Reviewed, UniProtKB/Swiss-Prot Q8DKK1 (PPNK1_THEEB)

Names and origin

Protein names

Recommended name:
    Probable inorganic polyphosphate/ATP-NAD kinase 1
      Short name=Poly(P)/ATP NAD kinase 1
    EC=2.7.1.23

Gene names

Name:	ppnK1
Ordered Locus Names:	tll0858

Organism

Thermosynechococcus elongatus (strain BP-1) [Complete proteome] [HAMAP]

Taxonomic identifier

197221 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Chroococcales › Thermosynechococcus

Protein attributes

Sequence length	307 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus By similarity.
Catalytic activity	ATP + NAD+ = ADP + NADP+. HAMAP MF_00361
Cofactor	Divalent metal ions By similarity.
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the NAD kinase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	ATP-binding NAD NADP Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW NAD+ kinase activity Inferred from electronic annotation. Source: HAMAP metal ion binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 307	307	Probable inorganic polyphosphate/ATP-NAD kinase 1 HAMAP MF_00361		PRO_0000120676

Sequences

	Sequence		Length	Mass (Da)
	Q8DKK1-1 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: E9002ECD7605593D	FASTA	307	33,282
	10 20 30 40 50 60 MKAGIIYNEG KPLAVELAAH VRRILELQGW EVHMATGIGG ILGYSRPDSP VCHTPIDQLV 70 80 90 100 110 120 PPGFDASMAF AVVLGGDGTV LSAFRQLAPC EIPLLTINTG HLGFLTEGYV ADLEPALDQV 130 140 150 160 170 180 LRGDYTIEDR TMLTVQVLRD QTVIWEALSL NEMVIHKEPL TGMCHFEVDV GAHARVDIAA 190 200 210 220 230 240 DGLILSTPTG STAYALSAGG PVITPGVAAL QLVPICPHSL ASRALVFSNS EPVWIYPANP 250 260 270 280 290 300 FKHLILVVDG NAGCYIQPED QVFVQRAPYR ARFIRLRAPE FFHVLQQKLG WGLPHVAKPR AKKSTDS

References

[1]

"Complete genome structure of the thermophilic cyanobacterium Thermosynechococcus elongatus BP-1." Nakamura Y., Kaneko T., Sato S., Ikeuchi M., Katoh H., Sasamoto S., Watanabe A., Iriguchi M., Kawashima K., Kimura T., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A., Nakazaki N., Shimpo S., Sugimoto M. , Takeuchi C., Yamada M., Tabata S. DNA Res. 9:123-130(2002) [PubMed: 12240834] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	BA000039 Genomic DNA. Translation: BAC08410.1.
RefSeq	NP_681648.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	1011490.
GenomeReviews	Gene locus tll0858 in contig BA000039_GR.
KEGG	tel:tll0858.
NMPDR	fig|197221.1.peg.857.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q8DKK1.
Enzyme and pathway databases
BioCyc	TELO197221:TLL0858-MON.
BRENDA	2.7.1.23. 277225.
Family and domain databases
HAMAP	MF_00361. [Tree]
InterPro	IPR017437. ATP-NAD_kinase_PpnK-typ_all-b. IPR002504. ATP_NADK. [Graphical view]
Gene3D	G3DSA:2.60.200.30. ATP-NAD_kinase_PpnK-typ. 1 hit.
PANTHER	PTHR20275. ATP_NADK. 1 hit.
Pfam	PF01513. NAD_kinase. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PPNK1_THEEB

Accession

Primary (citable) accession number: Q8DKK1

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 22, 2003
Last sequence update:	March 1, 2003
Last modified:	June 16, 2009
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)