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Protein

1,4-alpha-glucan branching enzyme GlgB

Gene

glgB

Organism
Streptococcus pneumoniae (strain ATCC BAA-255 / R6)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.UniRule annotation

Catalytic activityi

Transfers a segment of a (1->4)-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain.UniRule annotation

Pathwayi: glycogen biosynthesis

This protein is involved in the pathway glycogen biosynthesis, which is part of Glycan biosynthesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway glycogen biosynthesis and in Glycan biosynthesis.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei304NucleophileUniRule annotation1
Active sitei355Proton donorUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosyltransferase, Transferase
Biological processCarbohydrate metabolism, Glycogen biosynthesis, Glycogen metabolism

Enzyme and pathway databases

BioCyciSPNE171101:SPR1029-MONOMER
UniPathwayiUPA00164

Protein family/group databases

CAZyiCBM48 Carbohydrate-Binding Module Family 48
GH13 Glycoside Hydrolase Family 13

Names & Taxonomyi

Protein namesi
Recommended name:
1,4-alpha-glucan branching enzyme GlgBUniRule annotation (EC:2.4.1.18UniRule annotation)
Alternative name(s):
1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferaseUniRule annotation
Alpha-(1->4)-glucan branching enzymeUniRule annotation
Glycogen branching enzymeUniRule annotation
Short name:
BEUniRule annotation
Gene namesi
Name:glgBUniRule annotation
Ordered Locus Names:spr1029
OrganismiStreptococcus pneumoniae (strain ATCC BAA-255 / R6)
Taxonomic identifieri171101 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
Proteomesi
  • UP000000586 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001887531 – 6421,4-alpha-glucan branching enzyme GlgBAdd BLAST642

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi171101.spr1029

Structurei

3D structure databases

ProteinModelPortaliQ8DPS6
SMRiQ8DPS6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C9C Bacteria
COG0296 LUCA
HOGENOMiHOG000283037
KOiK00700
OMAiEVVHGKS

Family and domain databases

Gene3Di2.60.40.10, 1 hit
2.60.40.1180, 1 hit
HAMAPiMF_00685 GlgB, 1 hit
InterProiView protein in InterPro
IPR006048 A-amylase/branching_C
IPR037439 Branching_enzy
IPR006407 GlgB
IPR006047 Glyco_hydro_13_cat_dom
IPR004193 Glyco_hydro_13_N
IPR013780 Glyco_hydro_b
IPR017853 Glycoside_hydrolase_SF
IPR013783 Ig-like_fold
IPR014756 Ig_E-set
PANTHERiPTHR43651 PTHR43651, 1 hit
PfamiView protein in Pfam
PF00128 Alpha-amylase, 1 hit
PF02806 Alpha-amylase_C, 1 hit
PF02922 CBM_48, 1 hit
PIRSFiPIRSF000463 GlgB, 1 hit
SMARTiView protein in SMART
SM00642 Aamy, 1 hit
SUPFAMiSSF51445 SSF51445, 1 hit
SSF81296 SSF81296, 1 hit
TIGRFAMsiTIGR01515 branching_enzym, 1 hit

Sequencei

Sequence statusi: Complete.

Q8DPS6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDNREALKTF MTGENFYLQH YLGAHREELN GEHGYTFRVW APNAQAVHLV
60 70 80 90 100
GDFTNWIENQ IPMVRNDFGV WEVFTNMAQE GHIYKYHVTR QNGHQLMKID
110 120 130 140 150
PFAVRYEARP GTGAIVTELP EKKWKDGLWL ARRKRWGFAE RPVNIYEVHA
160 170 180 190 200
GSWKRNPDGS PYSFAQLKDE LIPYLVEMNY THIEFMPLMS HPLGLSWGYQ
210 220 230 240 250
LMGYFALEHA YGRPEEFQDF VEECHTHNIG VIVDWVPGHF TINDDALAYY
260 270 280 290 300
DGTPTFEYQD HNKAHNHGWG ALNFDLGKNE VQSFLISCIK HWIDVYHLDG
310 320 330 340 350
IRVDAVSNML YLDYDDAPWT PNKDGGNLNY EGYYFLQRLN EVIKLEYPDV
360 370 380 390 400
MMIAEESSSA TKITGMKEIG GLGFDYKWNM GWMNDILRFY EEDPIYRKYD
410 420 430 440 450
FNLVTFSFMY VFKENYLLPF SHDEVVHGKK SMMHKMWGDR YNQFAGLRNL
460 470 480 490 500
YTYQICHPGK KLLFMGSEYG QFLEWKSEEQ LEWSNLEDPM NAKMKYFTSQ
510 520 530 540 550
LNQFYKDHRC LWEIDTSYDG IEIIDADNRD QSVLSFIRKG KKGEMLVCIF
560 570 580 590 600
NMVPVERKDF TIGLPVAGIY EEVWNTELEE WGGVWKEHNQ TVQTQEGLWK
610 620 630 640
DYEQTLTFTL PAMGASVWKI KRRLKSTKTV TNKNPKGVEN EK
Length:642
Mass (Da):75,542
Last modified:March 1, 2003 - v1
Checksum:i1806CF2A59D7AEC0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE007317 Genomic DNA Translation: AAK99833.1
PIRiE98000
RefSeqiNP_358623.1, NC_003098.1
WP_000370258.1, NC_003098.1

Genome annotation databases

EnsemblBacteriaiAAK99833; AAK99833; spr1029
GeneIDi933336
KEGGispr:spr1029
PATRICifig|171101.6.peg.1117

Similar proteinsi

Entry informationi

Entry nameiGLGB_STRR6
AccessioniPrimary (citable) accession number: Q8DPS6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 15, 2003
Last sequence update: March 1, 2003
Last modified: June 20, 2018
This is version 100 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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