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Q8DQZ1

- LACG1_STRR6

UniProt

Q8DQZ1 - LACG1_STRR6

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Protein

6-phospho-beta-galactosidase 1

Gene
lacG1, spr0424
Organism
Streptococcus pneumoniae (strain ATCC BAA-255 / R6)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

A 6-phospho-beta-D-galactoside + H2O = 6-phospho-D-galactose + an alcohol.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei164 – 1641Proton donor By similarity
Active sitei378 – 3781Nucleophile By similarity

GO - Molecular functioni

  1. 6-phospho-beta-galactosidase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. lactose catabolic process via tagatose-6-phosphate Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Glycosidase, Hydrolase

Enzyme and pathway databases

BioCyciSPNE171101:GJC8-432-MONOMER.
UniPathwayiUPA00542; UER00605.

Protein family/group databases

CAZyiGH1. Glycoside Hydrolase Family 1.

Names & Taxonomyi

Protein namesi
Recommended name:
6-phospho-beta-galactosidase 1 (EC:3.2.1.85)
Alternative name(s):
Beta-D-phosphogalactoside galactohydrolase 1
Short name:
PGALase 1
P-beta-Gal 1
Short name:
PBG 1
Gene namesi
Name:lacG1
Ordered Locus Names:spr0424
OrganismiStreptococcus pneumoniae (strain ATCC BAA-255 / R6)
Taxonomic identifieri171101 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
ProteomesiUP000000586: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 4704706-phospho-beta-galactosidase 1UniRule annotationPRO_0000260732Add
BLAST

Proteomic databases

PRIDEiQ8DQZ1.

Interactioni

Protein-protein interaction databases

STRINGi171101.spr0424.

Structurei

3D structure databases

ProteinModelPortaliQ8DQZ1.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG2723.
HOGENOMiHOG000088632.
KOiK01220.
OMAiWDRYLHE.
OrthoDBiEOG60658J.

Family and domain databases

Gene3Di3.20.20.80. 1 hit.
HAMAPiMF_01574. LacG.
InterProiIPR005928. 6P-beta-galactosidase.
IPR001360. Glyco_hydro_1.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERiPTHR10353. PTHR10353. 1 hit.
PfamiPF00232. Glyco_hydro_1. 1 hit.
[Graphical view]
PRINTSiPR00131. GLHYDRLASE1.
SUPFAMiSSF51445. SSF51445. 1 hit.
TIGRFAMsiTIGR01233. lacG. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8DQZ1-1 [UniParc]FASTAAdd to Basket

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MENLQVKALP KEFLLGTATA AYQVEGATRV DGKGINMWDV YLQENSPFLP    50
DPASDFYYRY EEDIALAAEH GLQALRLSIS WVRIFPDIDG DANVLAVHYY 100
HRVFQSCLKH NVIPFVSLHH FDSPQKMLET GDWLNRENID RFIRYARFCF 150
QEFTEVKHWF TINELMSLAA GQYIGGQFPP NHHFQLSEAI QANHNMLLAH 200
ALAVLEFHQL GIEGKVGCIH ALKPGYPIDG QKENILAAKR YDVYNNKFLL 250
DGTFLGYYSE DTLFHLNQIL EANNSSFIIE DGDLEIMKRA APLNTMFVMN 300
YYRSEFIREY KGENRQEFNS TGIKGQSSFK LNALGEFVKK PGIPTTDWDW 350
NIYPQGLFDM LLRIKEEYPQ HPVIYLTENG TALKEVKPEG ENDIIDDSKR 400
IRYIEQHLHK VLEARDRGVN IQGYFIWSLQ DQFSWANGYN KRYGLFFVDY 450
ETQKRYIKKS ALWVKGLKRN 470
Length:470
Mass (Da):54,675
Last modified:March 1, 2003 - v1
Checksum:iCAE61D8921067D6D
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE007317 Genomic DNA. Translation: AAK99228.1.
PIRiH97924.
RefSeqiNP_358018.1. NC_003098.1.

Genome annotation databases

EnsemblBacteriaiAAK99228; AAK99228; spr0424.
GeneIDi934741.
KEGGispr:spr0424.
PATRICi19700689. VBIStrPne107296_0466.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE007317 Genomic DNA. Translation: AAK99228.1 .
PIRi H97924.
RefSeqi NP_358018.1. NC_003098.1.

3D structure databases

ProteinModelPortali Q8DQZ1.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 171101.spr0424.

Protein family/group databases

CAZyi GH1. Glycoside Hydrolase Family 1.

Proteomic databases

PRIDEi Q8DQZ1.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAK99228 ; AAK99228 ; spr0424 .
GeneIDi 934741.
KEGGi spr:spr0424.
PATRICi 19700689. VBIStrPne107296_0466.

Phylogenomic databases

eggNOGi COG2723.
HOGENOMi HOG000088632.
KOi K01220.
OMAi WDRYLHE.
OrthoDBi EOG60658J.

Enzyme and pathway databases

UniPathwayi UPA00542 ; UER00605 .
BioCyci SPNE171101:GJC8-432-MONOMER.

Family and domain databases

Gene3Di 3.20.20.80. 1 hit.
HAMAPi MF_01574. LacG.
InterProi IPR005928. 6P-beta-galactosidase.
IPR001360. Glyco_hydro_1.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view ]
PANTHERi PTHR10353. PTHR10353. 1 hit.
Pfami PF00232. Glyco_hydro_1. 1 hit.
[Graphical view ]
PRINTSi PR00131. GLHYDRLASE1.
SUPFAMi SSF51445. SSF51445. 1 hit.
TIGRFAMsi TIGR01233. lacG. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-255 / R6.

Entry informationi

Entry nameiLACG1_STRR6
AccessioniPrimary (citable) accession number: Q8DQZ1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 28, 2006
Last sequence update: March 1, 2003
Last modified: May 14, 2014
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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