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Q8DJB1 (K6PF_THEEB) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 67. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
6-phosphofructokinase

Short name=Phosphofructokinase
EC=2.7.1.11
Alternative name(s):
Phosphohexokinase
Gene names
Name:pfkA
Ordered Locus Names:tll1316
OrganismThermosynechococcus elongatus (strain BP-1) [Reference proteome] [HAMAP]
Taxonomic identifier197221 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesThermosynechococcus

Protein attributes

Sequence length369 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + D-fructose 6-phosphate = ADP + D-fructose 1,6-bisphosphate. HAMAP-Rule MF_00339

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 3/4. HAMAP-Rule MF_00339

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00339.

Sequence similarities

Belongs to the phosphofructokinase family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 3693696-phosphofructokinase HAMAP-Rule MF_00339
PRO_0000111997

Regions

Nucleotide binding25 – 295ATP By similarity
Nucleotide binding161 – 1655ATP By similarity
Nucleotide binding178 – 19417ATP By similarity

Sites

Active site1341Proton acceptor By similarity
Metal binding1921Magnesium; via carbonyl oxygen By similarity
Binding site1691Substrate By similarity
Binding site2661Substrate By similarity
Binding site2721Substrate By similarity
Binding site2751Substrate By similarity

Sequences

Sequence LengthMass (Da)Tools
Q8DJB1 [UniParc].

Last modified March 1, 2003. Version 1.
Checksum: 2FE4A8C249105916

FASTA36939,271
        10         20         30         40         50         60 
MSSSRKRLGV FTSGGDCPGL NTAIRAIVAH ATLSYGWEVL GILHATQGLI ERKAIPLNAE 

        70         80         90        100        110        120 
GLGGMDVLLN MGGTILGAIN KGDTLGHADE VIAGYYELGL DALIAICGDG SLRILHQLAQ 

       130        140        150        160        170        180 
KGNWNFLAIP KTIDNDVALT DRAIGFDTAV NTVVEALNRI TSTAASHDRV FVVEVMGRTA 

       190        200        210        220        230        240 
GHLALYSGIA GGADIILIPE IPYSIEGICQ HLQKLRDRWG RQFALIVVAE GSKQLEEDAN 

       250        260        270        280        290        300 
HPRHCSIGQY IADKIAQHSP IPIELRVSVL GHIQRGGAPM AMDRLLAAGM GNTAVDLAAQ 

       310        320        330        340        350        360 
GTFGRMVAWQ AGQVVTVPIA DVVAKCPRHV DPNSFLIRTA QGLGIYVGDK PMLPYVDPTL 


CRDQVICAI 

« Hide

References

[1]"Complete genome structure of the thermophilic cyanobacterium Thermosynechococcus elongatus BP-1."
Nakamura Y., Kaneko T., Sato S., Ikeuchi M., Katoh H., Sasamoto S., Watanabe A., Iriguchi M., Kawashima K., Kimura T., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A., Nakazaki N., Shimpo S., Sugimoto M. expand/collapse author list , Takeuchi C., Yamada M., Tabata S.
DNA Res. 9:123-130(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: BP-1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000039 Genomic DNA. Translation: BAC08868.1.
RefSeqNP_682106.1. NC_004113.1.

3D structure databases

ProteinModelPortalQ8DJB1.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING197221.tll1316.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAC08868; BAC08868; BAC08868.
GeneID1012416.
KEGGtel:tll1316.
PATRIC23927976. VBITheElo119873_1384.

Phylogenomic databases

eggNOGCOG0205.
HOGENOMHOG000248869.
KOK00850.
OMAWVGLMED.
OrthoDBEOG644ZRM.
ProtClustDBPRK03202.

Enzyme and pathway databases

UniPathwayUPA00109; UER00182.

Family and domain databases

HAMAPMF_00339. Phosphofructokinase.
InterProIPR012003. ATP_PFK_prok.
IPR022953. Phosphofructokinase.
IPR015912. Phosphofructokinase_CS.
IPR000023. Phosphofructokinase_dom.
[Graphical view]
PfamPF00365. PFK. 1 hit.
[Graphical view]
PIRSFPIRSF000532. ATP_PFK_prok. 1 hit.
PRINTSPR00476. PHFRCTKINASE.
SUPFAMSSF53784. SSF53784. 1 hit.
PROSITEPS00433. PHOSPHOFRUCTOKINASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameK6PF_THEEB
AccessionPrimary (citable) accession number: Q8DJB1
Entry history
Integrated into UniProtKB/Swiss-Prot: June 16, 2003
Last sequence update: March 1, 2003
Last modified: April 16, 2014
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways