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Q8DHH6

- TRMB_THEEB

UniProt

Q8DHH6 - TRMB_THEEB

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Protein

tRNA (guanine-N(7)-)-methyltransferase

Gene
trmB, tll1983
Organism
Thermosynechococcus elongatus (strain BP-1)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA By similarity.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + guanine(46) in tRNA = S-adenosyl-L-homocysteine + N(7)-methylguanine(46) in tRNA.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei44 – 441S-adenosyl-L-methionine By similarity
Binding sitei69 – 691S-adenosyl-L-methionine By similarity
Binding sitei96 – 961S-adenosyl-L-methionine By similarity
Active sitei119 – 1191 By similarity
Binding sitei119 – 1191S-adenosyl-L-methionine By similarity
Binding sitei123 – 1231Substrate By similarity
Binding sitei155 – 1551Substrate By similarity

GO - Molecular functioni

  1. tRNA (guanine-N7-)-methyltransferase activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Methyltransferase, Transferase

Keywords - Biological processi

tRNA processing

Keywords - Ligandi

S-adenosyl-L-methionine

Enzyme and pathway databases

UniPathwayiUPA00989.

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA (guanine-N(7)-)-methyltransferase (EC:2.1.1.33)
Alternative name(s):
tRNA (guanine(46)-N(7))-methyltransferase
tRNA(m7G46)-methyltransferase
Gene namesi
Name:trmB
Ordered Locus Names:tll1983
OrganismiThermosynechococcus elongatus (strain BP-1)
Taxonomic identifieri197221 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesThermosynechococcus
ProteomesiUP000000440: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 213213tRNA (guanine-N(7)-)-methyltransferaseUniRule annotationPRO_0000171409Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi197221.tll1983.

Structurei

3D structure databases

ProteinModelPortaliQ8DHH6.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0220.
HOGENOMiHOG000237936.
KOiK03439.
OMAiRVTIQFP.
OrthoDBiEOG6K6VBC.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
HAMAPiMF_01057. tRNA_methyltr_TrmB.
InterProiIPR029063. SAM-dependent_MTases-like.
IPR003358. tRNA_(Gua-N-7)_MeTrfase.
[Graphical view]
PfamiPF02390. Methyltransf_4. 1 hit.
[Graphical view]
SUPFAMiSSF53335. SSF53335. 1 hit.
TIGRFAMsiTIGR00091. TIGR00091. 1 hit.
PROSITEiPS51625. SAM_MT_TRMB. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8DHH6-1 [UniParc]FASTAAdd to Basket

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MSDRAMVVRV RQHVNPLSQK FQQDIPVPDW SRIYEQPSQP LHLDIGCARG    50
TFLLEMAALY PEQNFLGLEI RYPLVVAANE RRDRQQLRNL HYLWGNANVH 100
LSKILGGLPL HTVTIQFPDP WFKRRHHKRR VVTPELVATL AELLPAGGRV 150
VLQSDVFEVA ESMVQQFRAH GAFRSTCTDW LPQSPWPVAT EREKCVLNKG 200
LAVYRWQFER CAV 213
Length:213
Mass (Da):24,627
Last modified:March 1, 2003 - v1
Checksum:i99A8B50045A37D1C
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000039 Genomic DNA. Translation: BAC09535.1.
RefSeqiNP_682773.1. NC_004113.1.

Genome annotation databases

EnsemblBacteriaiBAC09535; BAC09535; BAC09535.
GeneIDi1010362.
KEGGitel:tll1983.
PATRICi23929372. VBITheElo119873_2073.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000039 Genomic DNA. Translation: BAC09535.1 .
RefSeqi NP_682773.1. NC_004113.1.

3D structure databases

ProteinModelPortali Q8DHH6.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 197221.tll1983.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAC09535 ; BAC09535 ; BAC09535 .
GeneIDi 1010362.
KEGGi tel:tll1983.
PATRICi 23929372. VBITheElo119873_2073.

Phylogenomic databases

eggNOGi COG0220.
HOGENOMi HOG000237936.
KOi K03439.
OMAi RVTIQFP.
OrthoDBi EOG6K6VBC.

Enzyme and pathway databases

UniPathwayi UPA00989 .

Family and domain databases

Gene3Di 3.40.50.150. 1 hit.
HAMAPi MF_01057. tRNA_methyltr_TrmB.
InterProi IPR029063. SAM-dependent_MTases-like.
IPR003358. tRNA_(Gua-N-7)_MeTrfase.
[Graphical view ]
Pfami PF02390. Methyltransf_4. 1 hit.
[Graphical view ]
SUPFAMi SSF53335. SSF53335. 1 hit.
TIGRFAMsi TIGR00091. TIGR00091. 1 hit.
PROSITEi PS51625. SAM_MT_TRMB. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: BP-1.

Entry informationi

Entry nameiTRMB_THEEB
AccessioniPrimary (citable) accession number: Q8DHH6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 16, 2003
Last sequence update: March 1, 2003
Last modified: June 11, 2014
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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