ID   Q8DIX1_THEVB            Unreviewed;       860 AA.
AC   Q8DIX1;
DT   01-MAR-2003, integrated into UniProtKB/TrEMBL.
DT   01-MAR-2003, sequence version 1.
DT   27-MAR-2024, entry version 132.
DE   SubName: Full=Serine/threonine protein kinase {ECO:0000313|EMBL:BAC09012.1};
GN   OrderedLocusNames=tlr1460 {ECO:0000313|EMBL:BAC09012.1};
OS   Thermosynechococcus vestitus (strain NIES-2133 / IAM M-273 / BP-1).
OC   Bacteria; Cyanobacteriota; Cyanophyceae; Acaryochloridales;
OC   Thermosynechococcaceae; Thermosynechococcus.
OX   NCBI_TaxID=197221 {ECO:0000313|EMBL:BAC09012.1, ECO:0000313|Proteomes:UP000000440};
RN   [1] {ECO:0000313|EMBL:BAC09012.1, ECO:0000313|Proteomes:UP000000440}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IAM M-273 / NIES-2133 / BP-1
RC   {ECO:0000313|Proteomes:UP000000440};
RX   PubMed=12240834; DOI=10.1093/dnares/9.4.123;
RA   Nakamura Y., Kaneko T., Sato S., Ikeuchi M., Katoh H., Sasamoto S.,
RA   Watanabe A., Iriguchi M., Kawashima K., Kimura T., Kishida Y., Kiyokawa C.,
RA   Kohara M., Matsumoto M., Matsuno A., Nakazaki N., Shimpo S., Sugimoto M.,
RA   Takeuchi C., Yamada M., Tabata S.;
RT   "Complete genome structure of the thermophilic cyanobacterium
RT   Thermosynechococcus elongatus BP-1.";
RL   DNA Res. 9:123-130(2002).
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DR   EMBL; BA000039; BAC09012.1; -; Genomic_DNA.
DR   RefSeq; NP_682250.1; NC_004113.1.
DR   RefSeq; WP_011057300.1; NC_004113.1.
DR   AlphaFoldDB; Q8DIX1; -.
DR   STRING; 197221.gene:10748060; -.
DR   EnsemblBacteria; BAC09012; BAC09012; BAC09012.
DR   KEGG; tel:tlr1460; -.
DR   PATRIC; fig|197221.4.peg.1532; -.
DR   eggNOG; COG0515; Bacteria.
DR   eggNOG; COG1672; Bacteria.
DR   Proteomes; UP000000440; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   CDD; cd14014; STKc_PknB_like; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR   Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR000719; Prot_kinase_dom.
DR   InterPro; IPR017441; Protein_kinase_ATP_BS.
DR   InterPro; IPR000157; TIR_dom.
DR   InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR   PANTHER; PTHR24363; SERINE/THREONINE PROTEIN KINASE; 1.
DR   PANTHER; PTHR24363:SF0; SERINE_THREONINE-PROTEIN KINASE DDB_G0277989-RELATED; 1.
DR   Pfam; PF14516; AAA_35; 1.
DR   Pfam; PF00069; Pkinase; 1.
DR   Pfam; PF13676; TIR_2; 1.
DR   SMART; SM00220; S_TKc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR   SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR   PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR   PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR   PROSITE; PS50104; TIR; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|PROSITE-ProRule:PRU10141};
KW   Kinase {ECO:0000313|EMBL:BAC09012.1};
KW   Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU10141};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000440};
KW   Serine/threonine-protein kinase {ECO:0000313|EMBL:BAC09012.1};
KW   Transferase {ECO:0000313|EMBL:BAC09012.1}.
FT   DOMAIN          10..282
FT                   /note="Protein kinase"
FT                   /evidence="ECO:0000259|PROSITE:PS50011"
FT   DOMAIN          338..468
FT                   /note="TIR"
FT                   /evidence="ECO:0000259|PROSITE:PS50104"
FT   REGION          303..334
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        303..317
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        318..334
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         41
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ   SEQUENCE   860 AA;  97130 MW;  BBA06FD4486590D2 CRC64;
     MIGKTLGGRY KLIRVLGAGN FGQTFLAEDV HRPIRAKCVV KYLRPARRDA AFLPLARSLF
     QREAQILERL GTHDQIPRLL AYFEEDNEFY LVQDFIEGQV LRQELLLGSG WPEARVIELL
     HDALGILSFV HQCGVIHRDI KPDNLIRRQF DQRLVLIDFG AVKEMGVSIG GGTLVGDANP
     QTIAIGTPGY MAPEQAQGRP RPASDLYSLG MVAVQALTGL SPLQLSQNPY GCWCWQATEP
     VSDRLVQFVN KLIHPSPYER FATAADALAG LQQVEVPKSF WFRLGKFLRT PLQDLWRSPK
     TGEVLPPPLP PVSTLSPQAS EPKPVSSPPA ATTALPNQGR RIFISHSSHG TDLQLASALQ
     EALQKAGHQP FMASQSIRLG EAWAQRIDQE LKQCDFFVLL LSQTAAQSEM VLEEVRTVKQ
     LQAQRGDRRP LILPVRVNFP LDMPLNYELR GYLHRLQQRF WRSPADTDTL LQEILDLVNA
     TTAPVATRSD APQETIAEPD QRNTFVADGP PVPVAEPELP EGQVEVASAF YIERPPIEQR
     CRETLLQPGS LIRIKAPRQM GKTSLMARLL YRATQEGYGT VPLSFQLADA QVFSDLEKLL
     RWLCASVGRR LGLENRLNEY WDDIFGSKYN CTAYFEEYLL PNCQKLGTQF ESRPLVLGLD
     EVDRVFEYPA VASDFFGLLR AWHEEGKNRD IWRNLRLIVV HGTEVYIPLD INQSPFNVGL
     AIDLPEFTQE QIAELCRLHG LSLSEGQLQD LQHLVGGHPY LIRLSLYHLA RQDLTWQELM
     ANAASETGLY RDHLRRQWWH LQQQEDLVPA FRKILQADNG SVVDSTIGFK LHSLGLITLE
     GNLAKVRCDL YRRYFGDRLH
//