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Q8DLY3 (AROA_THEEB) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 57. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
3-phosphoshikimate 1-carboxyvinyltransferase
EC=2.5.1.19
Alternative name(s):
5-enolpyruvylshikimate-3-phosphate synthase
Short name=EPSP synthase
Short name=EPSPS
Gene names
Name:aroA
Ordered Locus Names:tlr0343
OrganismThermosynechococcus elongatus (strain BP-1)
Taxonomic identifier197221 [NCBI]
Taxonomic lineageBacteria › Cyanobacteria › Chroococcales › Thermosynechococcus

Protein attributes

Sequence length440 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Phosphoenolpyruvate + 3-phosphoshikimate = phosphate + 5-O-(1-carboxyvinyl)-3-phosphoshikimate. HAMAP MF_00210

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 6/7. HAMAP MF_00210

Subunit structure

Monomer By similarity. HAMAP MF_00210

Subcellular location

Cytoplasm By similarity HAMAP MF_00210.

Sequence similarities

Belongs to the EPSP synthase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Cellular componentCytoplasm
   Molecular functionTransferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular function3-phosphoshikimate 1-carboxyvinyltransferase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 4404403-phosphoshikimate 1-carboxyvinyltransferase HAMAP MF_00210
PRO_0000088310

Sequences

Sequence LengthMass (Da)Tools
Q8DLY3 [UniParc].

Last modified March 1, 2003. Version 1.
Checksum: 14F4687442A42E58

FASTA44046,574
        10         20         30         40         50         60 
MAVIQITSDD TWQIQADGHP LRGTLQVPGD KSISHRALML GAMAEGTTQI TGLLVGEDTC 

        70         80         90        100        110        120 
STASCFRALG AEISPLNATA VTVQGLGMGR LQEPGDVMNA GNSGTTMRLL LGVLAAQTGR 

       130        140        150        160        170        180 
FFTLTGDASL RSRPMARVVT PLLQMGAQIW GRQHHSRAPL AILGQPLEPI TYYSPIASAQ 

       190        200        210        220        230        240 
VKSALLLAAL HTEGTTLIRE PHRSRDHSER MLQAFGARLS VDEATCTVSL EGPAVLKGQK 

       250        260        270        280        290        300 
VIVPGDISSA AFWLVAASII PDSELLLTNV GVNPTRTGIL DVLWAMGAEI TLENERLVTG 

       310        320        330        340        350        360 
EPVADLRVRS ARLKSTRIGG ELIPRLIDEI PILAVAAAFA EGVTEIRDAA ELRVKESDRL 

       370        380        390        400        410        420 
KAVATELQKM GAKVTELSDG LDIQGGGPLQ GTHLETYGDH RMAMSLAIAA LNAKGTSEIH 

       430        440 
NASAAAVSYP EFVTVLQQIA

« Hide

References

[1]"Complete genome structure of the thermophilic cyanobacterium Thermosynechococcus elongatus BP-1."
Nakamura Y., Kaneko T., Sato S., Ikeuchi M., Katoh H., Sasamoto S., Watanabe A., Iriguchi M., Kawashima K., Kimura T., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A., Nakazaki N., Shimpo S., Sugimoto M. expand/collapse author list , Takeuchi C., Yamada M., Tabata S.
DNA Res. 9:123-130(2002) [PubMed: 12240834] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: BP-1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BA000039 Genomic DNA. Translation: BAC07895.1.
RefSeqNP_681133.1. NC_004113.1.

3D structure databases

ProteinModelPortalQ8DLY3.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ8DLY3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1012588.
GenomeReviewsGene locus tlr0343 in contig BA000039_GR.
KEGGtel:tlr0343.
NMPDRfig|197221.1.peg.342.
PATRIC23925906. VBITheElo119873_0360.

Phylogenomic databases

eggNOGCOG0128.
HOGENOMHBG646626.
OMAGEDPRST.
ProtClustDBPRK02427.

Enzyme and pathway databases

BioCycTELO197221:TLR0343-MONOMER.

Family and domain databases

HAMAPMF_00210. EPSP_synth.
[Tree]
InterProIPR001986. Enolpyruvate_Tfrase_dom.
IPR006264. EPSP_synthase.
IPR023193. EPSP_synthase_CS.
IPR013792. RNA3'P_cycl/enolpyr_Trfase_a/b.
[Graphical view]
Gene3DG3DSA:3.65.10.10. EPSP_synthase. 2 hits.
KOK00800.
PfamPF00275. EPSP_synthase. 1 hit.
[Graphical view]
PIRSFPIRSF000505. EPSPS. 1 hit.
SUPFAMSSF55205. RNA3'_cycl/enolpyr_transf_A/B. 1 hit.
TIGRFAMsTIGR01356. AroA. 1 hit.
PROSITEPS00104. EPSP_SYNTHASE_1. False negative.
PS00885. EPSP_SYNTHASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameAROA_THEEB
AccessionPrimary (citable) accession number: Q8DLY3
Entry history
Integrated into UniProtKB/Swiss-Prot: June 6, 2003
Last sequence update: March 1, 2003
Last modified: January 25, 2012
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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