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Q8DHY6

- SPEA_THEEB

UniProt

Q8DHY6 - SPEA_THEEB

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Protein
Biosynthetic arginine decarboxylase
Gene
speA, tll1807
Organism
Thermosynechococcus elongatus (strain BP-1)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the biosynthesis of agmatine from arginine By similarity.UniRule annotation

Catalytic activityi

L-arginine = agmatine + CO2.UniRule annotation

Cofactori

Magnesium By similarity.UniRule annotation
Pyridoxal phosphate By similarity.UniRule annotation

GO - Molecular functioni

  1. arginine decarboxylase activity Source: UniProtKB-HAMAP
  2. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. arginine catabolic process Source: InterPro
  2. spermidine biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Decarboxylase, Lyase

Keywords - Biological processi

Polyamine biosynthesis, Spermidine biosynthesis

Keywords - Ligandi

Magnesium, Metal-binding, Pyridoxal phosphate

Names & Taxonomyi

Protein namesi
Recommended name:
Biosynthetic arginine decarboxylase (EC:4.1.1.19)
Short name:
ADC
Gene namesi
Name:speA
Ordered Locus Names:tll1807
OrganismiThermosynechococcus elongatus (strain BP-1)
Taxonomic identifieri197221 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesThermosynechococcus
ProteomesiUP000000440: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 637637Biosynthetic arginine decarboxylaseUniRule annotation
PRO_0000149979Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei107 – 1071N6-(pyridoxal phosphate)lysine By similarity

Interactioni

Protein-protein interaction databases

STRINGi197221.tll1807.

Structurei

3D structure databases

ProteinModelPortaliQ8DHY6.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni289 – 29911Substrate-binding Reviewed prediction
Add
BLAST

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG1166.
HOGENOMiHOG000029191.
KOiK01585.
OMAiIDHYVDG.
OrthoDBiEOG676Z0R.

Family and domain databases

Gene3Di2.40.37.10. 2 hits.
3.20.20.10. 1 hit.
HAMAPiMF_01417. SpeA.
InterProiIPR009006. Ala_racemase/Decarboxylase_C.
IPR002985. Arg_decrbxlase.
IPR022643. De-COase2_C.
IPR022657. De-COase2_CS.
IPR022644. De-COase2_N.
IPR022653. De-COase2_pyr-phos_BS.
IPR000183. Orn/DAP/Arg_de-COase.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF02784. Orn_Arg_deC_N. 1 hit.
PF00278. Orn_DAP_Arg_deC. 1 hit.
[Graphical view]
PIRSFiPIRSF001336. Arg_decrbxlase. 1 hit.
PRINTSiPR01180. ARGDCRBXLASE.
PR01179. ODADCRBXLASE.
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsiTIGR01273. speA. 1 hit.
PROSITEiPS00878. ODR_DC_2_1. 1 hit.
PS00879. ODR_DC_2_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8DHY6-1 [UniParc]FASTAAdd to Basket

« Hide

MALTVTKTSN WTIEDSEQLY RIQGWGEPYF GINAAGHVTV SPKGDRGGSL    50
DLYELVQALQ QRNISLPLLL RFSDILEDRI ERLNACFARA IARYGYQGAY 100
KGVFPIKCNQ QRHIIEALVR FGQSHQFGLE AGSKPELLIA LAMLNTPGAL 150
LICNGYKDRS YIETAILARR LGHTSIIVLE QPEEVAEVIA VSQALGIEPI 200
VGVRAKLSTQ GVGRWGTSAG DRAKFGLTVP EILTAVEQLR AAGMLNALQL 250
LHFHIGSQIS AISVIKDAIR EAGQIYGELV RLGANMQYLD VGGGLGVDYD 300
GSKTNFHASK NYSMQNYASD VVAGIKDACR QRGIPDPTLI SESGRAIASH 350
QSVLIFNVLG VSEVPKITPE PATAEEHLII RNLYDTYQAI DENNYQEAYN 400
DALQFKGEAI SLFNFGYLSL PERARAESLF WACCAKILGI ARQQEYVPDD 450
LEDLEKIMAS IYYINLSVFQ SVPDSWAIDQ LFPIMPIHRL DEEPTERGIL 500
ADLTCDSDGK IDQFIDLRDV KSVLELHPFR PGEPYYLGLF LNGAYQEIMG 550
NLHNLFGDTN AVHIRLTPKG YEIEHLVRGD TMQEVLGYVQ YQGDALLEKI 600
RCRTEAALAE EQITLAEAQH LLENYERSLR SYTYLSS 637
Length:637
Mass (Da):70,856
Last modified:March 1, 2003 - v1
Checksum:iA924C72CB50F29C5
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000039 Genomic DNA. Translation: BAC09359.1.
RefSeqiNP_682597.1. NC_004113.1.

Genome annotation databases

EnsemblBacteriaiBAC09359; BAC09359; BAC09359.
GeneIDi1012401.
KEGGitel:tll1807.
PATRICi23928998. VBITheElo119873_1889.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000039 Genomic DNA. Translation: BAC09359.1 .
RefSeqi NP_682597.1. NC_004113.1.

3D structure databases

ProteinModelPortali Q8DHY6.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 197221.tll1807.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAC09359 ; BAC09359 ; BAC09359 .
GeneIDi 1012401.
KEGGi tel:tll1807.
PATRICi 23928998. VBITheElo119873_1889.

Phylogenomic databases

eggNOGi COG1166.
HOGENOMi HOG000029191.
KOi K01585.
OMAi IDHYVDG.
OrthoDBi EOG676Z0R.

Family and domain databases

Gene3Di 2.40.37.10. 2 hits.
3.20.20.10. 1 hit.
HAMAPi MF_01417. SpeA.
InterProi IPR009006. Ala_racemase/Decarboxylase_C.
IPR002985. Arg_decrbxlase.
IPR022643. De-COase2_C.
IPR022657. De-COase2_CS.
IPR022644. De-COase2_N.
IPR022653. De-COase2_pyr-phos_BS.
IPR000183. Orn/DAP/Arg_de-COase.
IPR029066. PLP-binding_barrel.
[Graphical view ]
Pfami PF02784. Orn_Arg_deC_N. 1 hit.
PF00278. Orn_DAP_Arg_deC. 1 hit.
[Graphical view ]
PIRSFi PIRSF001336. Arg_decrbxlase. 1 hit.
PRINTSi PR01180. ARGDCRBXLASE.
PR01179. ODADCRBXLASE.
SUPFAMi SSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsi TIGR01273. speA. 1 hit.
PROSITEi PS00878. ODR_DC_2_1. 1 hit.
PS00879. ODR_DC_2_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: BP-1.

Entry informationi

Entry nameiSPEA_THEEB
AccessioniPrimary (citable) accession number: Q8DHY6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 29, 2004
Last sequence update: March 1, 2003
Last modified: June 11, 2014
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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