Q8DGP3 (TRPF_THEEB) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
N-(5'-phosphoribosyl)anthranilate isomerase
Short name=PRAI
EC=5.3.1.24

Gene names

Name:	trpF
Ordered Locus Names:	tll2272

Organism

Thermosynechococcus elongatus (strain BP-1) [Reference proteome] [HAMAP]

Taxonomic identifier

197221 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Cyanobacteria › Oscillatoriophycideae › Chroococcales › Thermosynechococcus › Thermosynechococcus elongatus

Protein attributes

Sequence length	230 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate. HAMAP-Rule MF_00135
Pathway	Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 3/5. HAMAP-Rule MF_00135
Sequence similarities	Belongs to the TrpF family.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis Tryptophan biosynthesis
Molecular function	Isomerase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	tryptophan biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular_function	phosphoribosylanthranilate isomerase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 230	230	N-(5'-phosphoribosyl)anthranilate isomerase HAMAP-Rule MF_00135		PRO_0000154388

Sequences

	Sequence		Length	Mass (Da)
	Q8DGP3 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: D529F450D5E7141F	FASTA	230	24,368
	10 20 30 40 50 60 MLNSTIPARI AVKICGLTLP EQAIAIAQMG VSALGFITVP HSPRYVSAPT IAEICRQLPP 70 80 90 100 110 120 AVLTVAVVAN LDLEALANLV TTTGVQALQL HGSESPEFCQ SVRQTFPNIV LIKALRVQSA 130 140 150 160 170 180 ATLAAIPAYA STVDRILLDA YHPQQLGGTG QPFDWTLLKA LHIPCPWWLA GGITPENCRQ 190 200 210 220 230 AIAQTQPQGI DLASGVESRP GVKDLGRVAA LLSNLGINAN HSLYPEGSRF

References

[1]

"Complete genome structure of the thermophilic cyanobacterium Thermosynechococcus elongatus BP-1." Nakamura Y., Kaneko T., Sato S., Ikeuchi M., Katoh H., Sasamoto S., Watanabe A., Iriguchi M., Kawashima K., Kimura T., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A., Nakazaki N., Shimpo S., Sugimoto M. , Takeuchi C., Yamada M., Tabata S. DNA Res. 9:123-130(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: BP-1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000039 Genomic DNA. Translation: BAC09824.1.
RefSeq	NP_683062.1. NC_004113.1.
3D structure databases
ProteinModelPortal	Q8DGP3.
ModBase	Search...
Protein-protein interaction databases
STRING	197221.tll2272.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	BAC09824; BAC09824; BAC09824.
GeneID	1012229.
KEGG	tel:tll2272.
PATRIC	23930000. VBITheElo119873_2381.
Phylogenomic databases
eggNOG	COG0135.
HOGENOM	HOG000161598.
KO	K01817.
OMA	FVNASRC.
ProtClustDB	PRK01222.
Enzyme and pathway databases
UniPathway	UPA00035; UER00042.
Family and domain databases
Gene3D	3.20.20.70. 1 hit.
HAMAP	MF_00135. PRAI.
InterPro	IPR013785. Aldolase_TIM. IPR001240. PRAI. IPR011060. RibuloseP-bd_barrel. [Graphical view]
Pfam	PF00697. PRAI. 1 hit. [Graphical view]
SUPFAM	SSF51366. RibP_bind_barrel. 1 hit.
ProtoNet	Search...

Entry information

Entry name

TRPF_THEEB

Accession

Primary (citable) accession number: Q8DGP3

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 25, 2003
Last sequence update:	March 1, 2003
Last modified:	May 1, 2013
This is version 61 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program