN58279.1.
RefSeqiNP_720973.1. NC_004350.2.

Genome annotation databases

EnsemblBacteriaiAAN58279; AAN58279; SMU_536.
GeneIDi1028012.
KEGGismu:SMU_536.
PATRICi19663281. VBIStrMut61772_0473.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014133 Genomic DNA. Translation: AAN58279.1 .
RefSeqi NP_720973.1. NC_004350.2.

3D structure databases

ProteinModelPortali Q8DVF4.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 210007.SMU.536.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAN58279 ; AAN58279 ; SMU_536 .
GeneIDi 1028012.
KEGGi smu:SMU_536.
PATRICi 19663281. VBIStrMut61772_0473.

Phylogenomic databases

eggNOGi COG0135.
KOi K01817.
OMAi THDWEIS.
OrthoDBi EOG6N94DF.
PhylomeDBi Q8DVF4.

Enzyme and pathway databases

UniPathwayi UPA00035 ; UER00042 .
BioCyci SMUT210007:GC7Z-529-MONOMER.

Family and domain databases

Gene3Di 3.20.20.70. 1 hit.
HAMAPi MF_00135. PRAI.
InterProi IPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view ]
Pfami PF00697. PRAI. 1 hit.
[Graphical view ]
SUPFAMi SSF51366. SSF51366. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700610 / UA159.

Entry informationi

Entry nameiTRPF_STRMU
AccessioniPrimary (citable) accession number: Q8DVF4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 25, 2003
Last sequence update: March 1, 2003
Last modified: October 1, 2014
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3