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Protein
Submitted name:

Teichoic acid phosphorylcholine esterase/choline binding protein E (CbpE)

Gene

lytD

Organism
Streptococcus pneumoniae (strain ATCC BAA-255 / R6)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi61Calcium 1Combined sources1
Metal bindingi62Calcium 1Combined sources1
Metal bindingi62Calcium 2Combined sources1
Metal bindingi64Calcium 1; via carbonyl oxygenCombined sources1
Metal bindingi110Iron 1; via tele nitrogenCombined sources1
Metal bindingi110Zinc 1; via tele nitrogenCombined sources1
Metal bindingi112Iron 1; via pros nitrogenCombined sources1
Metal bindingi112Zinc 1; via pros nitrogenCombined sources1
Metal bindingi114Iron 2Combined sources1
Metal bindingi114Zinc 2Combined sources1
Metal bindingi115Iron 2; via tele nitrogenCombined sources1
Metal bindingi115Zinc 2; via tele nitrogenCombined sources1
Metal bindingi117Calcium 2; via carbonyl oxygenCombined sources1
Metal bindingi120Calcium 2Combined sources1
Metal bindingi121Calcium 2Combined sources1
Metal bindingi208Iron 1Combined sources1
Metal bindingi208Zinc 1Combined sources1
Metal bindingi228Iron 1Combined sources1
Metal bindingi228Iron 2Combined sources1
Metal bindingi228Zinc 1Combined sources1
Metal bindingi228Zinc 2Combined sources1
Metal bindingi254Iron 2; via tele nitrogenCombined sources1
Metal bindingi254Zinc 2; via tele nitrogenCombined sources1

GO - Molecular functioni

Complete GO annotation...

Keywords - Ligandi

CalciumCombined sources, IronCombined sources, Metal-bindingCombined sources, ZincCombined sources

Names & Taxonomyi

Protein namesi
Submitted name:
Teichoic acid phosphorylcholine esterase/choline binding protein E (CbpE)Imported
Gene namesi
Name:lytDImported
Ordered Locus Names:spr0831Imported
OrganismiStreptococcus pneumoniae (strain ATCC BAA-255 / R6)Imported
Taxonomic identifieri171101 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
Proteomesi
  • UP000000586 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 25Sequence analysisAdd BLAST25
ChainiPRO_500430444926 – 627Sequence analysisAdd BLAST602

Interactioni

Protein-protein interaction databases

STRINGi171101.spr0831.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1WRAX-ray2.00A/B27-334[»]
2BIBX-ray1.92A26-572[»]
ProteinModelPortaliQ8DQ62.
SMRiQ8DQ62.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ8DQ62.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini42 – 278Lactamase_BInterPro annotationAdd BLAST237

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG4108AUE. Bacteria.
COG2333. LUCA.
HOGENOMiHOG000285074.
OMAiWYFYKTG.

Family and domain databases

Gene3Di3.60.15.10. 1 hit.
InterProiIPR018337. Cell_wall/Cho-bd_repeat.
IPR001279. Metallo-B-lactamas.
[Graphical view]
PfamiPF01473. CW_binding_1. 7 hits.
PF00753. Lactamase_B. 1 hit.
[Graphical view]
SMARTiSM00849. Lactamase_B. 1 hit.
[Graphical view]
SUPFAMiSSF56281. SSF56281. 1 hit.
PROSITEiPS51170. CW. 10 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8DQ62-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKKKLTSLAL VGAFLGLSWY GNVQAQESSG NKIHFINVQE GGSDAIILES
60 70 80 90 100
NGHFAMVDTG EDYDFPDGSD SRYPWREGIE TSYKHVLTDR VFRRLKELSV
110 120 130 140 150
QKLDFILVTH THSDHIGNVD ELLSTYPVDR VYLKKYSDSR ITNSERLWDN
160 170 180 190 200
LYGYDKVLQT ATETGVSVIQ NITQGDAHFQ FGDMDIQLYN YENETDSSGE
210 220 230 240 250
LKKIWDDNSN SLISVVKVNG KKIYLGGDLD NVHGAEDKYG PLIGKVDLMK
260 270 280 290 300
FNHHHDTNKS NTKDFIKNLS PSLIVQTSDS LPWKNGVDSE YVNWLKERGI
310 320 330 340 350
ERINAASKDY DATVFDIRKD GFVNISTSYK PIPSFQAGWH KSAYGNWWYQ
360 370 380 390 400
APDSTGEYAV GWNEIEGEWY YFNQTGILLQ NQWKKWNNHW FYLTDSGASA
410 420 430 440 450
KNWKKIDGIW YYFNKENQME IGWVQDKEQW YYLDVDGSMK TGWLQYMGQW
460 470 480 490 500
YYFAPSGEMK MGWVKDKETW YYMDSTGVMK TGEIEVAGQH YYLEDSGAMK
510 520 530 540 550
QGWHKKANDW YFYKTDGSRA VGWIKDKDKW YFLKENGQLL VNGKTPEGYT
560 570 580 590 600
VDSSGAWLVD VSIEKSATIK TTSHSEIKES KEVVKKDLEN KETSQHESVT
610 620
NFSTSQDLTS STSQSSETSV NKSESEQ
Length:627
Mass (Da):72,118
Last modified:March 1, 2003 - v1
Checksum:i6B309D30177369F5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE007317 Genomic DNA. Translation: AAK99635.1.
PIRiG97975.
RefSeqiNP_358425.1. NC_003098.1.
WP_000728289.1. NC_003098.1.

Genome annotation databases

EnsemblBacteriaiAAK99635; AAK99635; spr0831.
GeneIDi934372.
KEGGispr:spr0831.
PATRICi19701602. VBIStrPne107296_0920.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE007317 Genomic DNA. Translation: AAK99635.1.
PIRiG97975.
RefSeqiNP_358425.1. NC_003098.1.
WP_000728289.1. NC_003098.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1WRAX-ray2.00A/B27-334[»]
2BIBX-ray1.92A26-572[»]
ProteinModelPortaliQ8DQ62.
SMRiQ8DQ62.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi171101.spr0831.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAK99635; AAK99635; spr0831.
GeneIDi934372.
KEGGispr:spr0831.
PATRICi19701602. VBIStrPne107296_0920.

Phylogenomic databases

eggNOGiENOG4108AUE. Bacteria.
COG2333. LUCA.
HOGENOMiHOG000285074.
OMAiWYFYKTG.

Miscellaneous databases

EvolutionaryTraceiQ8DQ62.

Family and domain databases

Gene3Di3.60.15.10. 1 hit.
InterProiIPR018337. Cell_wall/Cho-bd_repeat.
IPR001279. Metallo-B-lactamas.
[Graphical view]
PfamiPF01473. CW_binding_1. 7 hits.
PF00753. Lactamase_B. 1 hit.
[Graphical view]
SMARTiSM00849. Lactamase_B. 1 hit.
[Graphical view]
SUPFAMiSSF56281. SSF56281. 1 hit.
PROSITEiPS51170. CW. 10 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ8DQ62_STRR6
AccessioniPrimary (citable) accession number: Q8DQ62
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: November 2, 2016
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.