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Q8DQZ1

- LACG1_STRR6

UniProt

Q8DQZ1 - LACG1_STRR6

Protein

6-phospho-beta-galactosidase 1

Gene

lacG1

Organism
Streptococcus pneumoniae (strain ATCC BAA-255 / R6)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 77 (01 Oct 2014)
      Sequence version 1 (01 Mar 2003)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    A 6-phospho-beta-D-galactoside + H2O = 6-phospho-D-galactose + an alcohol.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei164 – 1641Proton donorUniRule annotation
    Active sitei378 – 3781NucleophileUniRule annotation

    GO - Molecular functioni

    1. 6-phospho-beta-galactosidase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. lactose catabolic process via tagatose-6-phosphate Source: InterPro

    Keywords - Molecular functioni

    Glycosidase, Hydrolase

    Enzyme and pathway databases

    BioCyciSPNE171101:GJC8-432-MONOMER.
    UniPathwayiUPA00542; UER00605.

    Protein family/group databases

    CAZyiGH1. Glycoside Hydrolase Family 1.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    6-phospho-beta-galactosidase 1UniRule annotation (EC:3.2.1.85UniRule annotation)
    Alternative name(s):
    Beta-D-phosphogalactoside galactohydrolase 1UniRule annotation
    Short name:
    PGALase 1UniRule annotation
    P-beta-Gal 1UniRule annotation
    Short name:
    PBG 1UniRule annotation
    Gene namesi
    Name:lacG1UniRule annotation
    Ordered Locus Names:spr0424
    OrganismiStreptococcus pneumoniae (strain ATCC BAA-255 / R6)
    Taxonomic identifieri171101 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
    ProteomesiUP000000586: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 4704706-phospho-beta-galactosidase 1PRO_0000260732Add
    BLAST

    Proteomic databases

    PRIDEiQ8DQZ1.

    Interactioni

    Protein-protein interaction databases

    STRINGi171101.spr0424.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8DQZ1.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the glycosyl hydrolase 1 family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG2723.
    HOGENOMiHOG000088632.
    KOiK01220.
    OMAiWDRYLHE.
    OrthoDBiEOG60658J.

    Family and domain databases

    Gene3Di3.20.20.80. 1 hit.
    HAMAPiMF_01574. LacG.
    InterProiIPR005928. 6P-beta-galactosidase.
    IPR001360. Glyco_hydro_1.
    IPR013781. Glyco_hydro_catalytic_dom.
    IPR017853. Glycoside_hydrolase_SF.
    [Graphical view]
    PANTHERiPTHR10353. PTHR10353. 1 hit.
    PfamiPF00232. Glyco_hydro_1. 1 hit.
    [Graphical view]
    PRINTSiPR00131. GLHYDRLASE1.
    SUPFAMiSSF51445. SSF51445. 1 hit.
    TIGRFAMsiTIGR01233. lacG. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q8DQZ1-1 [UniParc]FASTAAdd to Basket

    « Hide

    MENLQVKALP KEFLLGTATA AYQVEGATRV DGKGINMWDV YLQENSPFLP    50
    DPASDFYYRY EEDIALAAEH GLQALRLSIS WVRIFPDIDG DANVLAVHYY 100
    HRVFQSCLKH NVIPFVSLHH FDSPQKMLET GDWLNRENID RFIRYARFCF 150
    QEFTEVKHWF TINELMSLAA GQYIGGQFPP NHHFQLSEAI QANHNMLLAH 200
    ALAVLEFHQL GIEGKVGCIH ALKPGYPIDG QKENILAAKR YDVYNNKFLL 250
    DGTFLGYYSE DTLFHLNQIL EANNSSFIIE DGDLEIMKRA APLNTMFVMN 300
    YYRSEFIREY KGENRQEFNS TGIKGQSSFK LNALGEFVKK PGIPTTDWDW 350
    NIYPQGLFDM LLRIKEEYPQ HPVIYLTENG TALKEVKPEG ENDIIDDSKR 400
    IRYIEQHLHK VLEARDRGVN IQGYFIWSLQ DQFSWANGYN KRYGLFFVDY 450
    ETQKRYIKKS ALWVKGLKRN 470
    Length:470
    Mass (Da):54,675
    Last modified:March 1, 2003 - v1
    Checksum:iCAE61D8921067D6D
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE007317 Genomic DNA. Translation: AAK99228.1.
    PIRiH97924.
    RefSeqiNP_358018.1. NC_003098.1.

    Genome annotation databases

    EnsemblBacteriaiAAK99228; AAK99228; spr0424.
    GeneIDi934741.
    KEGGispr:spr0424.
    PATRICi19700689. VBIStrPne107296_0466.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE007317 Genomic DNA. Translation: AAK99228.1 .
    PIRi H97924.
    RefSeqi NP_358018.1. NC_003098.1.

    3D structure databases

    ProteinModelPortali Q8DQZ1.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 171101.spr0424.

    Protein family/group databases

    CAZyi GH1. Glycoside Hydrolase Family 1.

    Proteomic databases

    PRIDEi Q8DQZ1.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAK99228 ; AAK99228 ; spr0424 .
    GeneIDi 934741.
    KEGGi spr:spr0424.
    PATRICi 19700689. VBIStrPne107296_0466.

    Phylogenomic databases

    eggNOGi COG2723.
    HOGENOMi HOG000088632.
    KOi K01220.
    OMAi WDRYLHE.
    OrthoDBi EOG60658J.

    Enzyme and pathway databases

    UniPathwayi UPA00542 ; UER00605 .
    BioCyci SPNE171101:GJC8-432-MONOMER.

    Family and domain databases

    Gene3Di 3.20.20.80. 1 hit.
    HAMAPi MF_01574. LacG.
    InterProi IPR005928. 6P-beta-galactosidase.
    IPR001360. Glyco_hydro_1.
    IPR013781. Glyco_hydro_catalytic_dom.
    IPR017853. Glycoside_hydrolase_SF.
    [Graphical view ]
    PANTHERi PTHR10353. PTHR10353. 1 hit.
    Pfami PF00232. Glyco_hydro_1. 1 hit.
    [Graphical view ]
    PRINTSi PR00131. GLHYDRLASE1.
    SUPFAMi SSF51445. SSF51445. 1 hit.
    TIGRFAMsi TIGR01233. lacG. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC BAA-255 / R6.

    Entry informationi

    Entry nameiLACG1_STRR6
    AccessioniPrimary (citable) accession number: Q8DQZ1
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 28, 2006
    Last sequence update: March 1, 2003
    Last modified: October 1, 2014
    This is version 77 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Glycosyl hydrolases
      Classification of glycosyl hydrolase families and list of entries
    2. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3