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Protein

UvrABC system protein C

Gene

uvrC

Organism
Thermosynechococcus elongatus (strain BP-1)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionExcision nuclease
Biological processDNA damage, DNA excision, DNA repair, SOS response

Names & Taxonomyi

Protein namesi
Recommended name:
UvrABC system protein CUniRule annotation
Short name:
Protein UvrCUniRule annotation
Alternative name(s):
Excinuclease ABC subunit CUniRule annotation
Gene namesi
Name:uvrCUniRule annotation
Ordered Locus Names:tlr1753
OrganismiThermosynechococcus elongatus (strain BP-1)
Taxonomic identifieri197221 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaSynechococcalesSynechococcaceaeThermosynechococcus
Proteomesi
  • UP000000440 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001383521 – 626UvrABC system protein CAdd BLAST626

Proteomic databases

PRIDEiQ8DI39.

Interactioni

Subunit structurei

Interacts with UvrB in an incision complex.UniRule annotation

Protein-protein interaction databases

STRINGi197221.tlr1753.

Structurei

3D structure databases

ProteinModelPortaliQ8DI39.
SMRiQ8DI39.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini21 – 100GIY-YIGUniRule annotationAdd BLAST80
Domaini218 – 253UVRUniRule annotationAdd BLAST36

Sequence similaritiesi

Belongs to the UvrC family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CII. Bacteria.
COG0322. LUCA.
HOGENOMiHOG000279962.
KOiK03703.
OMAiLFPIRQC.
OrthoDBiPOG091H01BS.

Family and domain databases

Gene3Di3.40.1440.10. 1 hit.
4.10.860.10. 1 hit.
HAMAPiMF_00203. UvrC. 1 hit.
InterProiView protein in InterPro
IPR000305. GIY-YIG_endonuc.
IPR035901. GIY-YIG_endonuc_sf.
IPR010994. RuvA_2-like.
IPR001943. UVR_dom.
IPR036876. UVR_dom_sf.
IPR004791. UvrC.
IPR001162. UvrC_homol_region.
PfamiView protein in Pfam
PF01541. GIY-YIG. 1 hit.
PF02151. UVR. 1 hit.
PF08459. UvrC_HhH_N. 1 hit.
SMARTiView protein in SMART
SM00465. GIYc. 1 hit.
SUPFAMiSSF46600. SSF46600. 1 hit.
SSF47781. SSF47781. 1 hit.
SSF82771. SSF82771. 1 hit.
TIGRFAMsiTIGR00194. uvrC. 1 hit.
PROSITEiView protein in PROSITE
PS50164. GIY_YIG. 1 hit.
PS50151. UVR. 1 hit.
PS50165. UVRC. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8DI39-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLQPLIQDRD RLEQVLRQLP LAPGVYFLKD KTDQILYIGK SKRLRSRVRS
60 70 80 90 100
YFREPAQLGP RLERMVYQVA EIEFIVTDTE AEALALEANL IKQHQPHFNV
110 120 130 140 150
LLKDDKKYPY VCITWSEPYP RIFITRKRQF GNGGDPRSDS AKDRYYGPYV
160 170 180 190 200
DSFRLRQTLA LVKRLFPLRQ RPRPLFRDRP CLNYDIGRCP GVCQGLISPQ
210 220 230 240 250
EYRQTLQRVA MIFQGRTGEL VAQLQAQMAQ AAADLNFELA ARLRDQIRGL
260 270 280 290 300
EHLGVDQKVS LPDDTVSRDA IALAVGDRHA AIQLFQIRAG RLVGRLAFVA
310 320 330 340 350
DAQSGSAGTI LQRVLEEHYA QVEDVEIPSE ILLQHPLPEP DFLRTYLSEK
360 370 380 390 400
KGRAVTLTVP QRQAKAELIA MVQRNAELEL ARLQQASDRT QTALEDLAQL
410 420 430 440 450
LGLDTLPHRI EGYDISHIQG SDAVASRVVF IDGLPAQQHY RHYNIRNPEV
460 470 480 490 500
KLGHSDDFAS LAEILRRRFA PYLEGQGETP DDWPDIILID GGKGQLSAVV
510 520 530 540 550
QVLEPLLEEL TLVSLAKQRE DIFLPHQRQP LPADPEQPGV QLLRRVRDEA
560 570 580 590 600
HRFALNFHRQ KRAQRQRRSH LDQIPGLGYQ RQKELLATFR SIDYIRMATP
610 620
EQLAQVNGVG PRLAARIYRY FHPDAD
Length:626
Mass (Da):71,615
Last modified:March 1, 2003 - v1
Checksum:i4888D63D86B1AE6D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000039 Genomic DNA. Translation: BAC09305.1.
RefSeqiNP_682543.1. NC_004113.1.
WP_011057590.1. NC_004113.1.

Genome annotation databases

EnsemblBacteriaiBAC09305; BAC09305; BAC09305.
GeneIDi1011020.
KEGGitel:tlr1753.
PATRICifig|197221.4.peg.1834.

Similar proteinsi

Entry informationi

Entry nameiUVRC_THEEB
AccessioniPrimary (citable) accession number: Q8DI39
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 16, 2003
Last sequence update: March 1, 2003
Last modified: October 25, 2017
This is version 88 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families