SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q8DKK1

- NADK1_THEEB

UniProt

Q8DKK1 - NADK1_THEEB

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
NAD kinase 1
Gene
nadK1, tll0858
Organism
Thermosynechococcus elongatus (strain BP-1)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP By similarity.UniRule annotation

Catalytic activityi

ATP + NAD+ = ADP + NADP+.UniRule annotation

Cofactori

Divalent metal ions By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei77 – 771Proton acceptor By similarity
Binding sitei181 – 1811NAD By similarity
Binding sitei251 – 2511NAD By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi77 – 782NAD By similarity
Nucleotide bindingi151 – 1522NAD By similarity
Nucleotide bindingi192 – 1976NAD By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. NAD+ kinase activity Source: UniProtKB-HAMAP
  3. metal ion binding Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

  1. NAD metabolic process Source: InterPro
  2. NADP biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Ligandi

ATP-binding, NAD, NADP, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
NAD kinase 1 (EC:2.7.1.23)
Alternative name(s):
ATP-dependent NAD kinase 1
Gene namesi
Name:nadK1
Ordered Locus Names:tll0858
OrganismiThermosynechococcus elongatus (strain BP-1)
Taxonomic identifieri197221 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesThermosynechococcus
ProteomesiUP000000440: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 307307NAD kinase 1UniRule annotation
PRO_0000120676Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi197221.tll0858.

Structurei

3D structure databases

ProteinModelPortaliQ8DKK1.

Family & Domainsi

Sequence similaritiesi

Belongs to the NAD kinase family.

Phylogenomic databases

eggNOGiCOG0061.
HOGENOMiHOG000227222.
KOiK00858.
OMAiPRKTKFV.
OrthoDBiEOG6PZXDR.

Family and domain databases

Gene3Di2.60.200.30. 1 hit.
3.40.50.10330. 1 hit.
HAMAPiMF_00361. NAD_kinase.
InterProiIPR017438. ATP-NAD_kinase_dom_1.
IPR016064. ATP-NAD_kinase_PpnK-typ.
IPR017437. ATP-NAD_kinase_PpnK-typ_all-b.
IPR002504. PolyP/ATP_NADK.
[Graphical view]
PANTHERiPTHR20275. PTHR20275. 1 hit.
PfamiPF01513. NAD_kinase. 1 hit.
[Graphical view]
SUPFAMiSSF111331. SSF111331. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8DKK1-1 [UniParc]FASTAAdd to Basket

« Hide

MKAGIIYNEG KPLAVELAAH VRRILELQGW EVHMATGIGG ILGYSRPDSP    50
VCHTPIDQLV PPGFDASMAF AVVLGGDGTV LSAFRQLAPC EIPLLTINTG 100
HLGFLTEGYV ADLEPALDQV LRGDYTIEDR TMLTVQVLRD QTVIWEALSL 150
NEMVIHKEPL TGMCHFEVDV GAHARVDIAA DGLILSTPTG STAYALSAGG 200
PVITPGVAAL QLVPICPHSL ASRALVFSNS EPVWIYPANP FKHLILVVDG 250
NAGCYIQPED QVFVQRAPYR ARFIRLRAPE FFHVLQQKLG WGLPHVAKPR 300
AKKSTDS 307
Length:307
Mass (Da):33,282
Last modified:March 1, 2003 - v1
Checksum:iE9002ECD7605593D
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000039 Genomic DNA. Translation: BAC08410.1.
RefSeqiNP_681648.1. NC_004113.1.

Genome annotation databases

EnsemblBacteriaiBAC08410; BAC08410; BAC08410.
GeneIDi1011490.
KEGGitel:tll0858.
PATRICi23927006. VBITheElo119873_0903.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000039 Genomic DNA. Translation: BAC08410.1 .
RefSeqi NP_681648.1. NC_004113.1.

3D structure databases

ProteinModelPortali Q8DKK1.
ModBasei Search...

Protein-protein interaction databases

STRINGi 197221.tll0858.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAC08410 ; BAC08410 ; BAC08410 .
GeneIDi 1011490.
KEGGi tel:tll0858.
PATRICi 23927006. VBITheElo119873_0903.

Phylogenomic databases

eggNOGi COG0061.
HOGENOMi HOG000227222.
KOi K00858.
OMAi PRKTKFV.
OrthoDBi EOG6PZXDR.

Family and domain databases

Gene3Di 2.60.200.30. 1 hit.
3.40.50.10330. 1 hit.
HAMAPi MF_00361. NAD_kinase.
InterProi IPR017438. ATP-NAD_kinase_dom_1.
IPR016064. ATP-NAD_kinase_PpnK-typ.
IPR017437. ATP-NAD_kinase_PpnK-typ_all-b.
IPR002504. PolyP/ATP_NADK.
[Graphical view ]
PANTHERi PTHR20275. PTHR20275. 1 hit.
Pfami PF01513. NAD_kinase. 1 hit.
[Graphical view ]
SUPFAMi SSF111331. SSF111331. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: BP-1.

Entry informationi

Entry nameiNADK1_THEEB
AccessioniPrimary (citable) accession number: Q8DKK1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 22, 2003
Last sequence update: March 1, 2003
Last modified: July 9, 2014
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi