Putative uncharacterized protein - Streptococcus mutans

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Q8DUW5 (Q8DUW5_STRMU) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 50. History...

Clusters with 100%, 90%, 50% identity |

Third-party data

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Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info Customize order

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Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info Customize order

Names and origin

Protein names

Submitted name:
Putative uncharacterized protein EMBL AAN58496.1

Gene names

Ordered Locus Names:

SMU_776

Organism

Streptococcus mutans [Complete proteome] [HAMAP]

Taxonomic identifier

Taxonomic lineage

Bacteria › Firmicutes › Lactobacillales › Streptococcaceae › Streptococcus

Protein attributes

Sequence length	385 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Subcellular location

Cytoplasm By similarity SAAS SAAS019614.

Ontologies

Keywords
Biological process	rRNA processing SAAS SAAS019614
Cellular component	Cytoplasm SAAS SAAS019614
Ligand	S-adenosyl-L-methionine SAAS SAAS019614
Molecular function	Methyltransferase SAAS SAAS019614 Transferase
Technical term	3D-structure PDB 2B78 PDB 3LDF Complete proteome
Gene Ontology (GO)
Molecular function	methyltransferase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Regions

Region

5

S-adenosyl-L-homocysteine binding PDB 3LDF

Sites

Binding site

1

S-adenosyl-L-homocysteine; via carbonyl oxygen PDB 3LDF

Binding site

1

S-adenosyl-L-homocysteine; via amide nitrogen PDB 3LDF

Binding site

1

S-adenosyl-L-homocysteine PDB 3LDF

Sequences

Sequence

Length

Mass (Da)

Tools

Q8DUW5 [UniParc].

Last modified March 1, 2003. Version 1.
Checksum: D025EF430B79A23B
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385

43,682

        10         20         30         40         50         60 
MIKLMVGSFA EKKLKRGVQL LSSRDYPNLN LDNQVVQLYS DADIFLGTAY LSKQNKGVGW 

        70         80         90        100        110        120 
LISPKKVSLN VTYFIKLFQW SKDKRKNFAH SKLTTAYRLF NQDGDSFGGV TIDCYGDFVL 

       130        140        150        160        170        180 
FSWYNSFVYQ IRDEIVAAFR QVYPNFLGAY EKIRFKGIDN VSAHLYGQEA PEQFLILENG 

       190        200        210        220        230        240 
ISYNVFLNDG LMTGIFLDQR QVRNELINGS AAGKTVLNLF SYTAAFSVAA AMGGAMATTS 

       250        260        270        280        290        300 
VDLAKRSRAL SLAHFEANHL DMANHQLVVM DVFDYFKYAR RHHLTYDIII IDPPSFARNK 

       310        320        330        340        350        360 
KEVFSVSKDY HKLIRQGLEI LSENGLIIAS TNAANMTVSQ FKKQIEKGFG KQKHTYLDLQ 

       370        380 
QLPSDFAVNV QDESSNYLKV FTIKV

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Genome sequence of Streptococcus mutans UA159, a cariogenic dental pathogen." Ajdic D.J., McShan W.M., McLaughlin R.E., Savic G., Chang J., Carson M.B., Primeaux C., Tian R., Kenton S., Jia H.G., Lin S.P., Qian Y., Li S., Zhu H., Najar F.Z., Lai H., White J., Roe B.A., Ferretti J.J. Proc. Natl. Acad. Sci. U.S.A. 99:14434-14439(2002) [PubMed: 12397186] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 700610 / UA159 / Serotype c.
[2]	"A putative sam-dependent methyltransferase from Streptococcus mutans." Nan J., Wang K.T., Su X.D. Submitted (OCT-2005) to the PDB data bank Cited for: X-RAY CRYSTALLOGRAPHY (2.00 ANGSTROMS).
[3]	"Crystal structure of SMU.776 complexed with SAH." Wang K.-T., Nan J., Su X.-D. Submitted (JAN-2010) to the PDB data bank Cited for: X-RAY CRYSTALLOGRAPHY (2.23 ANGSTROMS) IN COMPLEX WITH S-ADENOSYL-L-HOMOCYSTEINE.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AE014133 Genomic DNA. Translation: AAN58496.1.

RefSeq

NP_721190.1. NC_004350.2.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
2B78	X-ray	2.00	A	1-385	[»]
3LDF	X-ray	2.23	A	1-385	[»]

ProteinModelPortal

SMR

Q8DUW5. Positions 1-385.

ModBase

Protocols and materials databases

StructuralBiologyKnowledgebase

Genome annotation databases

EnsemblBacteria

EBSTRT00000014034; EBSTRP00000013516; EBSTRG00000014034.

GeneID

GenomeReviews

Gene locus SMU_776 in contig AE014133_GR.

KEGG

NMPDR

fig|210007.1.peg.703.

PATRIC

19663709. VBIStrMut61772_0687.

Organism-specific databases

CMR

Phylogenomic databases

GeneTree

EBGT00050000027121.

HOGENOM

OMA

ProtClustDB

Enzyme and pathway databases

BioCyc

SMUT210007:SMU_776-MONOMER.

Family and domain databases

InterPro

IPR015947. PUA-like_domain.
IPR019614. SAM-dep_methyl-trfase.
[Graphical view]

KO

Pfam

PF10672. Methyltrans_SAM. 1 hit.
[Graphical view]

SUPFAM

SSF88697. PUA-like. 1 hit.

ProtoNet

Entry information

Entry name

Q8DUW5_STRMU

Accession

Primary (citable) accession number: Q8DUW5

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2003
Last sequence update:	March 1, 2003
Last modified:	January 25, 2012
This is version 50 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

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Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info