ID   Q8DPM1_STRR6            Unreviewed;      1084 AA.
AC   Q8DPM1;
DT   01-MAR-2003, integrated into UniProtKB/TrEMBL.
DT   01-MAR-2003, sequence version 1.
DT   27-MAR-2024, entry version 109.
DE   SubName: Full=Uncharacterized restriction enzyme, interrupted-C {ECO:0000313|EMBL:AAK99904.1};
DE            EC=3.1.21.4 {ECO:0000313|EMBL:AAK99904.1};
GN   OrderedLocusNames=spr1101 {ECO:0000313|EMBL:AAK99904.1};
OS   Streptococcus pneumoniae (strain ATCC BAA-255 / R6).
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=171101 {ECO:0000313|EMBL:AAK99904.1, ECO:0000313|Proteomes:UP000000586};
RN   [1] {ECO:0000313|EMBL:AAK99904.1, ECO:0000313|Proteomes:UP000000586}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-255 / R6 {ECO:0000313|Proteomes:UP000000586};
RX   PubMed=11544234; DOI=10.1128/JB.183.19.5709-5717.2001;
RA   Hoskins J.A., Alborn W.Jr., Arnold J., Blaszczak L., Burgett S.,
RA   DeHoff B.S., Estrem S., Fritz L., Fu D.-J., Fuller W., Geringer C.,
RA   Gilmour R., Glass J.S., Khoja H., Kraft A., LaGace R., LeBlanc D.J.,
RA   Lee L.N., Lefkowitz E.J., Lu J., Matsushima P., McAhren S., McHenney M.,
RA   McLeaster K., Mundy C., Nicas T.I., Norris F.H., O'Gara M., Peery R.,
RA   Robertson G.T., Rockey P., Sun P.-M., Winkler M.E., Yang Y.,
RA   Young-Bellido M., Zhao G., Zook C., Baltz R.H., Jaskunas S.Richard.,
RA   Rosteck P.R.Jr., Skatrud P.L., Glass J.I.;
RT   "Genome of the bacterium Streptococcus pneumoniae strain R6.";
RL   J. Bacteriol. 183:5709-5717(2001).
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DR   EMBL; AE007317; AAK99904.1; -; Genomic_DNA.
DR   PIR; D98009; D98009.
DR   RefSeq; NP_358694.1; NC_003098.1.
DR   RefSeq; WP_001143843.1; NC_003098.1.
DR   AlphaFoldDB; Q8DPM1; -.
DR   STRING; 171101.spr1101; -.
DR   REBASE; 5624; SpnRII.
DR   KEGG; spr:spr1101; -.
DR   PATRIC; fig|171101.6.peg.1196; -.
DR   eggNOG; COG3206; Bacteria.
DR   eggNOG; COG4096; Bacteria.
DR   HOGENOM; CLU_005929_0_0_9; -.
DR   Proteomes; UP000000586; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0009036; F:type II site-specific deoxyribonuclease activity; IEA:UniProtKB-EC.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   InterPro; IPR006935; Helicase/UvrB_N.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR018306; Phage_T5_Orf172_DNA-bd.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   Pfam; PF04851; ResIII; 1.
DR   SMART; SM00974; T5orf172; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Hydrolase {ECO:0000313|EMBL:AAK99904.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000586}.
FT   DOMAIN          24..110
FT                   /note="Bacteriophage T5 Orf172 DNA-binding"
FT                   /evidence="ECO:0000259|SMART:SM00974"
FT   COILED          779..858
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   1084 AA;  125110 MW;  67AA475EDF4D5BB4 CRC64;
     MPVEIKTTKE IHPKIYAYTT PTVTSNEGWI KIGYTERDVT QRIKEQTHTA HIATDVLWTG
     DAAYTEEPDK GKTFKDHDFH HFLSFHDVER RPKTEWFYFN GTPEKSKNLF DKFVQHDLSG
     YQPGKGQDYT LRQEQEEAVA KTLAYFQEHA GGKFLWNAKP RFGKTLSTYD LARRMEAVNV
     LIVTNRPAIA NSWYDDFETF IAGQTTYKFV SESDSLKSRP ILSRQEFLGI LADDVRQLAF
     ISLQDLKGSV YLGGEHDKLK WVTDLHWDLL VIDEAHEGVD TFKTDQAFNK IRRNFTLHLS
     GTSFKALAKG DFTEEQIYNW SYADEQAAKY SWSLEQEEEN PYESLPQLNL FTYQMSQMIG
     EKLEKGAQID GENIDYVFDL SEFFATDDKG KFIHEHDVRN WLDTLSSNEK YPFSTKELRN
     ELKHTFWLLE RVASAKALKA LLEEHPIYEN YEIVLAAGDG RMSEEDDKVK LKSLDLVRKA
     IAENDKTITL SVGQLTTGVT IPEWTGVLML SNLKSPALYM QAAFRAQNPY SWSDNKGNHF
     RKERAYVFDF APERTLILFD EFANNLSLVT AAGRGTSATR EENIRELLNF FPIIAEDRAG
     KMVEIDAKAV LTTPRQIKAR EVLKRGFMSN LLFDNISGIF QASQTVLDIL NELPVEKEGK
     VQDSSDLLDF SDVTVDDEGN AVVDHEIVVN QQMRLFGEKV YGLGESVAEL VTKDEERTQK
     QLVNDLSKTV SSVIVEELKA DYSLKTRETE QIKKQITATL ENEIRKNDIE RKISEAHIKQ
     ELQQQLKEAN DKAQKDKIQE DLEKRLEENK LIHKEKLEQT LKKEVEKMPE KFIEQVEIKR
     VEQLKQSAQD EIRDHLRGFA RTIPSFIMAY GDQTLTLDNF DAFVPEHVFY EVTGITIDQF
     RYLRDGGQDF AGHLFDKATF DEAIQEFLRK KKELADYFKD QKEDIFDYIP PQKTNQIFTP
     KRVVKRMVDD LEKENPGIFD DPSKTFIDLY MKSGLYIAEL VKRLYNSNGL KEAFPNPEER
     LKHILEKQVY GFAPSEIIYN ISTNFIFGNL SKDISRKNFV LADTIPAAKE GSIQKLVDSY
     FENN
//