ID   Q8DHG0_THEVB            Unreviewed;       790 AA.
AC   Q8DHG0;
DT   01-MAR-2003, integrated into UniProtKB/TrEMBL.
DT   01-MAR-2003, sequence version 1.
DT   27-MAR-2024, entry version 104.
DE   SubName: Full=Tlr1999 protein {ECO:0000313|EMBL:BAC09551.1};
GN   OrderedLocusNames=tlr1999 {ECO:0000313|EMBL:BAC09551.1};
OS   Thermosynechococcus vestitus (strain NIES-2133 / IAM M-273 / BP-1).
OC   Bacteria; Cyanobacteriota; Cyanophyceae; Acaryochloridales;
OC   Thermosynechococcaceae; Thermosynechococcus.
OX   NCBI_TaxID=197221 {ECO:0000313|EMBL:BAC09551.1, ECO:0000313|Proteomes:UP000000440};
RN   [1] {ECO:0000313|EMBL:BAC09551.1, ECO:0000313|Proteomes:UP000000440}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IAM M-273 / NIES-2133 / BP-1
RC   {ECO:0000313|Proteomes:UP000000440};
RX   PubMed=12240834; DOI=10.1093/dnares/9.4.123;
RA   Nakamura Y., Kaneko T., Sato S., Ikeuchi M., Katoh H., Sasamoto S.,
RA   Watanabe A., Iriguchi M., Kawashima K., Kimura T., Kishida Y., Kiyokawa C.,
RA   Kohara M., Matsumoto M., Matsuno A., Nakazaki N., Shimpo S., Sugimoto M.,
RA   Takeuchi C., Yamada M., Tabata S.;
RT   "Complete genome structure of the thermophilic cyanobacterium
RT   Thermosynechococcus elongatus BP-1.";
RL   DNA Res. 9:123-130(2002).
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DR   EMBL; BA000039; BAC09551.1; -; Genomic_DNA.
DR   RefSeq; NP_682789.1; NC_004113.1.
DR   AlphaFoldDB; Q8DHG0; -.
DR   STRING; 197221.gene:10748607; -.
DR   EnsemblBacteria; BAC09551; BAC09551; BAC09551.
DR   KEGG; tel:tlr1999; -.
DR   eggNOG; COG2197; Bacteria.
DR   eggNOG; COG2203; Bacteria.
DR   eggNOG; COG5001; Bacteria.
DR   Proteomes; UP000000440; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   CDD; cd01948; EAL; 1.
DR   CDD; cd01949; GGDEF; 1.
DR   Gene3D; 3.30.450.40; -; 1.
DR   Gene3D; 3.30.70.270; -; 1.
DR   Gene3D; 3.40.50.2300; -; 1.
DR   Gene3D; 3.20.20.450; EAL domain; 1.
DR   InterPro; IPR011006; CheY-like_superfamily.
DR   InterPro; IPR001633; EAL_dom.
DR   InterPro; IPR035919; EAL_sf.
DR   InterPro; IPR003018; GAF.
DR   InterPro; IPR029016; GAF-like_dom_sf.
DR   InterPro; IPR000160; GGDEF_dom.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR016132; Phyto_chromo_attachment.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   NCBIfam; TIGR00254; GGDEF; 1.
DR   PANTHER; PTHR33121; CYCLIC DI-GMP PHOSPHODIESTERASE PDEF; 1.
DR   PANTHER; PTHR33121:SF85; CYCLIC DI-GMP PHOSPHODIESTERASE PDEK-RELATED; 1.
DR   Pfam; PF00563; EAL; 1.
DR   Pfam; PF01590; GAF; 1.
DR   Pfam; PF00990; GGDEF; 1.
DR   SMART; SM00052; EAL; 1.
DR   SMART; SM00065; GAF; 1.
DR   SMART; SM00267; GGDEF; 1.
DR   SUPFAM; SSF52172; CheY-like; 1.
DR   SUPFAM; SSF141868; EAL domain-like; 1.
DR   SUPFAM; SSF55781; GAF domain-like; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   PROSITE; PS50883; EAL; 1.
DR   PROSITE; PS50887; GGDEF; 1.
DR   PROSITE; PS50046; PHYTOCHROME_2; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Kinase {ECO:0000256|ARBA:ARBA00022777};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000440};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          191..327
FT                   /note="Phytochrome chromophore attachment site"
FT                   /evidence="ECO:0000259|PROSITE:PS50046"
FT   DOMAIN          390..523
FT                   /note="GGDEF"
FT                   /evidence="ECO:0000259|PROSITE:PS50887"
FT   DOMAIN          532..789
FT                   /note="EAL"
FT                   /evidence="ECO:0000259|PROSITE:PS50883"
SQ   SEQUENCE   790 AA;  90218 MW;  C6919CCF5C21B14A CRC64;
     MIEKLLVLSA VDDCPSESLS PLEVVTEESV PKYPQKKCLS PLTNLLVIEN IPQSGEILYP
     HLAEIDYIRY QVHTCLYSHL TPGVVAQAKP NLLVLIAQGD DVLKAVQTLQ QRYPHLPLIV
     IDPSDRPDLA TQVLHSGAQD YLTIEELTPN LLARSIRHAI DRHQVEQQLL RQAQYDRLLV
     QITQHIHQSL ELSTILETTV KDVRELLGCD RVLIYRFLDD WRGIMDVEAV VPPWLSALGD
     VVGDSCFTEQ YVEAYKRGRI HVVNSLEKAS VAPCYRDLLA HYQVKANLVV PIVVEGRLWG
     LLICHQCAHP RNWQDSEIEL IKQISTQLAI AILQAELYQK AQREIQERKE VEAQLLYQAR
     HDHLTHLPNR WLFEDQVRLS LNHAAAHSDF HYAVLCLDLD RFKTLNDSLG HAIGDLLLQA
     FAKRLTRCVS PQDVVARLGS DEFAVLLNDI QGIEQAQAIA QRLRERLNHP FEIDHYTLYT
     TVSIGLVMGD AHYKSTEELL RDADMAMYYA KSKGHNRIDI FDPMMLQQVR DRLHLEVELR
     QAIDQGDFAL YYQPIINLRS QSPRGFEALV RWQKEDTLIS PTVFIPVAEE TGLIFELSRW
     VLRSACEQLQ QWQKRYPKLR SLGFTVSINL SANQFSLPTL VAEIEQALEH HHLAGQFLKI
     EITESTLMHH LDSACEILTK LKAMGVRINI DDFGTGYSSL SYLRNLPLDG IKIDRSFISQ
     MDRSQEDLEL VRTILVLARN LHLDCIAEGI ESTTQLQLLR SLRCPFGQGY LFAPPLTADK
     AEVYLQKHIL
//