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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Vibrio vulnificus (strain CMCP6)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:VV1_0145
OrganismiVibrio vulnificus (strain CMCP6)
Taxonomic identifieri216895 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio

Subcellular locationi

Q8DFR1:
  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001516341 – 577Arginine--tRNA ligaseAdd BLAST577

Interactioni

Subunit structurei

Monomer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliQ8DFR1.
SMRiQ8DFR1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi122 – 132"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C75. Bacteria.
COG0018. LUCA.
HOGENOMiHOG000247212.
KOiK01887.
OMAiNKPLHLG.
OrthoDBiPOG091H01RF.

Family and domain databases

CDDicd00671. ArgRS_core. 1 hit.
Gene3Di1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPiMF_00123. Arg_tRNA_synth. 1 hit.
InterProiView protein in InterPro
IPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR036695. Arg-tRNA-synth_N_sf.
IPR035684. ArgRS_core.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_Ia_anticodon-bd.
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiView protein in Pfam
PF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
PRINTSiPR01038. TRNASYNTHARG.
SMARTiView protein in SMART
SM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.
PROSITEiView protein in PROSITE
PS00178. AA_TRNA_LIGASE_I. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8DFR1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNIQALINDK VSQALEAAGA PAGSPAAVRQ SAKPQFGDYQ ANGVMGVAKQ
60 70 80 90 100
LGTNPREFAQ KVLDVLDLDG IASKTEIAGP GFINIFLSEE FLAKQAEAAL
110 120 130 140 150
ADPRLGVASE EAQTIVADYS APNVAKEMHV GHLRSTIIGD AVVRTLEFLG
160 170 180 190 200
HKVIRANHIG DWGTQFGMLI ANLERVQQES GEVSMELADL EGFYRESKKL
210 220 230 240 250
YDEDEEFAVK ARGYVVKLQS GDEFCAEMWK KLVDVTMIQN QRNYDRLNVS
260 270 280 290 300
LSRDDVMGES MYNDMLPKIV ADLKAQGLAV EDDGAQVVFL EEFKNKDGEP
310 320 330 340 350
MGVIVQKRDG GFLYTTTDIA CAKYRYEELG ADRVLYFIDS RQHQHLMQAW
360 370 380 390 400
TIVRKAGYVP ESVSLEHHAF GMMLGKDGKP FKTRAGGTVR LADLLDEAEV
410 420 430 440 450
RAAQLIESKN PELAEDEKKA IANTVAMAAV KYADLSKHRT TDYVFDWDNM
460 470 480 490 500
LAFEGNTAPY MQYAYTRVAS VFAKAGVSMD DLQGEIKITD EKEKALIAKL
510 520 530 540 550
MQFEEAVQSV AREGQPHIMC SYLFELAGQF SSFYEACPIL VAEDEAVKQS
560 570
RLKLAALTAK TIKQGLSLLG IDTLERM
Length:577
Mass (Da):63,768
Last modified:March 1, 2003 - v1
Checksum:i7E22A92721C5BD39
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016795 Genomic DNA. Translation: AAO08683.1.
RefSeqiWP_011078262.1. NC_004459.3.

Genome annotation databases

EnsemblBacteriaiAAO08683; AAO08683; VV1_0145.
KEGGivvu:VV1_0145.

Similar proteinsi

Entry informationi

Entry nameiSYR_VIBVU
AccessioniPrimary (citable) accession number: Q8DFR1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 23, 2003
Last sequence update: March 1, 2003
Last modified: October 25, 2017
This is version 94 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families