Reviewed,
UniProtKB/Swiss-Prot Q8DI68 (ACSF2_SYNEL)
Last modified
November 25, 2008.
Version 40.
History...
Clusters with 100%,
90%,
50% identity |
Documents (2) |
Third-party data |
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Names and origin
| Protein names | Recommended name: Magnesium-protoporphyrin IX monomethyl ester [oxidative] cyclase 2 Short name=Mg-protoporphyrin IX monomethyl ester oxidative cyclase 2 EC=1.14.13.81 | ||||
| Gene names |
| ||||
| Organism | Synechococcus elongatus (Thermosynechococcus elongatus) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 32046 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Cyanobacteria › Chroococcales › Synechococcus |
Protein attributes
| Sequence length | 354 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Function | Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) By similarity. |
| Catalytic activity | Magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + O(2) = 13(1)-hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADP(+) + H(2)O. 13(1)-hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + O(2) = 13(1)-oxo-magnesium-protoporphyrin IX 13-monomethyl ester + NADP(+) + 2 H(2)O. 13(1)-oxo-magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + O(2) = divinylprotochlorophyllide + NADP(+) + 2 H(2)O. |
| Cofactor | Iron By similarity. |
| Pathway | Porphyrin biosynthesis; chlorophyll biosynthesis (light-independent). |
| Sequence similarities | Belongs to the acsF family. |
Ontologies
Keywords | |
|---|---|
| Biological process | Chlorophyll biosynthesis Photosynthesis |
| Ligand | Iron Metal-binding NADP |
| Molecular function | Oxidoreductase |
| Technical term | Complete proteome |
Gene Ontology (GO) | |
| Biological process | chlorophyll biosynthetic process Inferred from electronic annotation. Source: InterPro oxidation reductionInferred from electronic annotation. Source: UniProtKB-KW photosynthesisInferred from electronic annotation. Source: HAMAP |
| Molecular function | iron ion binding Inferred from electronic annotation. Source: HAMAP magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase activityInferred from electronic annotation. Source: HAMAP |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||
Molecule processing | |||||||
|---|---|---|---|---|---|---|---|
| Chain | 1 – 354 | 354 | Magnesium-protoporphyrin IX monomethyl ester [oxidative] cyclase 2 | PRO_0000217536 | |||
Sequences
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References
| [1] | "Complete genome structure of the thermophilic cyanobacterium Thermosynechococcus elongatus BP-1." Nakamura Y., Kaneko T., Sato S., Ikeuchi M., Katoh H., Sasamoto S., Watanabe A., Iriguchi M., Kawashima K., Kimura T., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A., Nakazaki N., Shimpo S., Sugimoto M. Tabata S.DNA Res. 9:123-130(2002) [PubMed: 12240834] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: BP-1. |
Cross-references
Sequence databases | |
|---|---|
| BA000039 Genomic DNA. Translation: BAC09274.1. | |
| RefSeq | NP_682512.1. |
3D structure databases | |
| ModBase | Search... |
Genome annotation databases | |
| GeneID | 1010584. |
| GenomeReviews | Gene locus tlr1722 in contig BA000039_GR. |
| KEGG | tel:tlr1722. |
| NMPDR | fig|197221.1.peg.1721. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| HOGENOM | Q8DI68. |
Enzyme and pathway databases | |
| BioCyc | TELO197221:TLR1722-MON. |
Family and domain databases | |
| HAMAP | MF_01840. [Tree] |
| InterPro | IPR008434. AcsF. IPR003251. Rubrerythrin. [Graphical view] |
| Pfam | PF02915. Rubrerythrin. 1 hit. [Graphical view] |
| TIGRFAMs | TIGR02029. AcsF. 1 hit. |
| ProtoNet | Search... |
Entry information
| Entry name | ACSF2_SYNEL | ||||||||
| Accession | Primary (citable) accession number: Q8DI68 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

Clusters with


