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Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Thermosynechococcus elongatus (strain BP-1)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi: glycolysis

This protein is involved in step 2 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose.UniRule annotation
Proteins known to be involved in the 4 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Glucose-6-phosphate isomerase (pgi)
  3. ATP-dependent 6-phosphofructokinase (pfkA)
  4. no protein annotated in this organism
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose, the pathway glycolysis and in Carbohydrate degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei322Proton donorUniRule annotation1
Active sitei351UniRule annotation1
Active sitei455UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processGluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciTELO197221:G1G3I-733-MONOMER
UniPathwayiUPA00109; UER00181

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgiUniRule annotation
Ordered Locus Names:tll0717
OrganismiThermosynechococcus elongatus (strain BP-1)
Taxonomic identifieri197221 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaSynechococcalesSynechococcaceaeThermosynechococcus
Proteomesi
  • UP000000440 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001807521 – 529Glucose-6-phosphate isomeraseAdd BLAST529

Interactioni

Protein-protein interaction databases

STRINGi197221.tll0717

Structurei

3D structure databases

ProteinModelPortaliQ8DKY2
SMRiQ8DKY2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C89 Bacteria
COG0166 LUCA
HOGENOMiHOG000131425
KOiK01810
OMAiTNSQHAF
OrthoDBiPOG091H04C3

Family and domain databases

CDDicd05015 SIS_PGI_1, 1 hit
cd05016 SIS_PGI_2, 1 hit
HAMAPiMF_00473 G6P_isomerase, 1 hit
InterProiView protein in InterPro
IPR001672 G6P_Isomerase
IPR018189 Phosphoglucose_isomerase_CS
IPR035476 SIS_PGI_1
IPR035482 SIS_PGI_2
PANTHERiPTHR11469 PTHR11469, 1 hit
PfamiView protein in Pfam
PF00342 PGI, 2 hits
PRINTSiPR00662 G6PISOMERASE
PROSITEiView protein in PROSITE
PS00174 P_GLUCOSE_ISOMERASE_2, 1 hit
PS51463 P_GLUCOSE_ISOMERASE_3, 1 hit

Sequencei

Sequence statusi: Complete.

Q8DKY2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDALALWQHY QDWLYYHPEL EFYVDVSRMG LTPEVVHRLE PAFERAFEQM
60 70 80 90 100
KELEAGAIAN PDEGRMVGHY WLRDPDLAPS PELRSQIRDA IAQVKQFSQQ
110 120 130 140 150
VHSGAIAPPQ GGHFTEILSI GIGGSALGPQ FVAAALAPVH PPLNIHFLDN
160 170 180 190 200
TDPAGFERVF AELGDRLRTT LVLVISKSGG TPETRNGMLE AQARFQRAGL
210 220 230 240 250
AFADHAVAVT LPGSGLAQVA ESNGWLAIFP MFDWVGGRTS ELSTVGLLPA
260 270 280 290 300
ALQGIDIDDL LMGAKLMDQA TRVPNIRQNP AALLALAWHH AGKGRGEKDM
310 320 330 340 350
VILPYKDSLL LFSRYLQQLV MESLGKETDL NGNIVHQGIA VYGNKGTTDQ
360 370 380 390 400
HAYVQQLRDG LPNFFVTFIE VLRDGQEPSI EVEPGITAGD YLSGLLLGTR
410 420 430 440 450
QALYEKNRPS LTVTIPEVTP KTVGALIALY ERAVGLYGFL VNINAYHQPG
460 470 480 490 500
VEAGKKAAAA NLALQRQIVK VLEQSDEPLD LGAIAGAINA PDQLERIYLI
510 520
LRHLAANDRG IEQLGDPAQP SQLQFRWQR
Length:529
Mass (Da):57,908
Last modified:March 1, 2003 - v1
Checksum:i97977FE8F4271991
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000039 Genomic DNA Translation: BAC08268.1
RefSeqiNP_681506.1, NC_004113.1
WP_011056564.1, NC_004113.1

Genome annotation databases

EnsemblBacteriaiBAC08268; BAC08268; BAC08268
GeneIDi1011938
KEGGitel:tll0717
PATRICifig|197221.4.peg.757

Similar proteinsi

Entry informationi

Entry nameiG6PI_THEEB
AccessioniPrimary (citable) accession number: Q8DKY2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 23, 2003
Last sequence update: March 1, 2003
Last modified: February 28, 2018
This is version 80 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome