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Q8DKY2 (G6PI_THEEB) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 62. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucose-6-phosphate isomerase

Short name=GPI
EC=5.3.1.9
Alternative name(s):
Phosphoglucose isomerase
Short name=PGI
Phosphohexose isomerase
Short name=PHI
Gene names
Name:pgi
Ordered Locus Names:tll0717
OrganismThermosynechococcus elongatus (strain BP-1) [Reference proteome] [HAMAP]
Taxonomic identifier197221 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesThermosynechococcus

Protein attributes

Sequence length529 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP-Rule MF_00473

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP-Rule MF_00473

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00473.

Sequence similarities

Belongs to the GPI family.

Ontologies

Keywords
   Biological processGluconeogenesis
Glycolysis
   Cellular componentCytoplasm
   Molecular functionIsomerase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processgluconeogenesis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glycolysis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionglucose-6-phosphate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 529529Glucose-6-phosphate isomerase HAMAP-Rule MF_00473
PRO_0000180752

Sites

Active site3221Proton donor By similarity
Active site3511 By similarity
Active site4551 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q8DKY2 [UniParc].

Last modified March 1, 2003. Version 1.
Checksum: 97977FE8F4271991

FASTA52957,908
        10         20         30         40         50         60 
MDALALWQHY QDWLYYHPEL EFYVDVSRMG LTPEVVHRLE PAFERAFEQM KELEAGAIAN 

        70         80         90        100        110        120 
PDEGRMVGHY WLRDPDLAPS PELRSQIRDA IAQVKQFSQQ VHSGAIAPPQ GGHFTEILSI 

       130        140        150        160        170        180 
GIGGSALGPQ FVAAALAPVH PPLNIHFLDN TDPAGFERVF AELGDRLRTT LVLVISKSGG 

       190        200        210        220        230        240 
TPETRNGMLE AQARFQRAGL AFADHAVAVT LPGSGLAQVA ESNGWLAIFP MFDWVGGRTS 

       250        260        270        280        290        300 
ELSTVGLLPA ALQGIDIDDL LMGAKLMDQA TRVPNIRQNP AALLALAWHH AGKGRGEKDM 

       310        320        330        340        350        360 
VILPYKDSLL LFSRYLQQLV MESLGKETDL NGNIVHQGIA VYGNKGTTDQ HAYVQQLRDG 

       370        380        390        400        410        420 
LPNFFVTFIE VLRDGQEPSI EVEPGITAGD YLSGLLLGTR QALYEKNRPS LTVTIPEVTP 

       430        440        450        460        470        480 
KTVGALIALY ERAVGLYGFL VNINAYHQPG VEAGKKAAAA NLALQRQIVK VLEQSDEPLD 

       490        500        510        520 
LGAIAGAINA PDQLERIYLI LRHLAANDRG IEQLGDPAQP SQLQFRWQR 

« Hide

References

[1]"Complete genome structure of the thermophilic cyanobacterium Thermosynechococcus elongatus BP-1."
Nakamura Y., Kaneko T., Sato S., Ikeuchi M., Katoh H., Sasamoto S., Watanabe A., Iriguchi M., Kawashima K., Kimura T., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A., Nakazaki N., Shimpo S., Sugimoto M. expand/collapse author list , Takeuchi C., Yamada M., Tabata S.
DNA Res. 9:123-130(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: BP-1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000039 Genomic DNA. Translation: BAC08268.1.
RefSeqNP_681506.1. NC_004113.1.

3D structure databases

ProteinModelPortalQ8DKY2.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING197221.tll0717.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAC08268; BAC08268; BAC08268.
GeneID1011938.
KEGGtel:tll0717.
PATRIC23926712. VBITheElo119873_0757.

Phylogenomic databases

eggNOGCOG0166.
HOGENOMHOG000131425.
KOK01810.
OMARQVGHYW.
OrthoDBEOG64R61J.
ProtClustDBPRK14096.

Enzyme and pathway databases

UniPathwayUPA00109; UER00181.

Family and domain databases

HAMAPMF_00473. G6P_isomerase.
InterProIPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERPTHR11469. PTHR11469. 1 hit.
PfamPF00342. PGI. 1 hit.
[Graphical view]
PRINTSPR00662. G6PISOMERASE.
PROSITEPS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG6PI_THEEB
AccessionPrimary (citable) accession number: Q8DKY2
Entry history
Integrated into UniProtKB/Swiss-Prot: May 23, 2003
Last sequence update: March 1, 2003
Last modified: February 19, 2014
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways