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Q8DKH4 (Q8DKH4_THEEB) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 57. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Peptide methionine sulfoxide reductase MsrA HAMAP MF_01401
Short name=Protein-methionine-S-oxide reductase HAMAP MF_01401
EC=1.8.4.11 HAMAP MF_01401
Alternative name(s):
Peptide-methionine (S)-S-oxide reductase HAMAP MF_01401
Gene names
Name:msrA HAMAP MF_01401
Ordered Locus Names:tll0885
OrganismThermosynechococcus elongatus (strain BP-1)
Taxonomic identifier197221 [NCBI]
Taxonomic lineageBacteria › Cyanobacteria › Chroococcales › Thermosynechococcus

Protein attributes

Sequence length224 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine By similarity. HAMAP MF_01401

Catalytic activity

L-methionine + thioredoxin disulfide + H2O = L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401 SAAS SAAS002569

Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401 SAAS SAAS002569

Sequence similarities

Belongs to the MsrA Met sulfoxide reductase family. HAMAP MF_01401

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site571 By similarity HAMAP MF_01401

Sequences

Sequence LengthMass (Da)Tools
Q8DKH4 [UniParc].

Last modified March 1, 2003. Version 1.
Checksum: 027C067D516507F6

FASTA22424,892
        10         20         30         40         50         60 
MGFFGFKNKK LTMPSPSEAL PGRAEPMPVP KAHLVNGHPL TPPYPEGMEL AMFGMGCFWG 

        70         80         90        100        110        120 
AERKFWQVPG VYVTAVGYAG GYTPNPTYEE VCTGMTGHNE VVRVVFDPQI VSYEELLKVF 

       130        140        150        160        170        180 
WENHDPTQGM RQGNDVGTQY RSGIYYYSPE QKALAEASRD RYQAALTAAG YGTITTEILP 

       190        200        210        220 
APEFYFAEPY HQQYLQRNVN GYCGLGGTKV PYELMGATPA FRGD

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References

[1]"Complete genome structure of the thermophilic cyanobacterium Thermosynechococcus elongatus BP-1."
Nakamura Y., Kaneko T., Sato S., Ikeuchi M., Katoh H., Sasamoto S., Watanabe A., Iriguchi M., Kawashima K., Kimura T., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A., Nakazaki N., Shimpo S., Sugimoto M. expand/collapse author list , Takeuchi C., Yamada M., Tabata S.
DNA Res. 9:123-130(2002) [PubMed: 12240834] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: BP-1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BA000039 Genomic DNA. Translation: BAC08437.1.
RefSeqNP_681675.1. NC_004113.1.

3D structure databases

HSSPHSSP built from PDB template 1FF3 based on UniProtKB P27110.
ProteinModelPortalQ8DKH4.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ8DKH4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1011437.
GenomeReviewsGene locus tll0885 in contig BA000039_GR.
KEGGtel:tll0885.
NMPDRfig|197221.1.peg.884.
PATRIC23927062. VBITheElo119873_0931.

Phylogenomic databases

HOGENOMHBG748152.
OMASAIYCTT.
ProtClustDBPRK00058.

Enzyme and pathway databases

BioCycTELO197221:TLL0885-MONOMER.

Family and domain databases

HAMAPMF_01401. MsrA.
[Tree]
InterProIPR002569. Peptide_Met_Sox_Rdtase_MsrA.
[Graphical view]
Gene3DG3DSA:3.30.1060.10. MsrA. 1 hit.
KOK07304.
PfamPF01625. PMSR. 1 hit.
[Graphical view]
SUPFAMSSF55068. MsrA. 1 hit.
TIGRFAMsTIGR00401. MsrA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ8DKH4_THEEB
AccessionPrimary (citable) accession number: Q8DKH4
Entry history
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: December 14, 2011
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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