Q8DI01 (FABZ_THEEB) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase
Short name=(3R)-hydroxymyristoyl ACP dehydrase
EC=4.2.1.-

Gene names

Name:	fabZ
Ordered Locus Names:	tlr1791

Organism

Thermosynechococcus elongatus (strain BP-1)

Taxonomic identifier

197221 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Chroococcales › Thermosynechococcus

Protein attributes

Sequence length	153 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Involved in saturated fatty acids biosynthesis. HAMAP MF_00406
Subcellular location	Cytoplasm By similarity HAMAP MF_00406.
Sequence similarities	Belongs to the thioester dehydratase family. FabZ subfamily.

Ontologies

Keywords
Biological process	Lipid A biosynthesis Lipid synthesis
Cellular component	Cytoplasm
Molecular function	Lyase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	fatty acid biosynthetic process Inferred from electronic annotation. Source: InterPro lipid A biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	hydro-lyase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 153	153	(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase HAMAP MF_00406		PRO_0000091750
Sites
	Active site	59	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q8DI01 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: 60CF5D78F9BB8BC2	FASTA	153	17,140
	10 20 30 40 50 60 MPTLTDSPPT TVLTVTELQQ LLPHRYPFLL VDRIIDYVPE KYAVGLKNVT INEPFFQGHF 70 80 90 100 110 120 PGRPIMPGVL IVEALAQVGG VVLMQMNWAK DKLSVFAGID KVRFRRPVVP GDQLILRAEL 130 140 150 LVVKQQRIGK MQGRAEVNGQ LVCEGEMMFS LVD

References

[1]

"Complete genome structure of the thermophilic cyanobacterium Thermosynechococcus elongatus BP-1." Nakamura Y., Kaneko T., Sato S., Ikeuchi M., Katoh H., Sasamoto S., Watanabe A., Iriguchi M., Kawashima K., Kimura T., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A., Nakazaki N., Shimpo S., Sugimoto M. , Takeuchi C., Yamada M., Tabata S. DNA Res. 9:123-130(2002) [PubMed: 12240834] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: BP-1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000039 Genomic DNA. Translation: BAC09343.1.
RefSeq	NP_682581.1. NC_004113.1.
3D structure databases
ProteinModelPortal	Q8DI01.
ModBase	Search...
Protein-protein interaction databases
STRING	Q8DI01.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1012465.
GenomeReviews	Gene locus tlr1791 in contig BA000039_GR.
KEGG	tel:tlr1791.
NMPDR	fig|197221.1.peg.1790.
PATRIC	23928966. VBITheElo119873_1873.
Phylogenomic databases
eggNOG	COG0764.
HOGENOM	HBG433282.
OMA	KERRGVA.
ProtClustDB	PRK00006.
Enzyme and pathway databases
BioCyc	TELO197221:TLR1791-MONOMER.
Family and domain databases
HAMAP	MF_00406. FabZ. [Tree]
InterPro	IPR013114. FabA_FabZ. IPR010084. FabZ. [Graphical view]
KO	K02372.
Pfam	PF07977. FabA. 1 hit. [Graphical view]
TIGRFAMs	TIGR01750. FabZ. 1 hit.
ProtoNet	Search...

Entry information

Entry name

FABZ_THEEB

Accession

Primary (citable) accession number: Q8DI01

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 4, 2003
Last sequence update:	March 1, 2003
Last modified:	January 25, 2012
This is version 52 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program