Skip Header

Contribute Send feedback
Read comments (?) or add your own

Q8DGM2 (DAPF_THEEB) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 50. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Diaminopimelate epimerase
Short name=DAP epimerase
EC=5.1.1.7
Gene names
Name:dapF
Ordered Locus Names:tll2294
OrganismThermosynechococcus elongatus (strain BP-1)
Taxonomic identifier197221 [NCBI]
Taxonomic lineageBacteria › Cyanobacteria › Chroococcales › Thermosynechococcus

Protein attributes

Sequence length286 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

LL-2,6-diaminoheptanedioate = meso-diaminoheptanedioate. HAMAP MF_00197

Pathway

Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; DL-2,6-diaminopimelate from LL-2,6-diaminopimelate: step 1/1. HAMAP MF_00197

Subcellular location

Cytoplasm By similarity HAMAP MF_00197.

Sequence similarities

Belongs to the diaminopimelate epimerase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Lysine biosynthesis
   Cellular componentCytoplasm
   Molecular functionIsomerase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological processlysine biosynthetic process via diaminopimelate

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functiondiaminopimelate epimerase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 286286Diaminopimelate epimerase HAMAP MF_00197
PRO_0000149872

Sites

Active site751 By similarity
Active site2251 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q8DGM2 [UniParc].

Last modified March 1, 2003. Version 1.
Checksum: 0B2B75CA4AB05666

FASTA28630,994
        10         20         30         40         50         60 
MSLSFQKYQG LGNDFLLIDN RHQEELLLTP EQAQFWCDRH FGVGADGVIF LLRGTGESDY 

        70         80         90        100        110        120 
RMRMYNADGS VAQMCGNGIR CLAKFIFALE GRSAGEIVRY RIDTLAGLIV PEVQADGQVT 

       130        140        150        160        170        180 
VDMGKPRLLA QQIPTTLAAA DQKVVDVPLT VGDRQWLVTC VSMGNPHCVT FVEDVAALDL 

       190        200        210        220        230        240 
AVLGPQFEHH PAFPQRTNTE FVQVLGSDRL RMRVWERGAG MTLACGTGAC ATLVAAVLTG 

       250        260        270        280 
CLSPGGDQAQ ATVELPGGDL QIRWDLPSQH LYMTGPALAV FSGTLP

« Hide

References

[1]"Complete genome structure of the thermophilic cyanobacterium Thermosynechococcus elongatus BP-1."
Nakamura Y., Kaneko T., Sato S., Ikeuchi M., Katoh H., Sasamoto S., Watanabe A., Iriguchi M., Kawashima K., Kimura T., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A., Nakazaki N., Shimpo S., Sugimoto M. expand/collapse author list , Takeuchi C., Yamada M., Tabata S.
DNA Res. 9:123-130(2002) [PubMed: 12240834] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: BP-1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BA000039 Genomic DNA. Translation: BAC09846.1.
RefSeqNP_683084.1. NC_004113.1.

3D structure databases

ProteinModelPortalQ8DGM2.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ8DGM2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1010752.
GenomeReviewsGene locus tll2294 in contig BA000039_GR.
KEGGtel:tll2294.
NMPDRfig|197221.1.peg.2293.
PATRIC23930046. VBITheElo119873_2403.

Phylogenomic databases

eggNOGCOG0253.
HOGENOMHBG399442.
OMAFMTGPAT.
ProtClustDBPRK00450.

Enzyme and pathway databases

BioCycTELO197221:TLL2294-MONOMER.

Family and domain databases

HAMAPMF_00197. DAP_epimerase.
[Tree]
InterProIPR018510. DAP_epimerase_AS.
IPR001653. DAP_epimerase_DapF.
[Graphical view]
KOK01778.
PfamPF01678. DAP_epimerase. 2 hits.
[Graphical view]
TIGRFAMsTIGR00652. DapF. 1 hit.
PROSITEPS01326. DAP_EPIMERASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameDAPF_THEEB
AccessionPrimary (citable) accession number: Q8DGM2
Entry history
Integrated into UniProtKB/Swiss-Prot: April 11, 2003
Last sequence update: March 1, 2003
Last modified: January 25, 2012
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents