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Q8DGS1

- Q8DGS1_THEEB

UniProt

Q8DGS1 - Q8DGS1_THEEB

Protein
Submitted name:

Protein serin-threonin phosphatase

Gene

tlr2243

Organism
Thermosynechococcus elongatus (strain BP-1)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 75 (01 Oct 2014)
      Sequence version 1 (01 Mar 2003)
      Previous versions | rss
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    Functioni

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi34 – 341CalciumImported
    Metal bindingi34 – 341Magnesium 1Imported
    Metal bindingi193 – 1931CalciumImported
    Metal bindingi193 – 1931Magnesium 1Imported
    Metal bindingi198 – 1981Magnesium 2Imported
    Metal bindingi227 – 2271Magnesium 2; via tele nitrogenImported
    Metal bindingi231 – 2311CalciumImported
    Metal bindingi231 – 2311Magnesium 1Imported

    GO - Molecular functioni

    1. catalytic activity Source: InterPro
    2. metal ion binding Source: UniProtKB-KW
    3. protein binding Source: IntAct

    Keywords - Ligandi

    CalciumImported, MagnesiumImported, Metal-bindingImported

    Protein family/group databases

    PptaseDBiP3D1010191.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Protein serin-threonin phosphataseImported
    Gene namesi
    Ordered Locus Names:tlr2243Imported
    OrganismiThermosynechococcus elongatus (strain BP-1)Imported
    Taxonomic identifieri197221 [NCBI]
    Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesThermosynechococcus
    ProteomesiUP000000440: Chromosome

    Interactioni

    Binary interactionsi

    WithEntry#Exp.IntActNotes
    glnBP0A3F48EBI-7629960,EBI-700889From a different organism.

    Protein-protein interaction databases

    IntActiQ8DGS1. 1 interaction.
    MINTiMINT-8299485.
    STRINGi197221.tlr2243.

    Structurei

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    2J82X-ray1.28A1-240[»]
    2J86X-ray3.05A/B1-240[»]
    2XZVX-ray1.60A1-240[»]
    2Y09X-ray1.70A1-240[»]
    ProteinModelPortaliQ8DGS1.
    SMRiQ8DGS1. Positions 1-240.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiQ8DGS1.

    Family & Domainsi

    Phylogenomic databases

    eggNOGiCOG0631.
    HOGENOMiHOG000235782.
    KOiK01090.
    OMAiHEECQGM.
    OrthoDBiEOG65N17S.

    Family and domain databases

    Gene3Di3.60.40.10. 1 hit.
    InterProiIPR001932. PP2C-like_dom.
    IPR015655. Protein_Pase_2C.
    [Graphical view]
    PANTHERiPTHR13832. PTHR13832. 1 hit.
    SMARTiSM00331. PP2C_SIG. 1 hit.
    SM00332. PP2Cc. 1 hit.
    [Graphical view]
    SUPFAMiSSF81606. SSF81606. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q8DGS1-1 [UniParc]FASTAAdd to Basket

    « Hide

    MDVAGLTDCG LIRKSNQDAF YIDEKHQRFF IVADGMGGHA GGEEASRLAV    50
    DHIRQYLETH LEDLQHDPVT LLRQAFLAAN HAIVEQQRQN SARADMGTTA 100
    VVILLDEKGD RAWCAHVGDS RIYRWRKDQL QQITSDHTWI AQAVQLGSLT 150
    IEQARQHPWR HVLSQCLGRE DLSQIDIQPI DLEPGDRLLL CSDGLTEELT 200
    DDVISIYLSE PNVQKAAAAL VDAAKTHGGR DNVTVVVISV 240
    Length:240
    Mass (Da):26,704
    Last modified:March 1, 2003 - v1
    Checksum:iA06C145E28654D9F
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000039 Genomic DNA. Translation: BAC09795.1.
    RefSeqiNP_683033.1. NC_004113.1.
    WP_011058076.1. NC_004113.1.

    Genome annotation databases

    EnsemblBacteriaiBAC09795; BAC09795; BAC09795.
    GeneIDi1010671.
    KEGGitel:tlr2243.
    PATRICi23929932. VBITheElo119873_2352.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000039 Genomic DNA. Translation: BAC09795.1 .
    RefSeqi NP_683033.1. NC_004113.1.
    WP_011058076.1. NC_004113.1.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    2J82 X-ray 1.28 A 1-240 [» ]
    2J86 X-ray 3.05 A/B 1-240 [» ]
    2XZV X-ray 1.60 A 1-240 [» ]
    2Y09 X-ray 1.70 A 1-240 [» ]
    ProteinModelPortali Q8DGS1.
    SMRi Q8DGS1. Positions 1-240.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    IntActi Q8DGS1. 1 interaction.
    MINTi MINT-8299485.
    STRINGi 197221.tlr2243.

    Protein family/group databases

    PptaseDBi P3D1010191.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAC09795 ; BAC09795 ; BAC09795 .
    GeneIDi 1010671.
    KEGGi tel:tlr2243.
    PATRICi 23929932. VBITheElo119873_2352.

    Phylogenomic databases

    eggNOGi COG0631.
    HOGENOMi HOG000235782.
    KOi K01090.
    OMAi HEECQGM.
    OrthoDBi EOG65N17S.

    Miscellaneous databases

    EvolutionaryTracei Q8DGS1.

    Family and domain databases

    Gene3Di 3.60.40.10. 1 hit.
    InterProi IPR001932. PP2C-like_dom.
    IPR015655. Protein_Pase_2C.
    [Graphical view ]
    PANTHERi PTHR13832. PTHR13832. 1 hit.
    SMARTi SM00331. PP2C_SIG. 1 hit.
    SM00332. PP2Cc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF81606. SSF81606. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: BP-1Imported.
    2. "Structural analysis of the PP2C phosphatase tPphA from Thermosynechococcus elongatus: a flexible flap subdomain controls access to the catalytic site."
      Schlicker C., Fokina O., Kloft N., Grune T., Becker S., Sheldrick G.M., Forchhammer K.
      J. Mol. Biol. 376:570-581(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (1.28 ANGSTROMS) IN COMPLEX WITH CALCIUM AND MAGNESIUM.
    3. "A third metal is required for catalytic activity of the signal-transducing protein phosphatase M tPphA."
      Su J., Schlicker C., Forchhammer K.
      J. Biol. Chem. 286:13481-13488(2011) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (1.60 ANGSTROMS) IN COMPLEX WITH CALCIUM AND MAGNESIUM.

    Entry informationi

    Entry nameiQ8DGS1_THEEB
    AccessioniPrimary (citable) accession number: Q8DGS1
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 1, 2003
    Last sequence update: March 1, 2003
    Last modified: October 1, 2014
    This is version 75 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    3D-structureImported, Complete proteome, Reference proteomeImported

    External Data

    Dasty 3