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Q8DI29 (ISPT_THEEB) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 67. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Isoprenyl transferase
EC=2.5.1.-
Gene names
Name:uppS
Ordered Locus Names:tlr1763
OrganismThermosynechococcus elongatus (strain BP-1) [Reference proteome] [HAMAP]
Taxonomic identifier197221 [NCBI]
Taxonomic lineageBacteria › Cyanobacteria › Oscillatoriophycideae › Chroococcales › Thermosynechococcus ›

Protein attributes

Sequence length251 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids By similarity. HAMAP-Rule MF_01139

Cofactor

Binds 2 magnesium ions per subunit By similarity.

Subunit structure

Homodimer By similarity.

Sequence similarities

Belongs to the UPP synthase family.

Ontologies

Keywords
   LigandMagnesium
Metal-binding
   Molecular functionTransferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Molecular_functionmagnesium ion binding

Inferred from electronic annotation. Source: HAMAP

prenyltransferase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 251251Isoprenyl transferase HAMAP-Rule MF_01139
PRO_0000123698

Regions

Region32 – 354Substrate binding By similarity
Region76 – 783Substrate binding By similarity
Region205 – 2073Substrate binding By similarity

Sites

Active site311 By similarity
Active site791Proton acceptor By similarity
Metal binding311Magnesium By similarity
Metal binding2181Magnesium By similarity
Binding site361Substrate By similarity
Binding site441Substrate By similarity
Binding site481Substrate By similarity
Binding site801Substrate By similarity
Binding site821Substrate By similarity
Binding site1991Substrate By similarity

Sequences

Sequence LengthMass (Da)Tools
Q8DI29 [UniParc].

Last modified March 1, 2003. Version 1.
Checksum: 06CB750363BB80E3

FASTA25128,760
        10         20         30         40         50         60 
MSMTLQPHSL IELPADLDRD RLPRHVAVIM DGNGRWAKQR NLPRIMGHQR GVDTLKDLLR 

        70         80         90        100        110        120 
CCKDWGIEAL TAYAFSTENW GRPLPEVEFL MTLFEQVLRR ELGEMVAEGV QIHFVGDLTC 

       130        140        150        160        170        180 
LPKSLQAEIE RAVAATANNQ KIKFVVATNY GGRREIIHAC RSIAAQVKAG LLDPADIDEV 

       190        200        210        220        230        240 
LFERHLYTGG LPDPDLLIRT SGELRISNFF LWQVAYAEIY VTKTLWPDFD RSAFHEALRD 

       250 
YQQRQRRFGR V

« Hide

References

[1]"Complete genome structure of the thermophilic cyanobacterium Thermosynechococcus elongatus BP-1."
Nakamura Y., Kaneko T., Sato S., Ikeuchi M., Katoh H., Sasamoto S., Watanabe A., Iriguchi M., Kawashima K., Kimura T., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A., Nakazaki N., Shimpo S., Sugimoto M. expand/collapse author list , Takeuchi C., Yamada M., Tabata S.
DNA Res. 9:123-130(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: BP-1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BA000039 Genomic DNA. Translation: BAC09315.1.
RefSeqNP_682553.1. NC_004113.1.

3D structure databases

ProteinModelPortalQ8DI29.
ModBaseSearch...

Protein-protein interaction databases

STRING197221.tlr1763.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAC09315; BAC09315; BAC09315.
GeneID1010999.
KEGGtel:tlr1763.
PATRIC23928908. VBITheElo119873_1844.

Phylogenomic databases

eggNOGCOG0020.
HOGENOMHOG000006056.
KOK00806.
OMAIAYSELF.
ProtClustDBPRK14831.

Family and domain databases

Gene3D3.40.1180.10. 1 hit.
HAMAPMF_01139. ISPT.
InterProIPR001441. UPP_synth-like.
IPR018520. UPP_synth-like_CS.
[Graphical view]
PANTHERPTHR10291. PTHR10291. 1 hit.
PfamPF01255. Prenyltransf. 1 hit.
[Graphical view]
SUPFAMSSF64005. UPP_synth. 1 hit.
TIGRFAMsTIGR00055. uppS. 1 hit.
PROSITEPS01066. UPP_SYNTHASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameISPT_THEEB
AccessionPrimary (citable) accession number: Q8DI29
Entry history
Integrated into UniProtKB/Swiss-Prot: February 16, 2004
Last sequence update: March 1, 2003
Last modified: May 1, 2013
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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