ID   Q8DGN6_THEVB            Unreviewed;       654 AA.
AC   Q8DGN6;
DT   01-MAR-2003, integrated into UniProtKB/TrEMBL.
DT   01-MAR-2003, sequence version 1.
DT   27-MAR-2024, entry version 92.
DE   SubName: Full=Adenylate cyclase {ECO:0000313|EMBL:BAC09832.1};
GN   OrderedLocusNames=tll2280 {ECO:0000313|EMBL:BAC09832.1};
OS   Thermosynechococcus vestitus (strain NIES-2133 / IAM M-273 / BP-1).
OC   Bacteria; Cyanobacteriota; Cyanophyceae; Acaryochloridales;
OC   Thermosynechococcaceae; Thermosynechococcus.
OX   NCBI_TaxID=197221 {ECO:0000313|EMBL:BAC09832.1, ECO:0000313|Proteomes:UP000000440};
RN   [1] {ECO:0000313|EMBL:BAC09832.1, ECO:0000313|Proteomes:UP000000440}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IAM M-273 / NIES-2133 / BP-1
RC   {ECO:0000313|Proteomes:UP000000440};
RX   PubMed=12240834; DOI=10.1093/dnares/9.4.123;
RA   Nakamura Y., Kaneko T., Sato S., Ikeuchi M., Katoh H., Sasamoto S.,
RA   Watanabe A., Iriguchi M., Kawashima K., Kimura T., Kishida Y., Kiyokawa C.,
RA   Kohara M., Matsumoto M., Matsuno A., Nakazaki N., Shimpo S., Sugimoto M.,
RA   Takeuchi C., Yamada M., Tabata S.;
RT   "Complete genome structure of the thermophilic cyanobacterium
RT   Thermosynechococcus elongatus BP-1.";
RL   DNA Res. 9:123-130(2002).
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DR   EMBL; BA000039; BAC09832.1; -; Genomic_DNA.
DR   RefSeq; NP_683070.1; NC_004113.1.
DR   AlphaFoldDB; Q8DGN6; -.
DR   STRING; 197221.gene:10748897; -.
DR   EnsemblBacteria; BAC09832; BAC09832; BAC09832.
DR   KEGG; tel:tll2280; -.
DR   PATRIC; fig|197221.4.peg.2390; -.
DR   eggNOG; COG2114; Bacteria.
DR   eggNOG; COG4252; Bacteria.
DR   Proteomes; UP000000440; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProt.
DR   GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   CDD; cd07302; CHD; 1.
DR   Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR   InterPro; IPR001054; A/G_cyclase.
DR   InterPro; IPR007890; CHASE2.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   PANTHER; PTHR43081; ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC-RELATED; 1.
DR   PANTHER; PTHR43081:SF1; PH-SENSITIVE ADENYLATE CYCLASE RV1264; 1.
DR   Pfam; PF05226; CHASE2; 1.
DR   Pfam; PF00211; Guanylate_cyc; 1.
DR   SMART; SM01080; CHASE2; 1.
DR   SMART; SM00044; CYCc; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000440};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        322..344
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        351..372
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        378..399
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          446..584
FT                   /note="Guanylate cyclase"
FT                   /evidence="ECO:0000259|PROSITE:PS50125"
SQ   SEQUENCE   654 AA;  72458 MW;  9519257B64DE4E90 CRC64;
     MLPLLSHFRR TFADLGLIVV VSTLASTVVI GIRQMGWLQP LELGAYDRLM QWRPMPGPDP
     RLLVVAVTEA DIQRYRSLSL PDQVYAQALQ KLLKHQPRAI GLDIYRDFPM PPGHEELNRL
     WLSSDRLFAV TKLGNATHPT IRPPAALSAD QVGFNDVTVD AGGIIRRSLL FLPDDQGNTL
     YSFSLRLALR YLADEGIEPR GSDADPYVMQ LGQSIFTPLQ PNDGGYVGAD TAGYQVMLNY
     RGDERAVTWV PLEDVLTERV APELIRDRVV LIGNIAESGK DFFYTPFSSG LRDNQRMAGV
     FIHAQMVGQF IDAGLGDRAV IWFWPDSVET VWIVLWALLG GILAWRVRHP LALGTAVAAA
     LLLLLLVCYG LFLKLGWVPL VPPALTLLLS SGGVVTYTAQ QAQQQRQMVM RLLGQSISPE
     IAAALWERRD QLLKDGKLPG QRLIATLLFT DLKGFSTISE RMEPEELFNW LNAYLEKVAD
     VVQSYHGVIN KFTGDGIMAV FGVPIKRTSR EGIAIDARNA VDCALALGQL LEELNREWAA
     QGLPQVMMRA GIYTGPIVVG SLGSKNRLEY GVIGDSVNTA SRLESVDKHR QPSPCRILVA
     QETLAYLGDR YEVEAWGPLE LKGKERKIQV FRILGIRQGL AIAPNQPTAI ELEI
//