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Protein
Submitted name:

Alpha-amylase

Gene

amy

Organism
Streptococcus pneumoniae (strain ATCC BAA-255 / R6)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi103Calcium 1UniRule annotation1
Metal bindingi197Calcium 1UniRule annotation1
Metal bindingi203Calcium 1UniRule annotation1
Metal bindingi205Calcium 2UniRule annotation1
Active sitei234NucleophileUniRule annotation1
Metal bindingi238Calcium 1; via carbonyl oxygenUniRule annotation1
Active sitei264Proton donorUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosidaseImported, Hydrolase
LigandCalciumUniRule annotation, Metal-bindingUniRule annotation

Enzyme and pathway databases

BioCyciSPNE171101:G1FZH-1281-MONOMER

Protein family/group databases

CAZyiGH13 Glycoside Hydrolase Family 13

Names & Taxonomyi

Protein namesi
Submitted name:
Alpha-amylaseImported (EC:3.2.1.1Imported)
Gene namesi
Name:amyImported
Ordered Locus Names:spr1239Imported
OrganismiStreptococcus pneumoniae (strain ATCC BAA-255 / R6)Imported
Taxonomic identifieri171101 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
Proteomesi
  • UP000000586 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi171101.spr1239

Structurei

3D structure databases

ProteinModelPortaliQ8DPC8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 392AamyInterPro annotationAdd BLAST389

Sequence similaritiesi

Belongs to the glycosyl hydrolase 13 family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105E5K Bacteria
COG0366 LUCA
HOGENOMiHOG000094847
KOiK01176
OMAiVLNHKMG

Family and domain databases

Gene3Di2.60.40.1180, 1 hit
InterProiView protein in InterPro
IPR013776 A-amylase_thermo
IPR015237 Alpha-amylase_C_pro
IPR006046 Alpha_amylase
IPR006047 Glyco_hydro_13_cat_dom
IPR013780 Glyco_hydro_b
IPR017853 Glycoside_hydrolase_SF
PfamiView protein in Pfam
PF00128 Alpha-amylase, 1 hit
PF09154 DUF1939, 1 hit
PIRSFiPIRSF001021 Alph-amls_thrmst, 1 hit
PRINTSiPR00110 ALPHAAMYLASE
SMARTiView protein in SMART
SM00642 Aamy, 1 hit
SUPFAMiSSF51445 SSF51445, 1 hit

Sequencei

Sequence statusi: Complete.

Q8DPC8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQNQTLMQYF EWYLPHDGQH WTRLAENAPH LAHLGISHVW MPPAFKATNE
60 70 80 90 100
KDVGYGVYDL FDLGEFNQKG TVRTKYGFKE DYLQAIQALK AQGIQPMADV
110 120 130 140 150
VLNHKAAADH REAFQVIEVD PVDRTVELGE PFTINGWTSF TFDGRQDTYN
160 170 180 190 200
GFHWHWYHFT GTDYDAKRSK SGIYLIQGDN KGWANEELVD NENGNYDYLM
210 220 230 240 250
YADLDFKHPE VIQNIYDWAD WFMETTGVAG FRLDAVKHID SFFMRNFIRD
260 270 280 290 300
MKEKYGDDFY VFGEFWNSDK EANLDYLEKT EEHFDLVDVR LHQNLFEASQ
310 320 330 340 350
AGANYDLRGI FTDSLVELKP DKAVTFVDNH DTQRGQALES TVEEWFKPAA
360 370 380 390 400
YALILLRQDG LPCVFYGDYY GISGQYAQQD FKEILDRLLA IRKDLAYGEQ
410 420 430 440 450
NDYFDHANCI GWVRSGAENQ SPIAVLISND QENSKSMFVG QEWTNQTFVD
460 470 480
LLGSHQGQVT IDEEGYGQFP VSARSVSVWA VNTI
Length:484
Mass (Da):55,880
Last modified:March 1, 2003 - v1
Checksum:iDA511868187A0FFC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE007317 Genomic DNA Translation: AAL00043.1
PIRiF98026
RefSeqiNP_358832.1, NC_003098.1
WP_001181069.1, NC_003098.1

Genome annotation databases

EnsemblBacteriaiAAL00043; AAL00043; spr1239
GeneIDi934449
KEGGispr:spr1239
PATRICifig|171101.6.peg.1345

Similar proteinsi

Entry informationi

Entry nameiQ8DPC8_STRR6
AccessioniPrimary (citable) accession number: Q8DPC8
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: February 28, 2018
This is version 90 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health