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Q8DPS6

- GLGB_STRR6

UniProt

Q8DPS6 - GLGB_STRR6

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Protein
1,4-alpha-glucan branching enzyme GlgB
Gene
glgB, spr1029
Organism
Streptococcus pneumoniae (strain ATCC BAA-255 / R6)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position By similarity.UniRule annotation

Catalytic activityi

Transfers a segment of a (1->4)-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei304 – 3041Nucleophile By similarity
Active sitei355 – 3551Proton donor By similarity

GO - Molecular functioni

  1. 1,4-alpha-glucan branching enzyme activity Source: UniProtKB-HAMAP
  2. cation binding Source: InterPro
  3. hydrolase activity, hydrolyzing O-glycosyl compounds Source: InterPro

GO - Biological processi

  1. glycogen biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Keywords - Biological processi

Carbohydrate metabolism, Glycogen biosynthesis, Glycogen metabolism

Enzyme and pathway databases

BioCyciSPNE171101:GJC8-1041-MONOMER.
UniPathwayiUPA00164.

Protein family/group databases

CAZyiCBM48. Carbohydrate-Binding Module Family 48.
GH13. Glycoside Hydrolase Family 13.

Names & Taxonomyi

Protein namesi
Recommended name:
1,4-alpha-glucan branching enzyme GlgB (EC:2.4.1.18)
Alternative name(s):
1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase
Alpha-(1->4)-glucan branching enzyme
Glycogen branching enzyme
Short name:
BE
Gene namesi
Name:glgB
Ordered Locus Names:spr1029
OrganismiStreptococcus pneumoniae (strain ATCC BAA-255 / R6)
Taxonomic identifieri171101 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
ProteomesiUP000000586: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 6426421,4-alpha-glucan branching enzyme GlgBUniRule annotation
PRO_0000188753Add
BLAST

Interactioni

Subunit structurei

Monomer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi171101.spr1029.

Structurei

3D structure databases

ProteinModelPortaliQ8DPS6.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0296.
HOGENOMiHOG000283037.
KOiK00700.
OMAiECHQNNI.
OrthoDBiEOG6JX7GT.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
HAMAPiMF_00685. GlgB.
InterProiIPR006048. A-amylase_b_C.
IPR006407. GlgB.
IPR015902. Glyco_hydro_13.
IPR013780. Glyco_hydro_13_b.
IPR006047. Glyco_hydro_13_cat_dom.
IPR004193. Glyco_hydro_13_N.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
[Graphical view]
PANTHERiPTHR10357. PTHR10357. 1 hit.
PfamiPF00128. Alpha-amylase. 1 hit.
PF02806. Alpha-amylase_C. 1 hit.
PF02922. CBM_48. 1 hit.
[Graphical view]
PIRSFiPIRSF000463. GlgB. 1 hit.
SUPFAMiSSF51445. SSF51445. 1 hit.
SSF81296. SSF81296. 1 hit.
TIGRFAMsiTIGR01515. branching_enzym. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8DPS6-1 [UniParc]FASTAAdd to Basket

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MDNREALKTF MTGENFYLQH YLGAHREELN GEHGYTFRVW APNAQAVHLV    50
GDFTNWIENQ IPMVRNDFGV WEVFTNMAQE GHIYKYHVTR QNGHQLMKID 100
PFAVRYEARP GTGAIVTELP EKKWKDGLWL ARRKRWGFAE RPVNIYEVHA 150
GSWKRNPDGS PYSFAQLKDE LIPYLVEMNY THIEFMPLMS HPLGLSWGYQ 200
LMGYFALEHA YGRPEEFQDF VEECHTHNIG VIVDWVPGHF TINDDALAYY 250
DGTPTFEYQD HNKAHNHGWG ALNFDLGKNE VQSFLISCIK HWIDVYHLDG 300
IRVDAVSNML YLDYDDAPWT PNKDGGNLNY EGYYFLQRLN EVIKLEYPDV 350
MMIAEESSSA TKITGMKEIG GLGFDYKWNM GWMNDILRFY EEDPIYRKYD 400
FNLVTFSFMY VFKENYLLPF SHDEVVHGKK SMMHKMWGDR YNQFAGLRNL 450
YTYQICHPGK KLLFMGSEYG QFLEWKSEEQ LEWSNLEDPM NAKMKYFTSQ 500
LNQFYKDHRC LWEIDTSYDG IEIIDADNRD QSVLSFIRKG KKGEMLVCIF 550
NMVPVERKDF TIGLPVAGIY EEVWNTELEE WGGVWKEHNQ TVQTQEGLWK 600
DYEQTLTFTL PAMGASVWKI KRRLKSTKTV TNKNPKGVEN EK 642
Length:642
Mass (Da):75,542
Last modified:March 1, 2003 - v1
Checksum:i1806CF2A59D7AEC0
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE007317 Genomic DNA. Translation: AAK99833.1.
PIRiE98000.
RefSeqiNP_358623.1. NC_003098.1.

Genome annotation databases

EnsemblBacteriaiAAK99833; AAK99833; spr1029.
GeneIDi933336.
KEGGispr:spr1029.
PATRICi19702000. VBIStrPne107296_1117.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE007317 Genomic DNA. Translation: AAK99833.1 .
PIRi E98000.
RefSeqi NP_358623.1. NC_003098.1.

3D structure databases

ProteinModelPortali Q8DPS6.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 171101.spr1029.

Protein family/group databases

CAZyi CBM48. Carbohydrate-Binding Module Family 48.
GH13. Glycoside Hydrolase Family 13.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAK99833 ; AAK99833 ; spr1029 .
GeneIDi 933336.
KEGGi spr:spr1029.
PATRICi 19702000. VBIStrPne107296_1117.

Phylogenomic databases

eggNOGi COG0296.
HOGENOMi HOG000283037.
KOi K00700.
OMAi ECHQNNI.
OrthoDBi EOG6JX7GT.

Enzyme and pathway databases

UniPathwayi UPA00164 .
BioCyci SPNE171101:GJC8-1041-MONOMER.

Family and domain databases

Gene3Di 2.60.40.10. 1 hit.
2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
HAMAPi MF_00685. GlgB.
InterProi IPR006048. A-amylase_b_C.
IPR006407. GlgB.
IPR015902. Glyco_hydro_13.
IPR013780. Glyco_hydro_13_b.
IPR006047. Glyco_hydro_13_cat_dom.
IPR004193. Glyco_hydro_13_N.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
[Graphical view ]
PANTHERi PTHR10357. PTHR10357. 1 hit.
Pfami PF00128. Alpha-amylase. 1 hit.
PF02806. Alpha-amylase_C. 1 hit.
PF02922. CBM_48. 1 hit.
[Graphical view ]
PIRSFi PIRSF000463. GlgB. 1 hit.
SUPFAMi SSF51445. SSF51445. 1 hit.
SSF81296. SSF81296. 1 hit.
TIGRFAMsi TIGR01515. branching_enzym. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-255 / R6.

Entry informationi

Entry nameiGLGB_STRR6
AccessioniPrimary (citable) accession number: Q8DPS6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 15, 2003
Last sequence update: March 1, 2003
Last modified: June 11, 2014
This is version 84 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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