Q8DJE9 (FBSB_THEEB) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
D-fructose 1,6-bisphosphatase class 2/sedoheptulose 1,7-bisphosphatase
Short name=FBPase class 2/SBPase
EC=3.1.3.11
EC=3.1.3.37

Gene names

Ordered Locus Names:

tll1276

Organism

Thermosynechococcus elongatus (strain BP-1)

Taxonomic identifier

197221 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Chroococcales › Thermosynechococcus

Protein attributes

Sequence length	347 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the hydrolysis of fructose 1,6-bisphosphate (Fru 1,6-P2) and sedoheptulose 1,7-bisphosphate (Sed 1,7-P2) to fructose 6-phosphate and sedoheptulose 7-phosphate, respectively By similarity.
Catalytic activity	D-fructose 1,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate. Sedoheptulose 1,7-bisphosphate + H2O = sedoheptulose 7-phosphate + phosphate.
Cofactor	Manganese By similarity.
Pathway	Carbohydrate biosynthesis; Calvin cycle.
Subunit structure	Homotetramer By similarity.
Sequence similarities	Belongs to the FBPase class 2 family.

Ontologies

Keywords
Biological process	Calvin cycle Carbohydrate metabolism
Ligand	Manganese Metal-binding
Molecular function	Hydrolase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	glycerol metabolic process Inferred from electronic annotation. Source: InterPro reductive pentose-phosphate cycle Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	fructose 1,6-bisphosphate 1-phosphatase activity Inferred from electronic annotation. Source: EC metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW sedoheptulose-bisphosphatase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 347	347	D-fructose 1,6-bisphosphatase class 2/sedoheptulose 1,7-bisphosphatase		PRO_0000342724
Regions
	Region	100 – 102	3	Substrate binding By similarity
	Region	176 – 178	3	Substrate binding By similarity
	Region	198 – 200	3	Substrate binding By similarity
Sites
	Metal binding	33	1	Manganese 1 By similarity
	Metal binding	57	1	Manganese 1 By similarity
	Metal binding	97	1	Manganese 2 By similarity
	Metal binding	100	1	Manganese 2 By similarity
	Metal binding	225	1	Manganese 2 By similarity
	Binding site	131	1	Substrate By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q8DJE9 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: 5C2FF832B0AC27B3	FASTA	347	37,492
	10 20 30 40 50 60 MDNVIGLEII EVVEQAAIAS ARWMGKGDKN MADQAAVDAM RNRMNQIHMR GRIVIGEGER 70 80 90 100 110 120 DEAPMLYIGE EVGICTRPDA AQYCNPEELI EIDIAVDPCE GTNLCAYGQP GSMAVLAISE 130 140 150 160 170 180 KGGLFAAPDF YMKKLAAPPA AKGKVDIRNS ATENLKILSE CLDRAIDELV VVVMKRDRHN 190 200 210 220 230 240 DLIQEIRDAG ARVQLISDGD VSAALACAFS GTNIHALMGI GAAPEGVISA AAMRALGGHF 250 260 270 280 290 300 QGQLVYDPAV VMTKEWANRT REGNLEELKK AGITDPDKVY EAEELASGET VLFAACGITP 310 320 330 340 GMLMKGVRFF KGGARTQSLV ISTQSKTARF VDTIHMFDQQ LKSLQLY

References

[1]

"Complete genome structure of the thermophilic cyanobacterium Thermosynechococcus elongatus BP-1." Nakamura Y., Kaneko T., Sato S., Ikeuchi M., Katoh H., Sasamoto S., Watanabe A., Iriguchi M., Kawashima K., Kimura T., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A., Nakazaki N., Shimpo S., Sugimoto M. , Takeuchi C., Yamada M., Tabata S. DNA Res. 9:123-130(2002) [PubMed: 12240834] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: BP-1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000039 Genomic DNA. Translation: BAC08828.1.
RefSeq	NP_682066.1. NC_004113.1.
3D structure databases
HSSP	HSSP built from PDB template 1NI9 based on UniProtKB P0A9C9.
ProteinModelPortal	Q8DJE9.
ModBase	Search...
Protein-protein interaction databases
STRING	Q8DJE9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1011253.
GenomeReviews	Gene locus tll1276 in contig BA000039_GR.
KEGG	tel:tll1276.
NMPDR	fig|197221.1.peg.1275.
PATRIC	23927890. VBITheElo119873_1343.
Phylogenomic databases
eggNOG	COG1494.
HOGENOM	HBG284837.
OMA	TSEWADM.
ProtClustDB	PRK09479.
Enzyme and pathway databases
BioCyc	TELO197221:TLL1276-MONOMER.
Family and domain databases
InterPro	IPR004464. FBPase_class-2/SBPase. [Graphical view]
KO	K11532.
Pfam	PF03320. FBPase_glpX. 1 hit. [Graphical view]
PIRSF	PIRSF004532. GlpX. 1 hit.
TIGRFAMs	TIGR00330. GlpX. 1 hit.
ProtoNet	Search...

Entry information

Entry name

FBSB_THEEB

Accession

Primary (citable) accession number: Q8DJE9

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 1, 2008
Last sequence update:	March 1, 2003
Last modified:	January 25, 2012
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program