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Q8DKN4 (SYR_THEEB) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 70. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:tll0826
OrganismThermosynechococcus elongatus (strain BP-1) [Reference proteome] [HAMAP]
Taxonomic identifier197221 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesThermosynechococcus

Protein attributes

Sequence length584 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 584584Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_0000151624

Regions

Motif125 – 13511"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
Q8DKN4 [UniParc].

Last modified March 1, 2003. Version 1.
Checksum: D2E5B5314EC98CF3

FASTA58465,503
        10         20         30         40         50         60 
MVAPIKILGD RLRRALQAAL PLDTYPQPLL VPASQVKFGD YQSNVCLSLA KQLGKAPREL 

        70         80         90        100        110        120 
AQEVVPHLEV EDLCQPVEIA GPGFLNFRLK PEFLAATLQA ARGSDRLGIP PAREPRRVVV 

       130        140        150        160        170        180 
DFSSPNIAKE MHVGHLRSTI IGDCIARILE FQGHTVLRLN HVGDWGTQFG MLIAYLDEVY 

       190        200        210        220        230        240 
PDALTTANAL DLGDLVTFYK KAKQRFDSDP EFQQKARAKV VALQQGEEQS RRAWQLLCEQ 

       250        260        270        280        290        300 
SRREFQKIYD LLDIQLTERG ESFYNPFLPA VIEDLAACGL LVEDQGAKVV FLEGFTNKEG 

       310        320        330        340        350        360 
QPQPLIIQKS DGGYNYATTD LAALRYRIDK DQADWIIYVT DVGQSTHFAQ VFQVAQRAGW 

       370        380        390        400        410        420 
VPPHVTLTHV PFGLVLGEDG KRLKTRSGET IRLIDLLTEA IARSRADLEQ RLATEGRTES 

       430        440        450        460        470        480 
PEFIDTVARA IGIGAVKYAD LSQNRNSNYV FSYDKMLSLQ GNTAPYLLYA YVRVQGLTRR 

       490        500        510        520        530        540 
GDIDWCTLSP DSPLLLEDET EQHLAKHLVQ LEETLDLVST ELLPNRLCQY LFELSQLFNQ 

       550        560        570        580 
FYDRCPILSA PQPTKQSRLT LAYLTAQTLK LGLSLLGIPV LDRI 

« Hide

References

[1]"Complete genome structure of the thermophilic cyanobacterium Thermosynechococcus elongatus BP-1."
Nakamura Y., Kaneko T., Sato S., Ikeuchi M., Katoh H., Sasamoto S., Watanabe A., Iriguchi M., Kawashima K., Kimura T., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A., Nakazaki N., Shimpo S., Sugimoto M. expand/collapse author list , Takeuchi C., Yamada M., Tabata S.
DNA Res. 9:123-130(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: BP-1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000039 Genomic DNA. Translation: BAC08377.1.
RefSeqNP_681615.1. NC_004113.1.

3D structure databases

ProteinModelPortalQ8DKN4.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING197221.tll0826.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAC08377; BAC08377; BAC08377.
GeneID1011600.
KEGGtel:tll0826.
PATRIC23926940. VBITheElo119873_0870.

Phylogenomic databases

eggNOGCOG0018.
HOGENOMHOG000247212.
KOK01887.
OMAMEHMGFG.
OrthoDBEOG6JB13C.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYR_THEEB
AccessionPrimary (citable) accession number: Q8DKN4
Entry history
Integrated into UniProtKB/Swiss-Prot: August 22, 2003
Last sequence update: March 1, 2003
Last modified: May 14, 2014
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries