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Q8DNM6 (TRPC_STRR6) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 53. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Indole-3-glycerol phosphate synthase
Short name=IGPS
EC=4.1.1.48
Gene names
Name:trpC
Ordered Locus Names:spr1634
OrganismStreptococcus pneumoniae (strain ATCC BAA-255 / R6)
Taxonomic identifier171101 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Lactobacillales › Streptococcaceae › Streptococcus

Protein attributes

Sequence length255 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate = 1-C-(3-indolyl)-glycerol 3-phosphate + CO2 + H2O. HAMAP MF_00134_B

Pathway

Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 4/5. HAMAP MF_00134_B

Sequence similarities

Belongs to the TrpC family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 255255Indole-3-glycerol phosphate synthase HAMAP MF_00134_B
PRO_0000154263

Sequences

Sequence LengthMass (Da)Tools
Q8DNM6 [UniParc].

Last modified March 1, 2003. Version 1.
Checksum: D0025AE1CCB3C530

FASTA25528,915
        10         20         30         40         50         60 
MSQEFLARIL EQKAREVEQM KLEQIQPLRQ TYRLAEFLKN HQDCLQVIAE VKKASPSLGD 

        70         80         90        100        110        120 
INLDVDIVQQ AQTYEENGAV MISVLTDEVF FKGHLDYLRE ISSQVEIPTL NKDFIIDEKQ 

       130        140        150        160        170        180 
IIRARNAGAT VILLIVAALS EERLKELYDY ATELGLEVLV ETHNLAELEV AHRLGAEIIG 

       190        200        210        220        230        240 
VNNRNLTTFE VDLQTSVDLA PYFEEGRYYI SESAIFTGQD AERLAPYFNG ILVGTALMQA 

       250 
ENVVQRIKEL QIDKG

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE007317 Genomic DNA. Translation: AAL00437.1.
PIRH98075.
RefSeqNP_359226.1. NC_003098.1.

3D structure databases

ProteinModelPortalQ8DNM6.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ8DNM6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBSTRT00000015589; EBSTRP00000014985; EBSTRG00000015589.
GeneID933756.
GenomeReviewsGene locus spr1634 in contig AE007317_GR.
KEGGspr:spr1634.
PATRIC19703296. VBIStrPne107296_1763.

Phylogenomic databases

eggNOGCOG0134.
GeneTreeEBGT00050000029214.
HOGENOMHBG540956.
OMAFETDINT.
PhylomeDBQ8DNM6.
ProtClustDBPRK00278.

Enzyme and pathway databases

BioCycSPNE171101:SPR1634-MONOMER.

Family and domain databases

HAMAPMF_00134_B. IGPS_B.
[Tree]
InterProIPR013785. Aldolase_TIM.
IPR013798. Indole-3-glycerol_P_synth.
IPR001468. Indole-3-GlycerolPSynthase_CS.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
Gene3DG3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KOK01609.
PfamPF00218. IGPS. 1 hit.
[Graphical view]
SUPFAMSSF51366. RibP_bind_barrel. 1 hit.
PROSITEPS00614. IGPS. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameTRPC_STRR6
AccessionPrimary (citable) accession number: Q8DNM6
Entry history
Integrated into UniProtKB/Swiss-Prot: October 24, 2003
Last sequence update: March 1, 2003
Last modified: January 25, 2012
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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