Q8DM05 (Q8DM05_THEEB) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Lipid A disaccharide synthase EMBL BAC07873.1

Gene names

Ordered Locus Names:

tll0321

Organism

Thermosynechococcus elongatus (strain BP-1)

Taxonomic identifier

197221 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Chroococcales › Thermosynechococcus

Protein attributes

Sequence length	387 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell By similarity. SAAS SAAS003835
Catalytic activity	UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine + 2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate = UDP + 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate. SAAS SAAS003835
Pathway	Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 5/6. SAAS SAAS003835

Ontologies

Keywords
Biological process	Lipid A biosynthesis SAAS SAAS003835 Lipid synthesis
Molecular function	Glycosyltransferase SAAS SAAS003835 Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	lipid A biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	lipid-A-disaccharide synthase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8DM05 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: F3B12FDF3E7E48F9	FASTA	387	42,272
	10 20 30 40 50 60 MAHLFISTGE VSGDLQGALL VKALYRLAAE RGMPLEISAL GGDRMAAAGA KVLFNTGSIG 70 80 90 100 110 120 SVGLLEALPL IKPTIALQLK ARRYLQQHPP DLVVLIDYIG GNVAMGQFIR RHFAIPIVYY 130 140 150 160 170 180 IAPQEWVWSH GLKTTQQIVA LSDRLLAIFP EEASYYRRHG ANVVWVGHPL LDRIAAAPSR 190 200 210 220 230 240 EVARQSLGIA ADELAIALLP LSRKQEIQSL LPLILGAATN IAKAYPQARF WLPLSLQQYR 250 260 270 280 290 300 PAIEAVLKQY PICVTLAEDS LQVLAAADLA IAKSGTVNLE TALLNVPQVV IYRVHPLSLW 310 320 330 340 350 360 LYQRFLKFNL QFVSPPNLLV GREIVPELLQ DRATIDNITA AAFALLDHPE KRLAMQAGYA 370 380 EMRAAMGTAG VVDRAATEIL NLIPQNG

References

[1]

"Complete genome structure of the thermophilic cyanobacterium Thermosynechococcus elongatus BP-1." Nakamura Y., Kaneko T., Sato S., Ikeuchi M., Katoh H., Sasamoto S., Watanabe A., Iriguchi M., Kawashima K., Kimura T., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A., Nakazaki N., Shimpo S., Sugimoto M. , Takeuchi C., Yamada M., Tabata S. DNA Res. 9:123-130(2002) [PubMed: 12240834] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: BP-1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000039 Genomic DNA. Translation: BAC07873.1.
RefSeq	NP_681111.1. NC_004113.1.
3D structure databases
ProteinModelPortal	Q8DM05.
ModBase	Search...
Protein-protein interaction databases
STRING	Q8DM05.
Protein family/group databases
CAZy	GT19. Glycosyltransferase Family 19.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1012710.
GenomeReviews	Gene locus tll0321 in contig BA000039_GR.
KEGG	tel:tll0321.
NMPDR	fig|197221.1.peg.320.
PATRIC	23925860. VBITheElo119873_0338.
Phylogenomic databases
HOGENOM	HBG584837.
OMA	RATIDNI.
ProtClustDB	PRK00025.
Enzyme and pathway databases
BioCyc	TELO197221:TLL0321-MONOMER.
Family and domain databases
InterPro	IPR003835. Glyco_trans_19. [Graphical view]
KO	K00748.
Pfam	PF02684. LpxB. 1 hit. [Graphical view]
TIGRFAMs	TIGR00215. LpxB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q8DM05_THEEB

Accession

Primary (citable) accession number: Q8DM05

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2003
Last sequence update:	March 1, 2003
Last modified:	December 14, 2011
This is version 47 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)