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Protein
Submitted name:

1,4-beta-N-acetylmuramidase

Gene

lytC

Organism
Streptococcus pneumoniae (strain ATCC BAA-255 / R6)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei398N-acetyl-D-glucosamineCombined sources1
Binding sitei438N-acetyl-D-glucosamineCombined sources1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

GlycosidaseImported, Hydrolase

Protein family/group databases

CAZyiGH25. Glycoside Hydrolase Family 25.

Names & Taxonomyi

Protein namesi
Submitted name:
1,4-beta-N-acetylmuramidaseImported (EC:3.2.1.17Imported)
Gene namesi
Name:lytCImported
Ordered Locus Names:spr1431Imported
OrganismiStreptococcus pneumoniae (strain ATCC BAA-255 / R6)Imported
Taxonomic identifieri171101 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
Proteomesi
  • UP000000586 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 33Sequence analysisAdd BLAST33
ChainiPRO_500430760234 – 501Sequence analysisAdd BLAST468

Interactioni

Protein-protein interaction databases

STRINGi171101.spr1431.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2WW5X-ray1.61A34-501[»]
2WWCX-ray1.75A34-501[»]
2WWDX-ray2.25A34-501[»]
ProteinModelPortaliQ8DP07.
SMRiQ8DP07.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ8DP07.

Family & Domainsi

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG4108J4D. Bacteria.
COG5263. LUCA.
HOGENOMiHOG000285086.
KOiK01185.
OMAiAMIQNEW.

Family and domain databases

Gene3Di3.20.20.80. 1 hit.
InterProiIPR018337. Cell_wall/Cho-bd_repeat.
IPR002053. Glyco_hydro_25.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamiPF01473. CW_binding_1. 4 hits.
PF01183. Glyco_hydro_25. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 1 hit.
PROSITEiPS51170. CW. 6 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8DP07-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSVTFFIGEE RLKIKIGLAS ICLLGLATSH VAANETEVAK TSQDTTTASS
60 70 80 90 100
SSEQNQSSNK TQTSAEVQTN AAAYWDGDYY VKDDGSKAQS EWIFDNYYKA
110 120 130 140 150
WFYINSDGRY SQNEWHGNYY LKSGGYMAQN EWIYDSNYKS WFYLKSDGAY
160 170 180 190 200
AHQEWQLIGN KWYYFKKWGY MAKSQWQGSY FLNGQGAMIQ NEWLYDPAYS
210 220 230 240 250
AYFYLKSDGT YANQEWQKVG GKWYYFKKWG YMARNEWQGN YYLTGSGAMA
260 270 280 290 300
TDEVIMDGAR YIFAASGELK EKKDLNVGWV HRDGKRYFFN NREEQVGTEH
310 320 330 340 350
AKKIIDISEH NGRINDWKKV IDENKVDGVI VRLGYSGKED KELAHNIKEL
360 370 380 390 400
NRLGIPYGVY LYTYAENETD AENDAKQTIE LIKKYNMNLS YPIYYDVENW
410 420 430 440 450
EYVNKSKRAP SDTDTWVKII NKYMDTMKQA GYQNVYVYSY RSLLQTRLKH
460 470 480 490 500
PDILKHVNWV AAYTNALEWE NPYYSGEKGW QYTSSEYMKG IQGRVDVSVW

Y
Length:501
Mass (Da):58,681
Last modified:March 1, 2003 - v1
Checksum:iA2D74FC911241DA4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE007317 Genomic DNA. Translation: AAL00235.1.
PIRiF98050.
RefSeqiNP_359024.1. NC_003098.1.
WP_010976587.1. NC_003098.1.

Genome annotation databases

EnsemblBacteriaiAAL00235; AAL00235; spr1431.
GeneIDi933163.
KEGGispr:spr1431.
PATRICi19702862. VBIStrPne107296_1546.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE007317 Genomic DNA. Translation: AAL00235.1.
PIRiF98050.
RefSeqiNP_359024.1. NC_003098.1.
WP_010976587.1. NC_003098.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2WW5X-ray1.61A34-501[»]
2WWCX-ray1.75A34-501[»]
2WWDX-ray2.25A34-501[»]
ProteinModelPortaliQ8DP07.
SMRiQ8DP07.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi171101.spr1431.

Protein family/group databases

CAZyiGH25. Glycoside Hydrolase Family 25.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAL00235; AAL00235; spr1431.
GeneIDi933163.
KEGGispr:spr1431.
PATRICi19702862. VBIStrPne107296_1546.

Phylogenomic databases

eggNOGiENOG4108J4D. Bacteria.
COG5263. LUCA.
HOGENOMiHOG000285086.
KOiK01185.
OMAiAMIQNEW.

Miscellaneous databases

EvolutionaryTraceiQ8DP07.

Family and domain databases

Gene3Di3.20.20.80. 1 hit.
InterProiIPR018337. Cell_wall/Cho-bd_repeat.
IPR002053. Glyco_hydro_25.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamiPF01473. CW_binding_1. 4 hits.
PF01183. Glyco_hydro_25. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 1 hit.
PROSITEiPS51170. CW. 6 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ8DP07_STRR6
AccessioniPrimary (citable) accession number: Q8DP07
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: November 2, 2016
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.