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Protein
Submitted name:

Protein serin-threonin phosphatase

Gene

tlr2243

Organism
Thermosynechococcus elongatus (strain BP-1)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi34 – 341CalciumCombined sources
Metal bindingi34 – 341Magnesium 1Combined sources
Metal bindingi193 – 1931CalciumCombined sources
Metal bindingi193 – 1931Magnesium 1Combined sources
Metal bindingi198 – 1981Magnesium 2Combined sources
Metal bindingi227 – 2271Magnesium 2; via tele nitrogenCombined sources
Metal bindingi231 – 2311CalciumCombined sources
Metal bindingi231 – 2311Magnesium 1Combined sources

GO - Molecular functioni

Complete GO annotation...

Keywords - Ligandi

CalciumCombined sources, MagnesiumCombined sources, Metal-bindingCombined sources

Names & Taxonomyi

Protein namesi
Submitted name:
Protein serin-threonin phosphataseImported
Gene namesi
Ordered Locus Names:tlr2243Imported
OrganismiThermosynechococcus elongatus (strain BP-1)Imported
Taxonomic identifieri197221 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesThermosynechococcus
ProteomesiUP000000440 Componenti: Chromosome

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
glnBP0A3F48EBI-7629960,EBI-700889From a different organism.

Protein-protein interaction databases

IntActiQ8DGS1. 1 interaction.
MINTiMINT-8299485.
STRINGi197221.tlr2243.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2J82X-ray1.28A1-240[»]
2J86X-ray3.05A/B1-240[»]
2XZVX-ray1.60A1-240[»]
2Y09X-ray1.70A1-240[»]
ProteinModelPortaliQ8DGS1.
SMRiQ8DGS1. Positions 1-240.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ8DGS1.

Family & Domainsi

Phylogenomic databases

eggNOGiCOG0631.
HOGENOMiHOG000235782.
KOiK01090.
OMAiFFIVADG.
OrthoDBiEOG65N17S.

Family and domain databases

Gene3Di3.60.40.10. 1 hit.
InterProiIPR015655. PP2C.
IPR001932. PPM-type_phosphatase_dom.
[Graphical view]
PANTHERiPTHR13832. PTHR13832. 1 hit.
SMARTiSM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMiSSF81606. SSF81606. 1 hit.
PROSITEiPS51746. PPM_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8DGS1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDVAGLTDCG LIRKSNQDAF YIDEKHQRFF IVADGMGGHA GGEEASRLAV
60 70 80 90 100
DHIRQYLETH LEDLQHDPVT LLRQAFLAAN HAIVEQQRQN SARADMGTTA
110 120 130 140 150
VVILLDEKGD RAWCAHVGDS RIYRWRKDQL QQITSDHTWI AQAVQLGSLT
160 170 180 190 200
IEQARQHPWR HVLSQCLGRE DLSQIDIQPI DLEPGDRLLL CSDGLTEELT
210 220 230 240
DDVISIYLSE PNVQKAAAAL VDAAKTHGGR DNVTVVVISV
Length:240
Mass (Da):26,704
Last modified:March 1, 2003 - v1
Checksum:iA06C145E28654D9F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000039 Genomic DNA. Translation: BAC09795.1.
RefSeqiNP_683033.1. NC_004113.1.
WP_011058076.1. NC_004113.1.

Genome annotation databases

EnsemblBacteriaiBAC09795; BAC09795; BAC09795.
GeneIDi1010671.
KEGGitel:tlr2243.
PATRICi23929932. VBITheElo119873_2352.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000039 Genomic DNA. Translation: BAC09795.1.
RefSeqiNP_683033.1. NC_004113.1.
WP_011058076.1. NC_004113.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2J82X-ray1.28A1-240[»]
2J86X-ray3.05A/B1-240[»]
2XZVX-ray1.60A1-240[»]
2Y09X-ray1.70A1-240[»]
ProteinModelPortaliQ8DGS1.
SMRiQ8DGS1. Positions 1-240.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ8DGS1. 1 interaction.
MINTiMINT-8299485.
STRINGi197221.tlr2243.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAC09795; BAC09795; BAC09795.
GeneIDi1010671.
KEGGitel:tlr2243.
PATRICi23929932. VBITheElo119873_2352.

Phylogenomic databases

eggNOGiCOG0631.
HOGENOMiHOG000235782.
KOiK01090.
OMAiFFIVADG.
OrthoDBiEOG65N17S.

Miscellaneous databases

EvolutionaryTraceiQ8DGS1.

Family and domain databases

Gene3Di3.60.40.10. 1 hit.
InterProiIPR015655. PP2C.
IPR001932. PPM-type_phosphatase_dom.
[Graphical view]
PANTHERiPTHR13832. PTHR13832. 1 hit.
SMARTiSM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMiSSF81606. SSF81606. 1 hit.
PROSITEiPS51746. PPM_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: BP-1Imported.
  2. "Structural analysis of the PP2C phosphatase tPphA from Thermosynechococcus elongatus: a flexible flap subdomain controls access to the catalytic site."
    Schlicker C., Fokina O., Kloft N., Grune T., Becker S., Sheldrick G.M., Forchhammer K.
    J. Mol. Biol. 376:570-581(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (1.28 ANGSTROMS) IN COMPLEX WITH CALCIUM AND MAGNESIUM.
  3. "A third metal is required for catalytic activity of the signal-transducing protein phosphatase M tPphA."
    Su J., Schlicker C., Forchhammer K.
    J. Biol. Chem. 286:13481-13488(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (1.60 ANGSTROMS) IN COMPLEX WITH CALCIUM AND MAGNESIUM.

Entry informationi

Entry nameiQ8DGS1_THEEB
AccessioniPrimary (citable) accession number: Q8DGS1
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: June 24, 2015
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.