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Protein

Peptide methionine sulfoxide reductase MsrB

Gene

msrB

Organism
Thermosynechococcus elongatus (strain BP-1)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (R)-S-oxide + thioredoxin.UniRule annotation

Cofactori

Zn2+UniRule annotationNote: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi47ZincPROSITE-ProRule annotation1
Metal bindingi50ZincPROSITE-ProRule annotation1
Metal bindingi96ZincPROSITE-ProRule annotation1
Metal bindingi99ZincPROSITE-ProRule annotation1
Active sitei119NucleophilePROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase
LigandMetal-binding, Zinc

Enzyme and pathway databases

BioCyciTELO197221:G1G3I-1236-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Peptide methionine sulfoxide reductase MsrBUniRule annotation (EC:1.8.4.12UniRule annotation)
Alternative name(s):
Peptide-methionine (R)-S-oxide reductaseUniRule annotation
Gene namesi
Name:msrBUniRule annotation
Ordered Locus Names:tlr1214
OrganismiThermosynechococcus elongatus (strain BP-1)
Taxonomic identifieri197221 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaSynechococcalesSynechococcaceaeThermosynechococcus
Proteomesi
  • UP000000440 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001403111 – 135Peptide methionine sulfoxide reductase MsrBAdd BLAST135

Proteomic databases

PRIDEiQ8DJK9

Interactioni

Protein-protein interaction databases

STRINGi197221.tlr1214

Structurei

3D structure databases

ProteinModelPortaliQ8DJK9
SMRiQ8DJK9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini8 – 130MsrBPROSITE-ProRule annotationAdd BLAST123

Sequence similaritiesi

Belongs to the MsrB Met sulfoxide reductase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105E0X Bacteria
COG0229 LUCA
HOGENOMiHOG000243424
KOiK07305
OMAiQYVVTRE
OrthoDBiPOG091H064P

Family and domain databases

HAMAPiMF_01400 MsrB, 1 hit
InterProiView protein in InterPro
IPR028427 Met_Sox_Rdtase
IPR002579 Met_Sox_Rdtase_MsrB
IPR011057 Mss4-like_sf
PANTHERiPTHR10173 PTHR10173, 1 hit
PfamiView protein in Pfam
PF01641 SelR, 1 hit
SUPFAMiSSF51316 SSF51316, 1 hit
TIGRFAMsiTIGR00357 TIGR00357, 1 hit
PROSITEiView protein in PROSITE
PS51790 MSRB, 1 hit

Sequencei

Sequence statusi: Complete.

Q8DJK9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTKVVKTDAE WQAQLTPEQY YVTRKKGTER AFTGCYWNNK KPGLYSCVCC
60 70 80 90 100
GTPLFRSETK YDSGTGWPSF WQPLDPNNIR MERDLSHGMV RTEVLCAVCD
110 120 130
AHLGHVFEDG PPPTGLRYCI NSAALAFVPE SAASS
Length:135
Mass (Da):15,087
Last modified:March 1, 2003 - v1
Checksum:i68CBA46572BAAE59
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000039 Genomic DNA Translation: BAC08766.1
RefSeqiNP_682004.1, NC_004113.1
WP_011057056.1, NC_004113.1

Genome annotation databases

EnsemblBacteriaiBAC08766; BAC08766; BAC08766
GeneIDi1011696
KEGGitel:tlr1214
PATRICifig|197221.4.peg.1278

Similar proteinsi

Entry informationi

Entry nameiMSRB_THEEB
AccessioniPrimary (citable) accession number: Q8DJK9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 16, 2003
Last sequence update: March 1, 2003
Last modified: May 23, 2018
This is version 93 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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